Cas no 32460-08-5 (3,5-dibromofuran-2-carboxylic Acid)

3,5-Dibromofuran-2-carboxylic acid is a brominated furan derivative with significant utility in organic synthesis and pharmaceutical research. Its key advantages include its role as a versatile intermediate in the preparation of heterocyclic compounds, owing to the reactivity of both the carboxylic acid and bromine substituents. The electron-withdrawing effects of the bromine atoms enhance the electrophilic character of the furan ring, facilitating further functionalization. This compound is particularly valuable in cross-coupling reactions and as a precursor for bioactive molecules. Its high purity and stability under standard conditions make it a reliable reagent for advanced chemical applications.
3,5-dibromofuran-2-carboxylic Acid structure
32460-08-5 structure
Product Name:3,5-dibromofuran-2-carboxylic Acid
CAS No:32460-08-5
MF:C5H2Br2O3
MW:269.875580310822
CID:916956
PubChem ID:298441
Update Time:2025-10-28

3,5-dibromofuran-2-carboxylic Acid Chemical and Physical Properties

Names and Identifiers

    • 3,5-dibromofuran-2-carboxylic Acid
    • 3,5-Dibromo-2-furancarboxylic acid
    • 3,5-dibromo-furan-2-carboxylic acid
    • AC1L6T4Z
    • AC1Q721P
    • CTK8I2009
    • NSC170575
    • SureCN6690917
    • NSC 170575
    • 32460-08-5
    • 3,5-dibromofuran-2-carboxylicacid
    • SCHEMBL6690917
    • NSC-170575
    • AKOS024324633
    • 3,5-dibromo-2-furoic acid
    • DTXSID90305374
    • Inchi: 1S/C5H2Br2O3/c6-2-1-3(7)10-4(2)5(8)9/h1H,(H,8,9)
    • InChI Key: XABKAGDBOCDYBJ-UHFFFAOYSA-N
    • SMILES: BrC1C=C(OC=1C(=O)O)Br

Computed Properties

  • Exact Mass: 267.83696
  • Monoisotopic Mass: 267.837
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 10
  • Rotatable Bond Count: 1
  • Complexity: 150
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 2.6
  • Topological Polar Surface Area: 50.4?2

Experimental Properties

  • Density: 2.304±0.06 g/cm3 (20 oC 760 Torr),
  • Boiling Point: 311.2°C at 760 mmHg
  • Flash Point: 142°C
  • Refractive Index: 1.614
  • Solubility: Very slightly soluble (0.7 g/l) (25 o C),
  • PSA: 50.44
  • LogP: 2.50280

3,5-dibromofuran-2-carboxylic Acid Pricemore >>

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Additional information on 3,5-dibromofuran-2-carboxylic Acid

3,5-Dibromofuran-2-Carboxylic Acid: A Comprehensive Overview

3,5-Dibromofuran-2-carboxylic acid (CAS No. 32460-08-5) is a highly specialized organic compound with significant applications in various fields of chemistry and materials science. This compound is characterized by its unique structure, which includes a furan ring substituted with two bromine atoms at the 3 and 5 positions and a carboxylic acid group at the 2 position. The combination of these functional groups makes it a versatile building block for synthesizing advanced materials and compounds.

The synthesis of 3,5-dibromofuran-2-carboxylic acid has been extensively studied, with researchers exploring various methodologies to optimize its production. Recent advancements in catalytic systems and reaction conditions have enabled the synthesis of this compound with high purity and yield. For instance, studies have demonstrated the use of microwave-assisted synthesis to accelerate the reaction process while maintaining the integrity of the functional groups. Such innovations are crucial for scaling up production to meet industrial demands.

One of the most notable applications of 3,5-dibromofuran-2-carboxylic acid is in the field of materials science, particularly in the development of advanced polymers and composites. The bromine atoms in the molecule serve as reactive sites for polymerization reactions, enabling the creation of materials with tailored mechanical and thermal properties. Recent research has highlighted its potential in synthesizing high-performance polymers for use in aerospace and automotive industries, where lightweight yet durable materials are highly sought after.

In addition to its role in polymer chemistry, 3,5-dibromofuran-2-carboxylic acid has found applications in pharmaceutical research. The carboxylic acid group provides a platform for further functionalization, allowing researchers to design molecules with specific biological activities. For example, studies have explored its use as a precursor for anti-inflammatory agents and anticancer drugs. The ability to modify the molecule's structure while retaining its core functionality has made it a valuable asset in drug discovery.

The environmental impact of 3,5-dibromofuran-2-carboxylic acid has also been a topic of recent research interest. Scientists are investigating methods to minimize waste generation during its synthesis and maximize its recycling potential. Green chemistry approaches, such as using biodegradable solvents and reducing energy consumption during production, are being implemented to ensure sustainable manufacturing practices.

Furthermore, 3,5-dibromofuran-2-carboxylic acid plays a significant role in analytical chemistry as a reference standard for chromatographic separations. Its distinct chemical properties make it an ideal compound for calibrating instruments used in quality control processes across various industries.

In conclusion, 3,5-dibromofuran-2-carboxylic acid (CAS No. 32460-08-5) is a multifaceted compound with diverse applications across multiple disciplines. Its unique structure and functional groups make it an invaluable tool for researchers and industry professionals alike. As advancements in synthetic methods and material science continue to unfold, the potential uses of this compound are expected to expand further, solidifying its position as a key player in modern chemistry.

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