Cas no 3164-06-5 (3-(Benzo[d]oxazol-2-yl)phenol)
3-(Benzo[d]oxazol-2-yl)phenol Chemical and Physical Properties
Names and Identifiers
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- 3-(Benzo[d]oxazol-2-yl)phenol
- 3-(benzo[d]oxazol-2-yl)phenol; I14-11690; 3-benzooxazol-2-yl-phenol; AGN-PC-00L44N; 3-benzo[d]oxazol-2-yl-phenol; 2-(3'-hydroxyphenyl)benzothiazole; AK128254; CHEMBL252155; KB-233438; SureCN3013427; 3-(2-Benzoxazolyl)-phenol; AKOS015899945; 3-benzoxazol-2-yl-phenol; 2-< 3-Hydroxy-phenyl> -benzoxzol; Phenol, 3-(2-benzoxazolyl)-;
- QHUYLIOMTFQOSN-UHFFFAOYSA-N
- 3164-06-5
- 3-benzooxazol-2-yl-phenol
- 3-(1,3-Benzoxazol-2-yl)phenol
- DTXSID00521386
- AKOS015899945
- SCHEMBL3013427
- 2-(3-Hydroxyphenyl)-benzoxazol
- CHEMBL252155
- DA-19105
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- Inchi: 1S/C13H9NO2/c15-10-5-3-4-9(8-10)13-14-11-6-1-2-7-12(11)16-13/h1-8,15H
- InChI Key: QHUYLIOMTFQOSN-UHFFFAOYSA-N
- SMILES: O1C2C=CC=CC=2N=C1C1C=CC=C(C=1)O
Computed Properties
- Exact Mass: 211.06337
- Monoisotopic Mass: 211.063328530g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 3
- Heavy Atom Count: 16
- Rotatable Bond Count: 1
- Complexity: 246
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 3.1
- Topological Polar Surface Area: 46.3?2
Experimental Properties
- PSA: 46.26
3-(Benzo[d]oxazol-2-yl)phenol Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Chemenu | CM154552-1g |
3-(benzo[d]oxazol-2-yl)phenol |
3164-06-5 | 95% | 1g |
$729 | 2021-06-09 | |
| Chemenu | CM154552-1g |
3-(benzo[d]oxazol-2-yl)phenol |
3164-06-5 | 95% | 1g |
$*** | 2023-03-31 | |
| Ambeed | A692598-1g |
3-(Benzo[d]oxazol-2-yl)phenol |
3164-06-5 | 95+% | 1g |
$628.0 | 2024-08-03 |
3-(Benzo[d]oxazol-2-yl)phenol Related Literature
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Ana G. Neo,Ana Bornadiego,Jesús Díaz,Stefano Marcaccini,Carlos F. Marcos Org. Biomol. Chem., 2013,11, 6546-6555
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Peiyuan Zeng,Xiaoxiao Wang,Ming Ye,Qiuyang Ma,Jianwen Li,Wanwan Wang,Baoyou Geng,Zhen Fang RSC Adv., 2016,6, 23074-23084
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Kay S. McMillan,Anthony G. McCluskey,Annette Sorensen,Marie Boyd,Michele Zagnoni Analyst, 2016,141, 100-110
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Ji-Ping Wei Nanoscale, 2015,7, 11815-11832
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Jacob S. Jordan,Evan R. Williams Analyst, 2021,146, 2617-2625
Additional information on 3-(Benzo[d]oxazol-2-yl)phenol
3-(Benzo[d]oxazol-2-yl)phenol: A Comprehensive Overview
The compound 3-(Benzo[d]oxazol-2-yl)phenol is a fascinating molecule that has garnered significant attention in the field of biomedical research. Known by its CAS registry number, 3164-06-5, this compound belongs to a class of benzoxazole derivatives, which are known for their diverse pharmacological activities. Benzoxazoles are heterocyclic compounds that combine the structural features of benzene and oxazole rings, making them highly versatile in drug discovery.
Recent studies have highlighted the potential of 3-(Benzo[d]oxazol-2-yl)phenol in various biomedical applications. Its unique structure, featuring a phenol group attached to a benzo[d]oxazol ring, contributes to its anti-inflammatory and antioxidant properties. These attributes make it a promising candidate for the development of therapeutic agents targeting oxidative stress-related diseases.
The synthesis of 3-(Benzo[d]oxazol-2-yl)phenol is a well-established process, often involving nucleophilic substitutions and coupling reactions. The molecule's stability and solubility in aqueous media further enhance its suitability for in vitro and in vivo studies. Researchers have explored its applications in cancer chemotherapy, where it has shown selective cytotoxicity against various cancer cell lines.
In the realm of neurodegenerative diseases, 3-(Benzo[d]oxazol-2-yl)phenol has demonstrated potent acetylcholinesterase inhibitory activity, making it a potential candidate for treating Alzheimer's disease. Its ability to cross the blood-brain barrier and exhibit minimal toxicity further underscores its therapeutic potential in this domain.
Recent advancements in molecular modeling and drug delivery systems have enabled researchers to optimize the bioavailability of 3-(Benzo[d]oxazol-2-yl)phenol. For instance, the incorporation of nanoparticle-based delivery has significantly improved its pharmacokinetics, allowing for sustained drug release and enhanced therapeutic efficacy.
Moreover, studies have focused on the safety profile of this compound. Preclinical trials have indicated that it exhibits minimal adverse effects, even at higher doses. This favorable safety profile positions it as a highly promising candidate for further clinical exploration.
In conclusion, 3-(Benzo[d]oxazol-2-yl)phenol represents an exciting frontier in the field of biomedical science. Its unique structural features, coupled with its diverse pharmacological activities, make it a valuable tool for drug development. As research continues to unravel its full potential, this compound is poised to play a significant role in addressing some of the most challenging diseases of our time.
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