Cas no 327-54-8 (1,2,4,5-tetrafluorobenzene)

1,2,4,5-Tetrafluorobenzene (C?H?F?) is a fluorinated aromatic compound characterized by its high thermal and chemical stability. Its symmetrical structure and electron-withdrawing fluorine substituents make it a valuable intermediate in organic synthesis, particularly for pharmaceuticals, agrochemicals, and liquid crystal materials. The compound exhibits low reactivity toward nucleophilic substitution, enhancing its utility in harsh reaction conditions. Its high purity and consistent performance are critical for applications requiring precise fluorination or as a building block in advanced material science. Additionally, 1,2,4,5-tetrafluorobenzene serves as a precursor for polymers and specialty chemicals, offering excellent solvation properties and compatibility with fluorinated systems.
1,2,4,5-tetrafluorobenzene structure
1,2,4,5-tetrafluorobenzene structure
Product Name:1,2,4,5-tetrafluorobenzene
CAS No:327-54-8
MF:C6H2F4
MW:150.073695659637
MDL:MFCD00000307
CID:36860
PubChem ID:9474
Update Time:2025-10-22

1,2,4,5-tetrafluorobenzene Chemical and Physical Properties

Names and Identifiers

    • 1,2,4,5-tetrafluorobenzene
    • Tetrafluorobenzoic acid 2,3,4,5-
    • 1,2,4,5-C6F4H2
    • 1,2,4,5-tetrafluoro-benzene
    • 1,2,4,5-tetraflurobenzene
    • 1,4,5-Tetrafluorobenzene
    • 2,3,5,6-tetrafluorobenzene
    • 2,5,6-Tetrafluorobenzene
    • Benzene,1,2,4,5-tetrafluoro
    • NSC 10249
    • p-Tetrafluorobenzene
    • Benzene,2,4,5-tetrafluoro-
    • AB3CL8US2H
    • 1,2,4,5-tetrakis(fluoranyl)benzene
    • A821398
    • T1029
    • 2,3,5,6-tetrafluoro benzene
    • AKOS006223912
    • AC-10613
    • NSC-10249
    • 327-54-8
    • s10424
    • DTXSID90186367
    • W-106824
    • 2,3,5,6-Tetrafluorobenzene;p-Tetrafluorobenzene
    • NSC10249
    • MFCD00000307
    • EINECS 206-319-3
    • FT-0631958
    • NS00041536
    • 1,2,4,5-Tetrafluorobenzene, >=99%
    • AM20040175
    • CS-0020157
    • EN300-97145
    • 1, 2, 4, 5-tetrafluorobenzene
    • Benzene, 1,2,4,5-tetrafluoro-
    • GS-3490
    • Z1203162141
    • SCHEMBL530766
    • DB-018726
    • 92511-33-6
    • PHENYL, 2,3,5,6-TETRAFLUORO-
    • DTXCID00108858
    • DTXSID401309196
    • 2,3,5,6-Tetrafluorobenzene;NSC 10249;p-Tetrafluorobenzene;
    • 206-319-3
    • MDL: MFCD00000307
    • Inchi: 1S/C6H2F4/c7-3-1-4(8)6(10)2-5(3)9/h1-2H
    • InChI Key: SDXUIOOHCIQXRP-UHFFFAOYSA-N
    • SMILES: FC1C=C(C(=CC=1F)F)F
    • BRN: 1909052

Computed Properties

  • Exact Mass: 150.00900
  • Monoisotopic Mass: 150.009263
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 0
  • Heavy Atom Count: 10
  • Rotatable Bond Count: 0
  • Complexity: 90.3
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: nothing
  • XLogP3: 2.3
  • Topological Polar Surface Area: 0

Experimental Properties

  • Color/Form: Not available
  • Density: 1.344?g/mL?at 25?°C(lit.)
  • Melting Point: 4?°C (lit.)
  • Boiling Point: 90°C
  • Flash Point: Fahrenheit: 60.8 ° f
    Celsius: 16 ° c
  • Refractive Index: n20/D 1.407(lit.)
  • Water Partition Coefficient: Not miscible or difficult to mix in water.
  • PSA: 0.00000
  • LogP: 2.24300
  • Solubility: Not available

1,2,4,5-tetrafluorobenzene Security Information

1,2,4,5-tetrafluorobenzene Customs Data

  • HS CODE:2903999090
  • Customs Data:

    China Customs Code:

    2903999090

    Overview:

