Cas no 324028-87-7 (Methyl 5,6-dimethoxypicolinate)

Methyl 5,6-dimethoxypicolinate is a versatile intermediate in organic synthesis, particularly valued for its role in the preparation of pharmaceuticals and agrochemicals. The compound features a picolinate core substituted with methoxy groups at the 5 and 6 positions, enhancing its reactivity and selectivity in cross-coupling and functionalization reactions. Its ester functionality allows for further derivatization, making it a useful building block for heterocyclic compounds. The dimethoxy substitution pattern contributes to improved solubility and stability, facilitating handling and storage. This compound is commonly employed in the synthesis of bioactive molecules, including kinase inhibitors and other therapeutic agents, due to its reliable performance and compatibility with diverse reaction conditions.
Methyl 5,6-dimethoxypicolinate structure
324028-87-7 structure
Product Name:Methyl 5,6-dimethoxypicolinate
CAS No:324028-87-7
MF:C9H11NO4
MW:197.187942743301
MDL:MFCD11857720
CID:853860
PubChem ID:329771640
Update Time:2025-06-13

Methyl 5,6-dimethoxypicolinate Chemical and Physical Properties

Names and Identifiers

    • Methyl 5,6-dimethoxypicolinate
    • A-6434
    • AC1Q43RR
    • AG-B-28114
    • CTK6I9810
    • SureCN7226331
    • Methyl5,6-dimethoxypicolinate
    • MFCD11857720
    • Y13491
    • 324028-87-7
    • ZMA02887
    • methyl 5,6-dimethoxypyridine-2-carboxylate
    • DB-068622
    • DTXSID20673912
    • Methyl 5,6-dimethoxypicolinate, AldrichCPR
    • SCHEMBL7226331
    • AKOS006345059
    • MDL: MFCD11857720
    • Inchi: 1S/C9H11NO4/c1-12-7-5-4-6(9(11)14-3)10-8(7)13-2/h4-5H,1-3H3
    • InChI Key: PVGFGXWPUXNVFR-UHFFFAOYSA-N
    • SMILES: O(C)C1=CC=C(C(=O)OC)N=C1OC

Computed Properties

  • Exact Mass: 197.06880783g/mol
  • Monoisotopic Mass: 197.06880783g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 5
  • Heavy Atom Count: 14
  • Rotatable Bond Count: 4
  • Complexity: 197
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 1.3
  • Topological Polar Surface Area: 57.6?2

Methyl 5,6-dimethoxypicolinate Security Information

  • Symbol: GHS05
  • Signal Word:Danger
  • Hazard Statement: H318
  • Warning Statement: P280-P305+P351+P338
  • Hazardous Material transportation number:NONH for all modes of transport
  • WGK Germany:3
  • Hazard Category Code: 41
  • Safety Instruction: 26-39
  • Hazardous Material Identification: Xi
  • HazardClass:IRRITANT

Methyl 5,6-dimethoxypicolinate Pricemore >>

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Methyl 5,6-dimethoxypicolinate Related Literature

Additional information on Methyl 5,6-dimethoxypicolinate

Comprehensive Overview of Methyl 5,6-dimethoxypicolinate (CAS No. 324028-87-7): Properties, Applications, and Industry Insights

Methyl 5,6-dimethoxypicolinate (CAS No. 324028-87-7) is a specialized organic compound belonging to the picolinate ester family. This compound has garnered significant attention in pharmaceutical and agrochemical research due to its unique structural features, including the presence of two methoxy groups at the 5 and 6 positions of the pyridine ring. With the growing demand for heterocyclic building blocks in drug discovery, Methyl 5,6-dimethoxypicolinate serves as a versatile intermediate for synthesizing bioactive molecules.

The compound's molecular formula (C9H11NO4) and molecular weight (197.19 g/mol) make it suitable for applications requiring precise molecular design. Researchers often explore its potential in developing kinase inhibitors and antioxidant agents, aligning with current trends in targeted therapy and oxidative stress management. Its solubility in organic solvents like DMSO and methanol further enhances its utility in laboratory settings.

In the context of green chemistry, Methyl 5,6-dimethoxypicolinate is studied for its role in sustainable synthesis routes. The compound's stability under mild conditions makes it a candidate for catalytic reactions and flow chemistry—two areas gaining traction in industrial optimization. Recent publications highlight its use in multi-step synthesis of complex molecules, addressing the need for cost-effective methodologies.

From an analytical perspective, CAS No. 324028-87-7 is characterized by techniques such as NMR spectroscopy and high-resolution mass spectrometry (HRMS). These methods confirm its purity, a critical factor for pharmaceutical-grade intermediates. Users frequently search for "Methyl 5,6-dimethoxypicolinate synthesis" or "buy Methyl 5,6-dimethoxypicolinate," reflecting its commercial relevance. Suppliers often provide technical data sheets (TDS) detailing its storage conditions (typically 2–8°C) and handling precautions.

The compound's potential extends to material science, where its aromatic system contributes to the development of organic electronic materials. With the rise of flexible electronics, researchers investigate derivatives of Methyl 5,6-dimethoxypicolinate for charge transport properties. This interdisciplinary appeal positions it as a compound of interest beyond traditional chemistry sectors.

Regulatory compliance is another key consideration. While Methyl 5,6-dimethoxypicolinate is not classified as hazardous under major chemical inventories like REACH or TSCA, proper risk assessment protocols are recommended during handling. FAQs such as "Is Methyl 5,6-dimethoxypicolinate biodegradable?" or "What are the alternatives to Methyl 5,6-dimethoxypicolinate?" indicate user interest in environmental and substitution strategies.

In summary, Methyl 5,6-dimethoxypicolinate (CAS No. 324028-87-7) exemplifies the convergence of synthetic utility and research innovation. Its applications span pharmaceuticals, agrochemicals, and advanced materials, making it a valuable asset for scientists addressing global challenges in health and sustainability. As demand for tailor-made intermediates grows, this compound will likely remain a focal point in chemical R&D pipelines.

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