• 1. Emulsifier-free, organotellurium-mediated living radical emulsion polymerization (emulsion TERP) of styrene: poly(dimethylaminoethyl methacrylate) macro-TERP agent?
  Yukiya Kitayama Polym. Chem., 2014,5, 2784-2792
• 2. Enantio- & chemo-selective preparation of enantiomerically enriched aliphatic nitro alcohols using Candida parapsilosis ATCC 7330
  Sowmyalakshmi Venkataraman RSC Adv., 2015,5, 73807-73813
• 3. Evolution of shape, size, and areal density of a single plane of Si nanocrystals embedded in SiO2 matrix studied by atom probe tomography
  Bin Han,Yasuo Shimizu,Gabriele Seguini,Celia Castro,Gérard Ben Assayag,Koji Inoue,Yasuyoshi Nagai,Sylvie Schamm-Chardon,Michele Perego RSC Adv., 2016,6, 3617-3622
• 4. Fast synthesis of copper nanoclusters through the use of hydrogen peroxide additive and their application for the fluorescence detection of Hg2+ in water samples?
  Liao Xiaoqing,Li Ruiyi,Li Zaijun,Sun Xiulan,Wang Zhouping,Liu Junkang New J. Chem., 2015,39, 5240-5248
• 5. Excellent energy storage performance in NaNbO3-based relaxor antiferroeic ceramics under a low electric field
  XuxinCheng,XiaomingChen,PengyuanFan

• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Benzenesulfonamides

Comprehensive Overview of 1-(4-bromobenzenesulfonyl)-2-methyl-1H-imidazole (CAS No. 324776-97-8)

1-(4-bromobenzenesulfonyl)-2-methyl-1H-imidazole (CAS No. 324776-97-8) is a specialized organic compound that has garnered significant attention in pharmaceutical and chemical research. This compound belongs to the class of sulfonylated imidazole derivatives, which are known for their versatile applications in medicinal chemistry and material science. The presence of both a bromobenzenesulfonyl group and a methyl-imidazole moiety makes it a valuable intermediate for synthesizing more complex molecules.

In recent years, the demand for imidazole-based compounds has surged due to their role in drug discovery, particularly in the development of enzyme inhibitors and antimicrobial agents. Researchers are increasingly exploring the potential of 1-(4-bromobenzenesulfonyl)-2-methyl-1H-imidazole as a building block for designing novel therapeutics. Its unique structural features allow for modifications that can enhance bioavailability and target specificity, addressing key challenges in modern pharmacology.

One of the most frequently searched topics related to this compound is its synthetic pathway. The synthesis of 1-(4-bromobenzenesulfonyl)-2-methyl-1H-imidazole typically involves the sulfonylation of 2-methylimidazole with 4-bromobenzenesulfonyl chloride under controlled conditions. This process highlights the importance of green chemistry principles, as researchers strive to minimize waste and improve yield efficiency. Such methodologies align with the growing emphasis on sustainable chemical practices in the industry.

Another area of interest is the compound's physicochemical properties. With a molecular formula of C₁₀H₉BrN₂O₂S, it exhibits moderate solubility in organic solvents like dimethyl sulfoxide (DMSO) and acetonitrile, making it suitable for various experimental setups. Its stability under ambient conditions further enhances its utility in laboratory settings, a feature often queried by chemists and formulators.

The application of 1-(4-bromobenzenesulfonyl)-2-methyl-1H-imidazole in catalysis is another hot topic. Recent studies suggest its potential as a ligand in transition metal-catalyzed reactions, which are pivotal in constructing complex molecular architectures. This aligns with the broader trend of exploring heterocyclic compounds for catalytic applications, a subject frequently searched in academic databases.

From a commercial perspective, the compound's relevance extends to the agrochemical and material science sectors. Its structural motifs are being investigated for developing crop protection agents and advanced polymers, reflecting the interdisciplinary nature of its applications. This versatility answers common queries about its industrial uses beyond pharmaceuticals.

Quality control and analytical characterization of 1-(4-bromobenzenesulfonyl)-2-methyl-1H-imidazole are critical for ensuring reproducibility in research. Techniques such as high-performance liquid chromatography (HPLC), nuclear magnetic resonance (NMR), and mass spectrometry (MS) are routinely employed to verify purity and structural integrity. These methods are frequently discussed in forums and publications, underscoring their importance in compound validation.

In conclusion, 1-(4-bromobenzenesulfonyl)-2-methyl-1H-imidazole (CAS No. 324776-97-8) represents a compelling case study in the intersection of organic synthesis, drug development, and industrial chemistry. Its multifaceted applications and ongoing research interest make it a compound worth watching in the evolving landscape of chemical innovation.

• 150205-84-8(1H-Imidazole, 1-[(4-methylphenyl)sulfonyl]-2-phenyl-)
• 15728-46-8(2-methyl-1-(4-methylbenzenesulfonyl)-1H-1,3-benzodiazole)
• 155742-58-8(1H-Imidazole-2-methanol, 1-[(4-methylphenyl)sulfonyl]-)
• 152940-76-6(1-(4-bromobenzenesulfonyl)-1H-imidazole)
• 951884-57-4(1-(3-Bromo-5-trifluoromethylphenylsulfonyl)-2-methylimidazole)
• 951884-46-1(1-(2-Bromophenylsulfonyl)-1H-imidazole)
• 46248-01-5(1-(Phenylsulfonyl)-1H-imidazole)
• 155742-57-7(1H-Imidazole-2-carboxaldehyde, 1-[(4-methylphenyl)sulfonyl]-)
• 191982-64-6(1H-Imidazole, 2-(bromomethyl)-1-[(4-methylphenyl)sulfonyl]-)
• 86181-71-7(2-Methyl-1-tosyl-1H-imidazole)