    2903999090 Other aromatic halogenated derivatives. VAT:17.0% Tax refund rate:9.0% Regulatory conditions:nothing MFN tariff:5.5% general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

1,2,4,5-tetrafluorobenzene Pricemore >>

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1,2,4,5-tetrafluorobenzene Suppliers

Suzhou Senfeida Chemical Co., Ltd
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(CAS:327-54-8)1,2,4,5-Tetrafluorobenzene
Order Number:1647612;sfd12419
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Quantity:Company Customization/200kg
Purity:98%/99.9%
Pricing Information Last Updated:Monday, 14 April 2025 21:49
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Amadis Chemical Company Limited
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(CAS:327-54-8)1,2,4,5-tetrafluorobenzene
Order Number:A1204027
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Quantity:500g
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 02:51
Price ($):375.0
Tiancheng Chemical (Jiangsu) Co., Ltd
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(CAS:327-54-8)1,2,4,5-四氟苯
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Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 12:31
Price ($):discuss personally

1,2,4,5-tetrafluorobenzene Related Literature

Additional information on 1,2,4,5-tetrafluorobenzene

1,2,4,5-Tetrafluorobenzene: A Comprehensive Overview

1,2,4,5-Tetrafluorobenzene (CAS No. 327-54-8) is a fluorinated aromatic compound with significant applications in various industries. This compound is characterized by its unique chemical structure, which consists of a benzene ring with four fluorine atoms substituted at the 1, 2, 4, and 5 positions. The presence of fluorine atoms imparts distinct chemical and physical properties to the molecule, making it highly versatile in different fields such as materials science, electronics, and pharmaceuticals.

Recent studies have highlighted the importance of 1,2,4,5-tetrafluorobenzene in the development of advanced materials. Researchers have explored its potential as a precursor for synthesizing fluorinated polymers and high-performance composites. These materials exhibit excellent thermal stability and mechanical strength, making them ideal for use in aerospace and automotive industries. The ability of 1,2,4,5-tetrafluorobenzene to undergo various chemical reactions has further expanded its utility in the synthesis of novel compounds with tailored properties.

The synthesis of 1,2,4,5-tetrafluorobenzene typically involves electrophilic substitution reactions on benzene rings. Recent advancements in catalytic methods have enabled more efficient and selective synthesis pathways. For instance, the use of palladium-catalyzed coupling reactions has been reported to enhance the yield and purity of the compound. These improvements are crucial for meeting the growing demand in industrial applications while maintaining environmental sustainability.

In the field of electronics, 1,2,4,5-tetrafluorobenzene has found applications in the production of high-frequency dielectrics and optoelectronic devices. Its low dielectric constant and high refractive index make it suitable for use in advanced semiconductor materials. Recent research has also focused on incorporating this compound into organic light-emitting diodes (OLEDs), where it contributes to improved device efficiency and stability.

The environmental impact of 1,2,4,5-tetrafluorobenzene has been a topic of interest among scientists. Studies have shown that this compound exhibits low toxicity to aquatic organisms under controlled conditions. However, further research is needed to fully understand its long-term effects on ecosystems. Regulatory bodies are increasingly emphasizing the need for sustainable practices in the handling and disposal of such compounds to minimize environmental risks.

From a pharmaceutical perspective, 1,2,4,5-tetrafluorobenzene has been explored as a building block for drug discovery. Its fluorinated structure offers unique opportunities for designing molecules with enhanced bioavailability and pharmacokinetic profiles. Recent breakthroughs in medicinal chemistry have leveraged this compound to develop potential candidates for treating various diseases, including cancer and infectious disorders.

In conclusion,1,2,4,5-tetrafluorobenzene (CAS No.327-54-8) is a versatile compound with wide-ranging applications across multiple industries. Its unique chemical properties and reactivity continue to drive innovative research and development efforts. As scientific understanding advances,1,2,4,5-tetrafluorobenzene is expected to play an even more significant role in shaping future technologies and therapeutic solutions.

Recommended suppliers
Suzhou Senfeida Chemical Co., Ltd
(CAS:327-54-8)1,2,4,5-Tetrafluorobenzene
1647612;sfd12419
Purity:98%/99.9%
Quantity:Company Customization/200kg
Price ($):Inquiry/Inquiry
Email
Amadis Chemical Company Limited
(CAS:327-54-8)1,2,4,5-tetrafluorobenzene
A1204027
Purity:99%
Quantity:500g
Price ($):375.0
Email