Cas no 305377-31-5 (1-(Trifluoromethyl)cyclopropane-1,2-dicarboxylic Acid)
1-(Trifluoromethyl)cyclopropane-1,2-dicarboxylic acid is a fluorinated cyclopropane derivative featuring both carboxylic acid and trifluoromethyl functional groups. Its rigid cyclopropane ring and electron-withdrawing trifluoromethyl group contribute to its utility as a versatile building block in organic synthesis and medicinal chemistry. The dicarboxylic acid moiety allows for further functionalization, making it valuable for the development of pharmaceuticals, agrochemicals, and specialty materials. The trifluoromethyl group enhances metabolic stability and lipophilicity, which is advantageous in drug design. This compound is particularly useful in the synthesis of bioactive molecules, where its unique structural properties can influence binding affinity and selectivity.
305377-31-5 structure
Product Name:1-(Trifluoromethyl)cyclopropane-1,2-dicarboxylic Acid
CAS No:305377-31-5
MF:C6H5F3O4
MW:198.096712827682
MDL:MFCD00546281
CID:867780
PubChem ID:2829680
Update Time:2025-06-10
1-(Trifluoromethyl)cyclopropane-1,2-dicarboxylic Acid Chemical and Physical Properties
Names and Identifiers
-
- 1-(trifluoromethyl)cyclopropane-1,2-dicarboxylic Acid
- C6H5F3O4
- HMS1610B16
- STL335058
- 1-(Trifluoromethyl)cyclopropane-1,2-dicarboxylic Acid
-
- MDL： MFCD00546281
- Inchi： 1S/C6H5F3O4/c7-6(8,9)5(4(12)13)1-2(5)3(10)11/h2H,1H2,(H,10,11)(H,12,13)
- InChI Key： PKHUWUZQELPYRZ-UHFFFAOYSA-N
- SMILES： FC(C1(C(=O)O)CC1C(=O)O)(F)F
Computed Properties
- Hydrogen Bond Donor Count: 2
- Hydrogen Bond Acceptor Count: 7
- Heavy Atom Count: 13
- Rotatable Bond Count: 2
- Complexity: 272
- XLogP3: 0.4
- Topological Polar Surface Area: 74.6
1-(Trifluoromethyl)cyclopropane-1,2-dicarboxylic Acid Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Enamine | EN300-295801-1g |
1-(trifluoromethyl)cyclopropane-1,2-dicarboxylic acid |
305377-31-5 | 1g |
$2152.0 | 2023-09-06 | ||
| Enamine | EN300-295801-5g |
1-(trifluoromethyl)cyclopropane-1,2-dicarboxylic acid |
305377-31-5 | 5g |
$6239.0 | 2023-09-06 | ||
| Enamine | EN300-295801-10g |
1-(trifluoromethyl)cyclopropane-1,2-dicarboxylic acid |
305377-31-5 | 10g |
$9252.0 | 2023-09-06 | ||
| SHANG HAI BI DE YI YAO KE JI GU FEN Co., Ltd. | BD01064620-1g |
1-(Trifluoromethyl)cyclopropane-1,2-dicarboxylic acid |
305377-31-5 | 95% | 1g |
￥10780.0 | 2023-02-28 | |
| SHANG HAI HAO HONG Biomedical Technology Co., Ltd. | 1521459-25mg |
1-(Trifluoromethyl)cyclopropane-1,2-dicarboxylic acid |
305377-31-5 | 98% | 25mg |
￥28695.00 | 2024-08-02 | |
| Enamine | EN300-295801-0.05g |
1-(trifluoromethyl)cyclopropane-1,2-dicarboxylic acid |
305377-31-5 | 0.05g |
$1807.0 | 2023-09-06 | ||
| Enamine | EN300-295801-0.1g |
1-(trifluoromethyl)cyclopropane-1,2-dicarboxylic acid |
305377-31-5 | 0.1g |
$1893.0 | 2023-09-06 | ||
| Enamine | EN300-295801-0.25g |
1-(trifluoromethyl)cyclopropane-1,2-dicarboxylic acid |
305377-31-5 | 0.25g |
$1980.0 | 2023-09-06 | ||
| Enamine | EN300-295801-0.5g |
1-(trifluoromethyl)cyclopropane-1,2-dicarboxylic acid |
305377-31-5 | 0.5g |
$2066.0 | 2023-09-06 | ||
| Enamine | EN300-295801-1.0g |
1-(trifluoromethyl)cyclopropane-1,2-dicarboxylic acid |
305377-31-5 | 1g |
$0.0 | 2023-06-07 |
1-(Trifluoromethyl)cyclopropane-1,2-dicarboxylic Acid Related Literature
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1. An all-solid-state imprinted polymer-based potentiometric sensor for determination of bisphenol S?Rongning Liang,Tanji Yin,Ruiqing Yao,Wei Qin RSC Adv., 2016,6, 73308-73312
-
Inês S. Albuquerque,Hélia F. Jeremias,Miguel Chaves-Ferreira,Dijana Matak-Vinkovic,Omar Boutureira,Carlos C. Rom?o Chem. Commun., 2015,51, 3993-3996
-
Muniyandi Sankaralingam,So Hyun Jeon,Yong-Min Lee,Mi Sook Seo,Wonwoo Nam Dalton Trans., 2016,45, 376-383
-
Dhamodaran Manikandan,S. Amirthapandian,I. S. Zhidkov,A. I. Kukharenko,S. O. Cholakh,Ramaswamy Murugan Phys. Chem. Chem. Phys., 2018,20, 6500-6514
Related Categories
- Solvents and Organic Chemicals Organic Compounds Organic acids and derivatives Carboxylic acids and derivatives Cyclopropanecarboxylic acids
- Solvents and Organic Chemicals Organic Compounds Organic acids and derivatives Carboxylic acids and derivatives Cyclopropanecarboxylic acids and derivatives Cyclopropanecarboxylic acids
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