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• Solvents and Organic Chemicals Organic Compounds Organic oxygen compounds Organooxygen compounds Secondary alcohols
• Solvents and Organic Chemicals Organic Compounds Organic oxygen compounds Organooxygen compounds Alcohols and polyols Secondary alcohols

4-Chlorocyclohexanol (CAS No. 30485-71-3): Properties, Applications, and Industry Insights

4-Chlorocyclohexanol (CAS No. 30485-71-3) is a versatile chlorinated cycloaliphatic alcohol with significant applications in organic synthesis and specialty chemicals. This compound, also known as para-chlorocyclohexanol, features a cyclohexane ring substituted with both a hydroxyl group and a chlorine atom at the 4-position, giving it unique reactivity patterns that make it valuable for various industrial processes.

The molecular structure of 4-Chlorocyclohexanol (C6H11ClO) exhibits interesting stereochemical properties due to the cyclohexane ring's chair conformation. Researchers have studied its cis- and trans-isomers extensively, as these configurations influence the compound's physical properties and chemical behavior. The presence of both polar (hydroxyl) and moderately polar (chloro) groups makes this compound soluble in many organic solvents while maintaining limited water solubility.

In pharmaceutical applications, 4-Chlorocyclohexanol derivatives serve as important intermediates for drug development. Recent studies highlight its potential in creating novel antimicrobial agents, addressing growing concerns about antibiotic resistance—a hot topic in medical research. The compound's structural flexibility allows medicinal chemists to develop targeted molecules with improved efficacy against resistant bacterial strains.

The chemical industry values 4-Chlorocyclohexanol 30485-71-3 for its role in producing specialty polymers and fine chemicals. Its reactive sites enable various transformations, including oxidation to corresponding ketones or further functionalization through nucleophilic substitution reactions. Manufacturers particularly appreciate its stability under standard storage conditions, making it a reliable building block for complex syntheses.

Environmental considerations have brought attention to chlorocyclohexanol compounds in green chemistry applications. Researchers are exploring its use in catalytic processes that minimize waste generation, aligning with the industry's shift toward sustainable practices. The compound's moderate reactivity profile makes it suitable for atom-economical reactions that reduce environmental impact.

Analytical chemists frequently employ advanced techniques like GC-MS and HPLC to characterize 4-Chlorocyclohexanol purity and identify potential impurities. Quality control protocols have become increasingly stringent, especially for pharmaceutical-grade material, reflecting the industry's focus on product safety and consistency.

Market trends indicate growing demand for high-purity 4-Chlorocyclohexanol, particularly in regions with active pharmaceutical and agrochemical industries. Suppliers are responding by developing improved purification methods and more efficient synthetic routes. The compound's global availability remains stable, though regional supply chain factors occasionally affect delivery timelines.

Recent innovations in 4-Chlorocyclohexanol synthesis focus on reducing energy consumption and improving yield. Catalytic methods using novel metal complexes show promise for more sustainable production. These developments address two key industry challenges: cost efficiency and environmental responsibility.

Safety data for CAS 30485-71-3 indicates standard handling precautions typical for halogenated alcohols. Proper personal protective equipment (PPE) including gloves and eye protection is recommended when working with this compound. Storage in cool, dry conditions away from strong oxidizers helps maintain product stability over extended periods.

Academic interest in 4-Chlorocyclohexanol research continues to grow, with recent publications exploring its use in asymmetric synthesis and chiral auxiliary development. These applications leverage the compound's stereochemical properties to create enantiomerically pure products—a crucial requirement in modern pharmaceutical manufacturing.

Future applications may expand into materials science, where researchers are investigating chlorocyclohexanol-based monomers for specialty polymers with unique thermal and mechanical properties. The compound's structural features offer possibilities for developing new materials with tailored characteristics for specific industrial needs.

For laboratory use, 4-Chlorocyclohexanol suppliers typically offer various packaging options ranging from small research quantities to bulk industrial volumes. Customers increasingly request detailed certificates of analysis and safety documentation, reflecting heightened quality awareness across the chemical industry.

Technical support for 4-Chlorocyclohexanol applications has become more comprehensive, with manufacturers providing detailed handling guidelines and application notes. This trend responds to customer needs for better technical resources when working with specialized intermediates in complex syntheses.

Regulatory compliance remains straightforward for 30485-71-3, as the compound falls outside most restricted substance lists. However, prudent manufacturers maintain up-to-date regulatory monitoring to ensure continued compliance with evolving chemical regulations worldwide.

In analytical applications, 4-Chlorocyclohexanol standard serves as a reference material for method development and quality control. Its well-characterized properties make it suitable for calibrating instruments and validating analytical procedures in pharmaceutical and environmental testing laboratories.

The compound's future looks promising as researchers discover new applications in green chemistry and sustainable synthesis. Its balanced reactivity profile and structural features position it well for emerging technologies that prioritize efficiency and environmental compatibility in chemical manufacturing.

• 146615-55-6(1-Chlorocyclohexan-1-ol)
• 113569-09-8(2,6-dichloroheptan-4-ol)
• 33889-19-9
• 51776-94-4(2-chlorocyclodecanol)
• 16536-58-6(2-Chlorocyclohexanol, cis)
• 61505-43-9(2-PENTANOL, 4-CHLORO-, (R*,S*)-)
• 58705-87-6(2-Octanol, 5-chloro-)
• 29538-77-0(Cyclohexanol,4-chloro-, trans-)
• 1561-86-0(2-Chlorocyclohexanol)
• 6628-80-4(Cyclohexanol,2-chloro-, (1R,2R)-rel-)