Cas no 32428-61-8 (2-chloro-N-(3-methylphenyl)acetamide)

2-Chloro-N-(3-methylphenyl)acetamide is a chloroacetamide derivative with the molecular formula C?H??ClNO. This compound is characterized by its chloroacetyl group bonded to a 3-methylaniline moiety, making it a versatile intermediate in organic synthesis. It is particularly useful in the preparation of pharmaceuticals, agrochemicals, and specialty chemicals due to its reactivity as an electrophile. The presence of the chloro substituent enhances its utility in nucleophilic substitution reactions, while the methylphenyl group contributes to its solubility in organic solvents. The compound is typically handled under controlled conditions due to its potential reactivity. Its stability and well-defined structure make it a reliable reagent for targeted synthetic applications.
2-chloro-N-(3-methylphenyl)acetamide structure
32428-61-8 structure
Product Name:2-chloro-N-(3-methylphenyl)acetamide
CAS No:32428-61-8
MF:C9H10ClNO
MW:183.634801387787
MDL:MFCD00018901
CID:316356
PubChem ID:296325
Update Time:2025-11-02

2-chloro-N-(3-methylphenyl)acetamide Chemical and Physical Properties

Names and Identifiers

    • 2-Chloro-N-(m-tolyl)acetamide
    • 2-Chloro-N-(3-methylphenyl)acetamide
    • Acetamide,2-chloro-N-(3-methylphenyl)-
    • [(3-methylphenyl)aminocarbonylmethyl]chloride
    • 2-chloro-N-m-tolylacetamide
    • Acetamide,2-chloro-N-(3-methylphenyl)
    • Acetamide,N-(3-methylphenyl)-2-chloro
    • N-(3-methylphenyl)-2-chloroacetamide
    • N-(3-methylphenyl)chloroacetamide
    • 10.14272/GYMACIQGUHXSLT-UHFFFAOYSA-N.1
    • MFCD00018901
    • LS-01168
    • F9995-0366
    • BB 0217602
    • Acetamide, N-(3-methylphenyl)-2-chloro-
    • NSC166401
    • Z56862383
    • DTXSID70304587
    • 10.14272/GYMACIQGUHXSLT-UHFFFAOYSA-N
    • AB00807018-03
    • AKOS000268725
    • FT-0678538
    • Chloracetyl-m-toluidin
    • 2-Chloro-N-m-tolyl-acetamide
    • Acetamide, 2-chloro-N-(3-methylphenyl)-
    • AB00807018-04
    • NCGC00331416-01
    • NCI60_001296
    • doi:10.14272/GYMACIQGUHXSLT-UHFFFAOYSA-N.1
    • 2-Chloro-N-(m-tolyl d7)acetamide
    • 32428-61-8
    • NSC-166401
    • CHEMBL1998563
    • SCHEMBL4005968
    • A1-48105
    • EN300-01519
    • doi:10.14272/GYMACIQGUHXSLT-UHFFFAOYSA-N
    • G67686
    • ALBB-002259
    • STK117233
    • DB-028019
    • 2-chloro-N-(3-methylphenyl)acetamide
    • MDL: MFCD00018901
    • Inchi: 1S/C9H10ClNO/c1-7-3-2-4-8(5-7)11-9(12)6-10/h2-5H,6H2,1H3,(H,11,12)
    • InChI Key: GYMACIQGUHXSLT-UHFFFAOYSA-N
    • SMILES: ClCC(NC1C=CC=C(C)C=1)=O

Computed Properties

  • Exact Mass: 183.04500
  • Monoisotopic Mass: 183.045
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 12
  • Rotatable Bond Count: 3
  • Complexity: 161
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 2.3
  • Topological Polar Surface Area: 29.1A^2

Experimental Properties

  • Density: 1.222
  • Boiling Point: 338.5°Cat760mmHg
  • Flash Point: 158.5°C
  • Refractive Index: 1.583
  • PSA: 29.10000
  • LogP: 2.24530

2-chloro-N-(3-methylphenyl)acetamide Security Information

2-chloro-N-(3-methylphenyl)acetamide Customs Data

  • HS CODE:2924299090
  • Customs Data:

    China Customs Code:

    2924299090

    Overview:

    2924299090. Other cyclic amides(Including cyclic carbamates)(Including their derivatives as well as their salts). VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to, packing

    Summary:

    2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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2-chloro-N-(3-methylphenyl)acetamide Suppliers

Amadis Chemical Company Limited
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(CAS:32428-61-8)2-chloro-N-(3-methylphenyl)acetamide
Order Number:A875624
Stock Status:in Stock
Quantity:25g
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 09:46
Price ($):412.0

Additional information on 2-chloro-N-(3-methylphenyl)acetamide

Exploring the Properties and Applications of 2-Chloro-N-(3-Methylphenyl)Acetamide (CAS No. 32428-61-8)

2-Chloro-N-(3-methylphenyl)acetamide (CAS No. 32428-61-8) is a specialized chemical compound that has garnered attention in various industrial and research applications. This article delves into its chemical properties, synthesis methods, applications, and market relevance, while addressing frequently searched questions related to this compound.

The molecular structure of 2-chloro-N-(3-methylphenyl)acetamide consists of a chloro-substituted acetamide group attached to a 3-methylphenyl ring. This unique configuration contributes to its distinct physicochemical properties, making it valuable in organic synthesis and material science. Researchers often explore its reactivity in amide bond formation and aryl substitution reactions, which are trending topics in green chemistry discussions.

One of the most searched questions about CAS 32428-61-8 relates to its solubility characteristics. Studies indicate that this compound demonstrates moderate solubility in polar organic solvents like ethanol and acetone, but limited solubility in water. This property profile makes it particularly useful in pharmaceutical intermediates development, where controlled solubility is often required for drug formulation processes.

In recent years, the application of 2-chloro-N-(3-methylphenyl)acetamide in agrochemical research has become a significant area of interest. Its structural features show potential in the development of novel plant protection agents, aligning with current global trends in sustainable agriculture. The compound's ability to serve as a building block for more complex molecules has positioned it as a valuable asset in crop science innovations.

The thermal stability of 32428-61-8 makes it suitable for various industrial processes. With a decomposition temperature typically above 200°C, it can withstand many common reaction conditions without significant degradation. This characteristic is particularly important for researchers investigating high-temperature synthesis methods, a frequently searched topic in chemical engineering forums.

From a commercial perspective, the global market for 2-chloro-N-(3-methylphenyl)acetamide has shown steady growth, driven by increasing demand from the specialty chemicals sector. Suppliers often highlight its purity grades (typically 97-99%) and packaging options in product listings, addressing common procurement queries from potential buyers.

Environmental considerations surrounding CAS 32428-61-8 have become more prominent in user searches. Current research indicates that proper handling and disposal methods should be followed, in line with standard laboratory safety protocols. The compound's biodegradation profile and ecotoxicological data are subjects of ongoing study, reflecting the chemical industry's growing emphasis on environmental impact assessment.

Analytical methods for 2-chloro-N-(3-methylphenyl)acetamide characterization frequently appear in search queries. Common techniques include HPLC for purity analysis, GC-MS for identification, and NMR spectroscopy for structural confirmation. These methods are crucial for quality control in both research and industrial settings, particularly for users concerned about compound authentication.

The future outlook for 32428-61-8 appears promising, with potential applications emerging in material science and advanced polymer chemistry. Its molecular architecture offers opportunities for creating novel functional materials, a topic gaining traction in scientific literature and patent filings. Researchers are particularly interested in its possible role in developing smart materials with responsive properties.

Storage recommendations for 2-chloro-N-(3-methylphenyl)acetamide typically suggest keeping the compound in a cool, dry environment away from direct sunlight. These conditions help maintain its stability over extended periods, addressing common storage-related questions from laboratory personnel and industrial users alike.

In conclusion, 2-chloro-N-(3-methylphenyl)acetamide (CAS No. 32428-61-8) represents an important chemical entity with diverse applications across multiple scientific disciplines. Its unique properties continue to inspire research and development efforts, particularly in areas aligned with current technological and environmental trends. As understanding of this compound deepens, its role in advancing various fields of chemistry and materials science is likely to expand further.

Recommended suppliers
Amadis Chemical Company Limited
(CAS:32428-61-8)2-chloro-N-(3-methylphenyl)acetamide
A875624
Purity:99%
Quantity:25g
Price ($):412.0
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