Cas no 3234-51-3 ((2,2-dibromocyclopropyl)benzene)

(2,2-Dibromocyclopropyl)benzene is a brominated cyclopropane derivative with a phenyl substituent, serving as a versatile intermediate in organic synthesis. Its key structural features—the highly strained cyclopropane ring and reactive dibromo moiety—make it valuable for cyclopropanation reactions, ring-opening transformations, and cross-coupling processes. The compound is particularly useful in the synthesis of pharmaceuticals, agrochemicals, and functionalized aromatic systems due to its ability to act as a precursor for cyclopropyl anions or radicals. Its stability under controlled conditions allows for precise functionalization, while the dibromo group offers selective reactivity for further derivatization. The product is typically handled under inert conditions to preserve its reactivity.
(2,2-dibromocyclopropyl)benzene structure
3234-51-3 structure
Product Name:(2,2-dibromocyclopropyl)benzene
CAS No:3234-51-3
MF:C9H8Br2
MW:275.967821121216
MDL:MFCD00464690
CID:1450588
PubChem ID:220379
Update Time:2025-06-12

(2,2-dibromocyclopropyl)benzene Chemical and Physical Properties

Names and Identifiers

    • (2,2-dibromocyclopropyl)benzene
    • Benzene, (2,2-dibromocyclopropyl)-
    • ghl.PD_Mitscher_leg0.1031
    • AC1Q26IK
    • 2,2-dibromocyclopropylbenzene
    • 1-(2,2-dibromocyclopropyl)benzene
    • AGN-PC-0062R6
    • (2,2-dibromocyclopropyl)-benzene
    • 1-Phenyl-2,2-dibromo-cyclopropane
    • AC1L58PL
    • NSC3014
    • 1-bromo-2-phenylcyclopropane
    • 2-phenyl-1,1-dibromocyclopropane
    • 1,1-dibromo-2-phenylcyclopropane
    • SureCN1854233
    • (2,2-Dibromocyclopropyl)benzene #
    • SCHEMBL1854233
    • AKOS024406400
    • NSC72310
    • DTXSID20277595
    • MFCD00464690
    • 3234-51-3
    • NSC-3014
    • NSC-72310
    • DA-32178
    • MDL: MFCD00464690
    • Inchi: 1S/C9H8Br2/c10-9(11)6-8(9)7-4-2-1-3-5-7/h1-5,8H,6H2
    • InChI Key: RRSAMRMQHHYSGN-UHFFFAOYSA-N
    • SMILES: BrC1(CC1C1C=CC=CC=1)Br

Computed Properties

  • Exact Mass: 273.89924
  • Monoisotopic Mass: 273.89928g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 0
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 1
  • Complexity: 148
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 1
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 3.6
  • Topological Polar Surface Area: 0?2

Experimental Properties

  • PSA: 0
  • LogP: 3.66000

(2,2-dibromocyclopropyl)benzene Pricemore >>

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(2,2-dibromocyclopropyl)benzene Suppliers

Amadis Chemical Company Limited
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(CAS:3234-51-3)(2,2-dibromocyclopropyl)benzene
Order Number:A1153366
Stock Status:in Stock
Quantity:1g/5g
Purity:99%
Pricing Information Last Updated:Thursday, 29 August 2024 23:20
Price ($):290.0/646.0

Additional information on (2,2-dibromocyclopropyl)benzene

Comprehensive Overview of (2,2-Dibromocyclopropyl)benzene (CAS No. 3234-51-3): Properties, Applications, and Industry Insights

(2,2-Dibromocyclopropyl)benzene (CAS No. 3234-51-3) is a specialized organic compound that has garnered significant attention in recent years due to its unique structural features and versatile applications. This brominated cyclopropane derivative, characterized by a benzene ring attached to a dibromocyclopropyl group, is widely studied in synthetic chemistry and material science. Its molecular formula, C9H8Br2, reflects a high degree of reactivity, making it valuable for cross-coupling reactions, pharmaceutical intermediates, and advanced material synthesis.

The compound's thermal stability and electrophilic properties have made it a subject of interest for researchers exploring green chemistry alternatives and sustainable synthesis routes. With increasing global focus on eco-friendly chemical processes, (2,2-dibromocyclopropyl)benzene is often discussed in the context of catalyst optimization and waste reduction. Its role in high-efficiency organic transformations aligns with the industry's shift toward atom economy and renewable feedstocks.

One of the most searched questions regarding this compound is: "What are the applications of (2,2-dibromocyclopropyl)benzene in agrochemicals?" Studies reveal its potential as a precursor for crop protection agents, where its cyclopropyl moiety contributes to bioactivity. Additionally, its derivatives are investigated for polymer additives and flame retardants, addressing the growing demand for non-toxic material enhancers.

From a safety and handling perspective, CAS No. 3234-51-3 requires standard laboratory precautions, including the use of personal protective equipment (PPE) and ventilated workspaces. While not classified as hazardous under normal conditions, its bromine content necessitates careful storage away from reactive metals. Recent patent literature highlights innovations in its large-scale production, emphasizing cost-effective purification methods.

In the pharmaceutical sector, this compound serves as a building block for chiral ligands and bioactive molecules. Its rigid cyclopropyl structure is particularly useful in medicinal chemistry for designing enzyme inhibitors. The rise of AI-driven drug discovery has further amplified interest in such scaffolds, with computational studies predicting their binding affinities.

Environmental considerations are another hot topic tied to (2,2-dibromocyclopropyl)benzene. Researchers are evaluating its biodegradability and environmental persistence, especially in water treatment systems. Regulatory agencies increasingly scrutinize brominated compounds, prompting the development of analytical detection techniques like GC-MS and HPLC.

For those sourcing CAS 3234-51-3, key factors include purity grades (e.g., >98% for research vs. >95% for industrial use) and supply chain transparency. The compound's global market trends show steady growth, driven by demand from Asia-Pacific chemical hubs. Analytical certificates (CoA) often detail parameters like melting point (≈85°C) and solubility profiles (soluble in THF, DCM).

Emerging applications in electronic materials are also noteworthy. The benzene-dibromocyclopropane hybrid structure shows promise in organic semiconductors and photoresist formulations, coinciding with the miniaturization trend in electronics. This positions 3234-51-3 as a candidate for next-gen flexible displays and printed circuits.

In summary, (2,2-dibromocyclopropyl)benzene exemplifies the convergence of traditional organic synthesis and cutting-edge technology. Its multifaceted utility—from drug development to smart materials—ensures its relevance in an evolving chemical landscape. Ongoing research continues to uncover novel derivatives, reinforcing its status as a high-value intermediate.

Recommended suppliers
Amadis Chemical Company Limited
(CAS:3234-51-3)(2,2-dibromocyclopropyl)benzene
A1153366
Purity:99%/99%
Quantity:1g/5g
Price ($):290.0/646.0
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