• 1. Emerging investigator series: heterogeneous reactions of sulfur dioxide on mineral dust nanoparticles: from single component to mixed components?
  Tao Wang,Yangyang Liu,Yue Deng,Hongbo Fu,Jianmin Chen Environ. Sci.: Nano, 2018,5, 1821-1833
• 2. Excimer and exciplex formation in a pair of bright phosphorescent isomers constructed from Cu3(pyrazolate)3 and Cu3I3 coordination luminophores?
  Shun-Ze Zhan,Mian Li,Xiao-Ping Zhou,Dan Li,Seik Weng Ng RSC Adv., 2011,1, 1457-1459
• 3. Evolution of cellulose into flexible conductive green electronics: a smart strategy to fabricate sustainable electrodes for supercapacitors
  Tengfei Yu,Yuehan Wu,Wei Li,Bin Li RSC Adv., 2014,4, 34134-34143
• 4. Enabling high-throughput single-animal gene-expression studies with molecular and micro-scale technologies
  Jason Wan Lab Chip, 2020,20, 4528-4538
• 5. Evolution in surface coverage of CH3NH3PbI3?XClXvia heat assisted solvent vapour treatment and their effects on photovoltaic performance of devices
  Dhirendra K. Chaudhary,Pramendra Kumar,Lokendra Kumar RSC Adv., 2016,6, 94731-94738

3-(Diethylsulfamoyl)-4-methylbenzoic Acid (CAS No. 313259-91-5): A Comprehensive Overview

3-(Diethylsulfamoyl)-4-methylbenzoic acid (CAS No. 313259-91-5) is a compound of significant interest in the fields of organic chemistry, pharmacology, and materials science. This compound, characterized by its unique structure and functional groups, has garnered attention due to its potential applications in drug development and advanced materials. The molecule consists of a benzoic acid backbone with a diethylsulfamoyl group attached at the meta position and a methyl group at the para position, making it a versatile platform for further chemical modifications.

The diethylsulfamoyl group in this compound plays a crucial role in its chemical reactivity and biological activity. Sulfonamide groups are well-known for their ability to modulate the physicochemical properties of molecules, such as solubility, stability, and bioavailability. Recent studies have highlighted the importance of sulfonamides in drug design, particularly in the development of kinase inhibitors and anti-inflammatory agents. The methyl group at the para position further enhances the compound's stability and may influence its interaction with biological targets.

Recent advancements in synthetic chemistry have enabled the efficient synthesis of 3-(diethylsulfamoyl)-4-methylbenzoic acid through various routes. One notable approach involves the coupling of diethylthiourea with a substituted benzoic acid derivative under mild conditions. This method not only ensures high yields but also allows for precise control over the substitution pattern on the aromatic ring. The compound's synthesis has been optimized to minimize environmental impact, aligning with current green chemistry principles.

In terms of applications, 3-(diethylsulfamoyl)-4-methylbenzoic acid has shown promise in several areas. In pharmacology, it has been investigated as a lead compound for developing novel therapeutic agents targeting various diseases, including cancer and inflammatory disorders. Its ability to inhibit key enzymes involved in disease progression makes it a valuable candidate for further preclinical studies. Additionally, this compound has potential applications in materials science, particularly in the development of advanced polymers and coatings due to its unique structural properties.

Recent research has also explored the biodegradation pathways of 3-(diethylsulfamoyl)-4-methylbenzoic acid, providing insights into its environmental fate. Studies indicate that under aerobic conditions, the compound undergoes microbial degradation via hydrolysis and oxidation mechanisms, leading to the formation of less complex intermediates. These findings are critical for assessing the environmental impact of this compound and ensuring its safe use in industrial and pharmaceutical applications.

The molecular structure of 3-(diethylsulfamoyl)-4-methylbenzoic acid is highly amenable to further functionalization, enabling chemists to tailor its properties for specific applications. For instance, substitution at different positions on the aromatic ring can modulate its electronic properties, solubility, and reactivity. Such modifications have been exploited in recent studies to develop derivatives with enhanced biological activity or improved material properties.

In conclusion, 3-(diethylsulfamoyl)-4-methylbenzoic acid (CAS No. 313259-91-5) is a multifaceted compound with significant potential across various scientific domains. Its unique structure, coupled with recent advancements in synthesis and application studies, positions it as a key player in future research and development efforts.

• 1576-46-1(3-Diethylsulfamoylbenzoic acid)
• 1213-06-5(Etebenecid)
• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
• 89640-58-4(2-Iodo-4-nitrophenylhydrazine)