• 1. Essential effect of the electrolyte on the mechanical and chemical degradation of LiNi0.8Co0.15Al0.05O2 cathodes upon long-term cycling??
  Xiaoming Liu,Zachary D. Hood,Wangda Li,Donovan N. Leonard,Arumugam Manthiram,Miaofang Chi J. Mater. Chem. A, 2021,9, 2111-2119
• 2. Emerging investigator series: first-principles and thermodynamics comparison of compositionally-tuned delafossites: cation release from the (001) surface of complex metal oxides?
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• 3. Evolution of calcium phosphate precipitation in hanging drop vapor diffusion by in situRaman microspectroscopy
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• Solvents and Organic Chemicals Organic Compounds Benzenoids Phenols Halophenols Bromophenols

4-Bromo-3-(2-hydroxyethyl)phenol (CAS No. 319473-28-4): A Comprehensive Overview

4-Bromo-3-(2-hydroxyethyl)phenol (CAS No. 319473-28-4) is a brominated phenolic compound with a wide range of applications in organic synthesis, pharmaceuticals, and specialty chemicals. This compound, also known as 4-bromo-3-(2-hydroxyethyl)phenol, features a hydroxyl group and a bromine atom attached to a benzene ring, making it a versatile intermediate in chemical reactions. Its unique structure allows it to participate in various coupling reactions, substitutions, and polymerizations, making it valuable in both academic research and industrial applications.

The chemical properties of 4-bromo-3-(2-hydroxyethyl)phenol include a molecular weight of 217.06 g/mol and a melting point range that varies depending on purity. The presence of the hydroxyethyl group enhances its solubility in polar solvents such as water, ethanol, and methanol, while the bromine substituent increases its reactivity in electrophilic aromatic substitution reactions. Researchers often utilize this compound in the synthesis of more complex molecules, including bioactive compounds and advanced materials.

One of the most common applications of 4-bromo-3-(2-hydroxyethyl)phenol is in pharmaceutical research, where it serves as a key intermediate in the development of drug candidates. Its structural motif is found in several therapeutic agents, particularly those targeting inflammation and microbial infections. Additionally, this compound is used in the production of specialty polymers and resins, where its reactive sites allow for cross-linking and modification of material properties.

Recent trends in chemical research highlight the growing interest in brominated phenolic compounds due to their potential in green chemistry and sustainable synthesis. Scientists are exploring eco-friendly methods to produce 4-bromo-3-(2-hydroxyethyl)phenol using catalytic processes that minimize waste and reduce hazardous byproducts. This aligns with the broader industry shift toward environmentally responsible chemical manufacturing.

From an industrial perspective, the demand for 4-bromo-3-(2-hydroxyethyl)phenol is driven by its role in high-value chemical synthesis. Manufacturers are optimizing production processes to improve yield and purity, ensuring consistent supply for research and commercial applications. Quality control measures, such as HPLC and NMR analysis, are critical in verifying the compound's specifications before distribution.

In the context of SEO optimization, users frequently search for terms like "4-bromo-3-(2-hydroxyethyl)phenol uses," "CAS 319473-28-4 suppliers," and "brominated phenol synthesis." Addressing these queries, this article provides detailed insights into the compound's applications, sourcing, and synthetic pathways. Additionally, researchers often seek information on "safe handling of brominated compounds" and "alternative synthesis methods," which are covered in this discussion.

Another emerging area of interest is the use of 4-bromo-3-(2-hydroxyethyl)phenol in materials science, particularly in the development of conductive polymers and coatings. Its ability to undergo polymerization and functionalization makes it a candidate for advanced electronic materials. This aligns with current trends in nanotechnology and smart materials, where researchers are exploring novel building blocks for next-generation devices.

For laboratories and chemical suppliers, proper storage and handling of 4-bromo-3-(2-hydroxyethyl)phenol are essential to maintain stability and prevent degradation. Recommendations include storing the compound in a cool, dry place, away from direct sunlight and incompatible substances. Safety data sheets (SDS) provide detailed guidelines for handling, ensuring compliance with regulatory standards.

In summary, 4-bromo-3-(2-hydroxyethyl)phenol (CAS No. 319473-28-4) is a multifaceted compound with significant applications in pharmaceuticals, materials science, and specialty chemicals. Its unique structural features and reactivity make it a valuable tool for researchers and manufacturers alike. As the chemical industry continues to evolve, this compound is likely to play an increasingly important role in sustainable and innovative applications.

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