Cas no 30273-11-1 (4-(butan-2-yl)aniline)

4-(Butan-2-yl)aniline is a substituted aniline derivative featuring a sec-butyl group at the para position of the aromatic ring. This compound is commonly utilized as an intermediate in organic synthesis, particularly in the production of pharmaceuticals, agrochemicals, and specialty chemicals. Its structure allows for further functionalization, making it valuable in the development of complex molecules. The sec-butyl substituent enhances steric and electronic properties, influencing reactivity in coupling and condensation reactions. The compound is typically supplied as a high-purity liquid or solid, ensuring consistent performance in synthetic applications. Proper handling under inert conditions is recommended due to its sensitivity to oxidation and potential amine-related hazards.
4-(butan-2-yl)aniline structure
4-(butan-2-yl)aniline structure
Product Name:4-(butan-2-yl)aniline
CAS No:30273-11-1
MF:C10H15N
MW:149.232802629471
MDL:MFCD00010223
CID:88868
PubChem ID:121771
Update Time:2025-05-24

4-(butan-2-yl)aniline Chemical and Physical Properties

Names and Identifiers

    • 4-(sec-Butyl)aniline
    • Butylaniline
    • 4-sec-Butylaniline
    • (4-sec-Butylphenyl)amine
    • 4-butan-2-ylaniline
    • 4-sec-butylbenzenamine
    • p-sec-Butylaniline
    • 4-(1-methylpropyl)aniline
    • 4-(2-Butyl)aniline
    • 4-s-butyl-aniline
    • 4-sec-butyl-aniline
    • EINECS 250-108-9
    • 4-(1-methylpropyl)-benzenamin
    • 4-(butan-2-yl)aniline
    • 4-sec-butyl-phenylamine
    • AC-11848
    • AKOS000120309
    • BP-10283
    • 30273-11-1
    • SB47733
    • B1256
    • NS00051015
    • A876250
    • AM9881
    • FT-0619463
    • MFCD00010223
    • Benzenamine, 4-(1-methylpropyl)-
    • GS-3260
    • 4-sec-butyl aniline
    • N-(4-sec-butyl-phenyl)-amine
    • CS-W022027
    • AKOS016039392
    • SY051829
    • 4-Amino-sec-butylbenzene
    • 4-sec-butylphenylamine
    • SCHEMBL112316
    • EN300-20622
    • Aniline, p-sec-butyl-
    • DTXSID00865535
    • (R)-4-(sec-Butyl)aniline
    • DA-07133
    • 181288-08-4
    • STL481760
    • MDL: MFCD00010223
    • Inchi: 1S/C10H15N/c1-3-8(2)9-4-6-10(11)7-5-9/h4-8H,3,11H2,1-2H3
    • InChI Key: NVVVQTNTLIAISI-UHFFFAOYSA-N
    • SMILES: NC1C=CC(=CC=1)C(C)CC

Computed Properties

  • Exact Mass: 149.12000
  • Monoisotopic Mass: 149.12
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 1
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 2
  • Complexity: 103
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 1
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: nothing
  • XLogP3: nothing
  • Topological Polar Surface Area: 26A^2

Experimental Properties

  • Color/Form: Not determined
  • Density: 0.977?g/mL?at 25?°C(lit.)
  • Melting Point: 1.08°C (estimate)
  • Boiling Point: 238°C(lit.)
  • Flash Point: 226?°F
  • Refractive Index: n20/D 1.537(lit.)
  • PSA: 26.02000
  • LogP: 3.36350
  • Solubility: Soluble in ether \ benzene

4-(butan-2-yl)aniline Security Information

4-(butan-2-yl)aniline Customs Data

  • HS CODE:2921420090
  • Customs Data:

    China Customs Code:

    2921420090

    Overview:

    2921420090 Other aniline derivatives and their salts. VAT:17.0% Tax refund rate:9.0% Regulatory conditions:nothing MFN tariff:6.5% general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    HS:2921420090 aniline derivatives and their salts VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

4-(butan-2-yl)aniline Pricemore >>

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Additional information on 4-(butan-2-yl)aniline

4-(Butan-2-Yl)Aniline: A Comprehensive Overview

The compound with CAS No 30273-11-1, commonly referred to as 4-(butan-2-yl)aniline, is a significant organic chemical that has garnered attention in various fields due to its unique properties and versatile applications. This article delves into the structural characteristics, synthesis methods, and recent advancements in the utilization of this compound, providing a comprehensive understanding of its role in contemporary chemistry and industry.

4-(Butan-2-Yl)Aniline is an aromatic amine derivative characterized by its benzene ring substituted with an amino group (-NH?) and a butan-2-yl group at the para position. The molecular formula of this compound is C??H??N, and it exhibits a melting point of approximately 56°C. Its structure endows it with unique electronic properties, making it suitable for various chemical reactions and applications.

Recent studies have highlighted the importance of 4-(butan-2-Yl)Aniline in the synthesis of advanced materials. For instance, researchers have explored its role as a precursor in the development of novel polymeric materials with enhanced thermal stability and mechanical properties. These findings underscore its potential in advancing material science and engineering.

The synthesis of 4-(butan-2-Yl)Aniline typically involves nucleophilic aromatic substitution or coupling reactions. One prominent method entails the reaction of aniline with 2-bromobutane under specific conditions to achieve the desired substitution at the para position. This approach has been optimized in recent years to enhance yield and purity, making it more feasible for large-scale production.

In terms of applications, 4-(butan-2-Yl)Aniline finds extensive use in pharmaceuticals, agrochemicals, and specialty chemicals. Its role as an intermediate in drug synthesis has been particularly noteworthy, with recent studies demonstrating its potential in developing bioactive compounds targeting specific diseases. Additionally, its incorporation into agrochemical formulations has shown promise in improving crop protection efficacy.

The environmental impact of 4-(butan-2-Yl)Aniline has also come under scrutiny in recent research. Studies indicate that while it exhibits moderate biodegradability, its persistence in certain environmental conditions necessitates careful handling and disposal practices to mitigate ecological risks.

In conclusion, CAS No 30273-11-1 (4-(butan-2-Yl)Aniline) stands as a pivotal compound in modern chemistry, offering diverse applications across multiple industries. With ongoing research unraveling new potentials and refining existing methodologies, this compound continues to play a vital role in driving innovation and progress in the chemical sciences.

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