• 1. An investigation into the origin of variations in photovoltaic performance using D–D–π–A and D–A–π–A triphenylimidazole dyes with a copper electrolyte?
  Govind Reddy Mol. Syst. Des. Eng., 2021,6, 779-789
• 2. Aggregation behaviour of biocompatible choline carboxylate ionic liquids and their interactions with biomolecules through experimental and theoretical investigations?
  Somenath Panda,Kaushik Kundu,Anusha Basaiahgari,Sanjib Senapati,Ramesh L. Gardas New J. Chem., 2018,42, 7105-7118
• 3. An approach to C–N activation: coupling of arenesulfonyl hydrazides and arenesulfonyl chlorides with tert-amines via a metal-, oxidant- and halogen-free anodic oxidation??
  M. Sheykhan,S. Khani,S. Shaabanzadeh,M. Joafshan Green Chem., 2017,19, 5940-5948
• 4. An autonomous self-optimizing flow machine for the synthesis of pyridine–oxazoline (PyOX) ligands?
  Eric Wimmer,Daniel Cortés-Borda,Solène Brochard,Elvina Barré,Charlotte Truchet,Fran?ois-Xavier Felpin React. Chem. Eng., 2019,4, 1608-1615
• 5. An arsenic trioxide nanoparticle prodrug (ATONP) potentiates a therapeutic effect on an aggressive hepatocellular carcinoma model via enhancement of intratumoral arsenic accumulation and disturbance of the tumor microenvironment?
  Xin Fu,Qing-rong Liang,Rong-guang Luo,Yan-shu Li,Xiao-ping Xiao,Lu-lu Yu,Wen-zhe Shan,Guang-qin Fan J. Mater. Chem. B, 2019,7, 3088-3099

Benzenesulfonamide,4-hydroxy-N-methyl- (CAS No. 3077-61-0): A Comprehensive Overview of Its Chemical Properties and Emerging Applications

Benzenesulfonamide,4-hydroxy-N-methyl- (CAS No. 3077-61-0) is a sulfonamide derivative that has garnered significant attention in the field of chemical biology and pharmaceutical research due to its unique structural properties and potential therapeutic applications. This compound, characterized by a benzene ring substituted with a sulfonamide group and a hydroxyl group at the 4-position, along with a methyl group at the N-position, exhibits distinct chemical and biological characteristics that make it a valuable candidate for further investigation.

The chemical structure of Benzenesulfonamide,4-hydroxy-N-methyl- (CAS No. 3077-61-0) consists of a benzene core linked to a sulfonamide moiety (-SO?NH?), with modifications at the 4-position and the nitrogen atom. The presence of the hydroxyl group at the 4-position introduces polarity and potential hydrogen bonding capabilities, while the methyl group at the nitrogen enhances the compound's solubility and reactivity. These structural features contribute to its versatility in various chemical and biological interactions.

In recent years, Benzenesulfonamide,4-hydroxy-N-methyl- (CAS No. 3077-61-0) has been studied for its potential role in drug development. Sulfonamide derivatives are well-known for their antimicrobial and anti-inflammatory properties, and this compound is no exception. The sulfonamide group is particularly effective in disrupting bacterial cell wall synthesis, making it a promising candidate for antibiotics. Additionally, the hydroxyl and methyl groups may enhance binding affinity to biological targets, improving drug efficacy.

One of the most compelling aspects of Benzenesulfonamide,4-hydroxy-N-methyl- (CAS No. 3077-61-0) is its potential application in targeted therapy. Researchers have been exploring its use in developing drugs that specifically target cancer cells without harming healthy tissues. The compound's ability to interact with enzymes and receptors overexpressed in certain cancer types makes it an attractive candidate for personalized medicine approaches. Preliminary studies have shown promising results in inhibiting tumor growth in vitro, suggesting its potential as an anticancer agent.

The synthesis of Benzenesulfonamide,4-hydroxy-N-methyl- (CAS No. 3077-61-0) involves multi-step organic reactions that require precise control over reaction conditions to ensure high yield and purity. The process typically begins with the functionalization of a benzene ring to introduce the sulfonamide group, followed by modifications at the 4-position and nitrogen atom. Advanced synthetic techniques such as catalytic hydrogenation and nucleophilic substitution reactions are often employed to achieve the desired structure efficiently.

The physicochemical properties of Benzenesulfonamide,4-hydroxy-N-methyl- (CAS No. 3077-61-0) are also of great interest. Its solubility in both polar and non-polar solvents makes it suitable for various formulation strategies in drug delivery systems. Additionally, its stability under different storage conditions ensures that it can be effectively used in pharmaceutical applications without degradation over time.

In conclusion, Benzenesulfonamide,4-hydroxy-N-methyl- (CAS No. 3077-61-0) is a multifaceted compound with significant potential in pharmaceutical research and development. Its unique structural features make it an effective candidate for antimicrobial agents, anti-inflammatory drugs, and targeted cancer therapies. Further research is needed to fully elucidate its mechanisms of action and optimize its therapeutic applications.

• 7010-86-8(4-Methoxy-N-methylbenzenesulfonamide)
• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
• 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
• 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)