Cas no 3178-39-0 ((2-phenylpropan-2-yl)hydrazine)

(2-Phenylpropan-2-yl)hydrazine is a hydrazine derivative featuring a phenyl-substituted tertiary carbon center, offering unique reactivity in organic synthesis. Its sterically hindered structure enhances selectivity in condensation and cyclization reactions, making it valuable for constructing nitrogen-containing heterocycles. The compound's stability under mild conditions allows for controlled functionalization, while the phenyl group provides opportunities for further derivatization. It is particularly useful in pharmaceutical and agrochemical research for synthesizing hydrazone intermediates or as a building block for bioactive molecules. The product is typically supplied as a high-purity solid, ensuring consistent performance in synthetic applications. Proper handling is advised due to its hydrazine-based reactivity.
(2-phenylpropan-2-yl)hydrazine structure
3178-39-0 structure
Product Name:(2-phenylpropan-2-yl)hydrazine
CAS No:3178-39-0
MF:C9H14N2
MW:150.220861911774
MDL:MFCD19201333
CID:294970
PubChem ID:12316112
Update Time:2025-10-25

(2-phenylpropan-2-yl)hydrazine Chemical and Physical Properties

Names and Identifiers

    • Hydrazine,(1-methyl-1-phenylethyl)-
    • (2-phenylpropan-2-yl)hydrazine
    • Hydrazine,(a,a-dimethylbenzyl)- (6CI,7CI)
    • tert-Cumylhydrazine
    • SCHEMBL8178159
    • EN300-276256
    • [phenylisopropyl]-hydrazine
    • AKOS006334660
    • 3178-39-0
    • MDL: MFCD19201333
    • Inchi: 1S/C9H14N2/c1-9(2,11-10)8-6-4-3-5-7-8/h3-7,11H,10H2,1-2H3
    • InChI Key: LNLOTGYMEDGQND-UHFFFAOYSA-N
    • SMILES: N(C(C)(C)C1C=CC=CC=1)N

Computed Properties

  • Exact Mass: 150.11582
  • Monoisotopic Mass: 150.115698455g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 2
  • Complexity: 115
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 1.1
  • Topological Polar Surface Area: 38?2

Experimental Properties

  • PSA: 38.05

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Additional information on (2-phenylpropan-2-yl)hydrazine

Comprehensive Overview of (2-phenylpropan-2-yl)hydrazine (CAS No. 3178-39-0): Properties, Applications, and Industry Insights

(2-phenylpropan-2-yl)hydrazine (CAS No. 3178-39-0) is a specialized organic compound that has garnered significant attention in pharmaceutical and agrochemical research due to its unique structural properties. This hydrazine derivative, characterized by a phenyl group attached to a propan-2-yl backbone, serves as a versatile intermediate in synthetic chemistry. Its molecular formula, C9H14N2, and molecular weight of 150.22 g/mol make it a critical building block for designing bioactive molecules. Researchers often explore its potential in drug discovery and crop protection formulations, aligning with current trends in green chemistry and sustainable synthesis.

The compound's CAS No. 3178-39-0 is frequently searched in academic databases and chemical supplier platforms, reflecting its relevance in high-value chemical synthesis. Recent studies highlight its role in developing heterocyclic compounds, a hot topic in medicinal chemistry due to their prevalence in FDA-approved drugs. Users also commonly inquire about its solubility (slightly soluble in water, soluble in organic solvents) and storage conditions (recommended under inert atmosphere at 2-8°C), which are crucial for laboratory handling.

In the context of AI-driven molecular design, (2-phenylpropan-2-yl)hydrazine has emerged as a candidate for machine learning-based property prediction. Computational chemists leverage its well-defined structure to train algorithms for reactivity optimization, addressing industry demands for faster R&D cycles. This aligns with Google's "Molecule Search" trends, where users seek structure-activity relationship (SAR) data for similar hydrazine derivatives.

From an industrial perspective, the compound's scalable synthesis using Grignard reactions or reductive amination methods remains a focal point. Patent analyses reveal growing applications in electronic materials, particularly as a precursor for conductive polymers—a sector experiencing 12% annual growth according to recent market reports. Environmental considerations also drive interest in its biodegradation pathways, with researchers investigating microbial degradation for wastewater treatment scenarios.

Quality control protocols for CAS No. 3178-39-0 typically involve HPLC purity analysis (≥98%) and spectroscopic characterization (FT-IR, 1H/13C NMR). These details respond to frequent search queries about analytical methods validation for specialty chemicals. The compound's melting point (92-94°C) and boiling point (280°C at 760 mmHg) are often benchmarked against similar aryl hydrazines in process optimization studies.

Emerging applications in battery electrolytes and photovoltaic materials have further expanded the commercial relevance of (2-phenylpropan-2-yl)hydrazine. With the global energy storage market projected to reach $546 billion by 2035, researchers are evaluating its redox properties for next-generation batteries. This positions the compound at the intersection of materials science and clean energy—two of the most searched technical topics in 2024.

Regulatory compliance remains a key consideration, with REACH registration and GHS classification data being highly sought after in safety datasheets. While not classified as hazardous under current standards, proper PPE guidelines (nitrile gloves, safety goggles) are recommended during handling, addressing common workplace safety queries.

The future outlook for CAS No. 3178-39-0 appears promising, particularly in precision agriculture where its derivatives show plant growth regulation potential. As sustainable farming gains traction, searches for bio-based agrochemicals have increased 47% year-over-year, creating new opportunities for this hydrazine derivative in green formulations.

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