Cas no 327183-32-4 (Chroman-8-carbaldehyde)

Chroman-8-carbaldehyde is a versatile organic compound featuring a chroman (benzodihydropyran) core with a formyl group at the 8-position. This structure makes it a valuable intermediate in synthetic organic chemistry, particularly for the preparation of heterocyclic compounds, pharmaceuticals, and fine chemicals. The aldehyde functionality offers reactivity for further derivatization, including condensation, reduction, or nucleophilic addition reactions. Its chroman scaffold is of interest in medicinal chemistry due to its presence in bioactive molecules. The compound is typically characterized by high purity and stability under standard conditions, ensuring reliable performance in research and industrial applications. Proper handling and storage are recommended to maintain its integrity.
Chroman-8-carbaldehyde structure
Chroman-8-carbaldehyde structure
Product Name:Chroman-8-carbaldehyde
CAS No:327183-32-4
MF:C10H10O2
MW:162.185203075409
MDL:MFCD12198125
CID:1004135
PubChem ID:22265336
Update Time:2025-11-02

Chroman-8-carbaldehyde Chemical and Physical Properties

Names and Identifiers

    • Chroman-8-carbaldehyde
    • 2H-1-Benzopyran-8-carboxaldehyde, 3,4-dihydro-
    • 3,4-dihydro-2H-chromene-8-carbaldehyde
    • 8-chromanal
    • 8-formyl-3,4-dihydro-2H-1-benzopyran
    • chroman-8-carboxaldehyde
    • chromane-8-carbaldehyde
    • 3,4-dihydro-2H-1-benzopyran-8-carbaldehyde
    • CS-0101660
    • ZYKTXRDSAFQAAM-UHFFFAOYSA-N
    • DTXSID90624057
    • MFCD12198125
    • DS-19850
    • A918805
    • CNA18332
    • 327183-32-4
    • AKOS006344813
    • SCHEMBL894456
    • FT-0705546
    • Y11371
    • SY278204
    • DB-068686
    • MDL: MFCD12198125
    • Inchi: 1S/C10H10O2/c11-7-9-4-1-3-8-5-2-6-12-10(8)9/h1,3-4,7H,2,5-6H2
    • InChI Key: ZYKTXRDSAFQAAM-UHFFFAOYSA-N
    • SMILES: O1C2C(C=O)=CC=CC=2CCC1

Computed Properties

  • Exact Mass: 162.06800
  • Monoisotopic Mass: 162.068079557g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 12
  • Rotatable Bond Count: 1
  • Complexity: 167
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 1.7
  • Topological Polar Surface Area: 26.3?2

Experimental Properties

  • PSA: 26.30000
  • LogP: 1.82410

Chroman-8-carbaldehyde Security Information

Chroman-8-carbaldehyde Pricemore >>

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Additional information on Chroman-8-carbaldehyde

Exploring the Versatile Applications and Properties of Chroman-8-carbaldehyde (CAS No. 327183-32-4)

Chroman-8-carbaldehyde (CAS No. 327183-32-4) is a specialized organic compound that has garnered significant attention in the fields of medicinal chemistry, fragrance development, and material science. This compound, characterized by its chromane backbone and an aldehyde functional group at the 8-position, serves as a crucial intermediate in the synthesis of various bioactive molecules. Researchers and industry professionals are increasingly interested in Chroman-8-carbaldehyde derivatives due to their potential applications in drug discovery and functional materials.

The structural uniqueness of Chroman-8-carbaldehyde makes it a valuable building block in organic synthesis. Its chromane core is a common motif in many natural products and pharmaceuticals, while the aldehyde group offers a reactive site for further chemical modifications. This dual functionality has led to its widespread use in the development of novel heterocyclic compounds, which are essential in creating new therapeutic agents and advanced materials.

In recent years, the demand for Chroman-8-carbaldehyde has surged, particularly in the pharmaceutical sector. The compound's ability to serve as a precursor for antioxidant agents and anti-inflammatory drugs aligns with current health trends focused on oxidative stress management and chronic disease prevention. Many researchers are exploring its potential in designing neuroprotective compounds, responding to the growing global concern about neurodegenerative disorders.

The fragrance industry has also shown considerable interest in Chroman-8-carbaldehyde and its derivatives. The compound's structural features contribute to the creation of novel synthetic aroma chemicals that mimic natural fragrances. With consumers increasingly seeking unique and long-lasting scents, Chroman-8-carbaldehyde-based fragrances offer perfumers new creative possibilities while addressing the industry's need for sustainable and stable aroma compounds.

From a synthetic chemistry perspective, Chroman-8-carbaldehyde presents interesting challenges and opportunities. The development of efficient synthetic routes to Chroman-8-carbaldehyde has become a topic of research, with scientists exploring various catalytic systems and green chemistry approaches. Recent advancements in asymmetric synthesis have opened new pathways to obtain enantiomerically pure forms of this compound, which is particularly valuable for pharmaceutical applications.

The material science community has begun investigating Chroman-8-carbaldehyde for its potential in creating advanced functional materials. Its ability to form stable complexes with various metals and its photophysical properties make it an attractive candidate for developing organic electronic materials and sensors. This aligns with current technological trends toward flexible electronics and smart materials.

Quality control and analytical characterization of Chroman-8-carbaldehyde remain crucial aspects for researchers and manufacturers. Advanced techniques such as HPLC analysis of Chroman-8-carbaldehyde and spectroscopic characterization ensure the compound meets the required purity standards for various applications. The development of reliable analytical methods for Chroman-8-carbaldehyde continues to be an active area of research.

As the scientific community's understanding of Chroman-8-carbaldehyde deepens, its potential applications continue to expand. Current research is exploring its use in bioconjugation chemistry and as a scaffold for molecular probes, addressing the growing need for tools in biological research and diagnostics. The compound's versatility ensures it will remain relevant in multiple scientific disciplines for years to come.

The commercial availability of Chroman-8-carbaldehyde has improved significantly in recent years, with several specialty chemical suppliers now offering this compound. However, challenges remain in scaling up production while maintaining quality and purity. The development of cost-effective manufacturing processes for Chroman-8-carbaldehyde is an ongoing focus for the chemical industry.

Looking ahead, Chroman-8-carbaldehyde is poised to play an increasingly important role in various scientific and industrial applications. Its unique structural features and reactivity profile make it a valuable asset in the toolkit of synthetic chemists, material scientists, and pharmaceutical researchers alike. As new applications continue to emerge, this compound will undoubtedly remain at the forefront of innovation in multiple fields.

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