Cas no 30189-36-7 (Boc-Lys(Boc)-OSu)
Boc-Lys(Boc)-OSu Chemical and Physical Properties
Names and Identifiers
-
- (S)-2,5-Dioxopyrrolidin-1-yl 2,6-bis((tert-butoxycarbonyl)amino)hexanoate
- Boc-Lys(Boc)-OSu
- (2,5-dioxopyrrolidin-1-yl) (2S)-2,6-bis[(2-methylpropan-2-yl)oxycarbonylamino]hexanoate
- H-Glu(OEt)-OEt·HCl
- N,N'-Di-Boc-L-lysine hydroxysuccinimide ester
- Nα,ε-Bis-Boc-L-lysine N-hydroxysuccinimide ester
- A,N
- A-Di-Boc-L-lysine hydroxysuccinimide ester
- Boc-L-Lys(Boc)-OSu
- diboc-lysin-N-hydroxysuccinimid ester
- Nalpha,Nepsilon-Di-Boc-L-lysine hydroxysuccinimide ester
- N-α,e-di-Boc-L-lysine N-hydroxysucciMide ester
- N,N -Di-Boc-L-lysine hydroxysuccinimide ester
- PubChem14936
- N
- IQVLXQGNLCPZCL-ZDUSSCGKSA-N
- C20H33N3O8
- U798
- AB1006885
- AX8009107
- ST24035783
- ST51014923
-
- MDL： MFCD00057898
- Inchi： 1S/C20H33N3O8/c1-19(2,3)29-17(27)21-12-8-7-9-13(22-18(28)30-20(4,5)6)16(26)31-23-14(24)10-11-15(23)25/h13H,7-12H2,1-6H3,(H,21,27)(H,22,28)/t13-/m0/s1
- InChI Key： IQVLXQGNLCPZCL-ZDUSSCGKSA-N
- SMILES： O(C([C@H](CCCCNC(=O)OC(C)(C)C)NC(=O)OC(C)(C)C)=O)N1C(CCC1=O)=O
- BRN： 1559007
Computed Properties
- Exact Mass: 443.22700
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 2
- Hydrogen Bond Acceptor Count: 8
- Heavy Atom Count: 31
- Rotatable Bond Count: 13
- Complexity: 678
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 1
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Surface Charge: 0
- Tautomer Count: 12
- XLogP3: 1.8
- Topological Polar Surface Area: 140
Experimental Properties
- Color/Form: Not determined
- Density: 1.21
- Melting Point: 74-85°C
- Refractive Index: 1.513
- Water Partition Coefficient: Slightly soluble in water.
- PSA: 140.34000
- LogP: 2.90160
- Sensitiveness: Moisture Sensitive
- Specific Rotation: -27° to -23° (c=1, DMF)
- Optical Activity: [α]20/D ?25.5±1.5°, c =?1% in DMF
- Solubility: Not determined
Boc-Lys(Boc)-OSu Security Information
- Signal Word：Warning
- Hazard Statement： H315-H319-H335
- Warning Statement： P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501
- Hazardous Material transportation number：NONH for all modes of transport
- WGK Germany：3
- FLUKA BRAND F CODES：10-21
- Storage Condition：?20°C
Boc-Lys(Boc)-OSu Customs Data
- HS CODE：2925190090
- Customs Data：
China Customs Code:
2925190090Overview:
2925190090 Other imides and their derivative salts. VAT:17.0% Tax refund rate:9.0% Regulatory conditions:nothing MFN tariff:6.5% general tariff:30.0%
Declaration elements:
Product Name, component content, use to
Summary:
2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
Boc-Lys(Boc)-OSu Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| TRC | B657060-1g |
Boc-Lys(Boc)-OSu |
30189-36-7 | 1g |
$ 52.00 | 2023-09-08 | ||
| TRC | B657060-5g |
Boc-Lys(Boc)-OSu |
30189-36-7 | 5g |
$ 69.00 | 2023-09-08 | ||
| TRC | B657060-25g |
Boc-Lys(Boc)-OSu |
30189-36-7 | 25g |
$ 184.00 | 2023-09-08 | ||
| TRC | B657060-100g |
Boc-Lys(Boc)-OSu |
30189-36-7 | 100g |
$ 552.00 | 2023-04-18 | ||
| SHANG HAI YI EN HUA XUE JI SHU Co., Ltd. | R026017-100g |
Boc-Lys(Boc)-OSu |
30189-36-7 | 97% | 100g |
￥21056 | 2023-09-09 | |
| SHANG HAI YI EN HUA XUE JI SHU Co., Ltd. | R026017-25g |
Boc-Lys(Boc)-OSu |
30189-36-7 | 97% | 25g |
￥857 | 2023-09-09 | |
| SHANG HAI YI EN HUA XUE JI SHU Co., Ltd. | R026017-5g |
Boc-Lys(Boc)-OSu |
30189-36-7 | 97% | 5g |
￥307 | 2023-09-09 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | B116707-25g |
Boc-Lys(Boc)-OSu |
30189-36-7 | 97% | 25g |
￥713.90 | 2023-09-04 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | B116707-5g |
Boc-Lys(Boc)-OSu |
30189-36-7 | 97% | 5g |
￥255.90 | 2023-09-04 | |
| Chemenu | CM197717-25g |
(S)-2,5-Dioxopyrrolidin-1-yl2,6-bis((tert-butoxycarbonyl)amino)hexanoate |
30189-36-7 | 95% | 25g |
$112 | 2021-06-09 |
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Boc-Lys(Boc)-OSu Related Literature
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Additional information on Boc-Lys(Boc)-OSu
Boc-Lys(Boc)-OSu (CAS No. 30189-36-7): A Comprehensive Guide to Its Properties and Applications
Boc-Lys(Boc)-OSu (CAS No. 30189-36-7) is a highly versatile N-hydroxysuccinimide (NHS) ester derivative widely used in peptide synthesis and bioconjugation. This compound, also known as N-α-Boc-N-ε-Boc-L-lysine N-hydroxysuccinimide ester, plays a crucial role in modern biochemical research and pharmaceutical development. Its unique structure, featuring dual Boc (tert-butoxycarbonyl) protecting groups, makes it particularly valuable for controlled amino acid coupling reactions.
The molecular formula of Boc-Lys(Boc)-OSu is C20H33N3O7, with a molecular weight of 427.49 g/mol. This white to off-white crystalline powder is soluble in organic solvents like dimethylformamide (DMF) and dichloromethane (DCM), but has limited solubility in water. Researchers often search for "Boc-Lys(Boc)-OSu solubility" or "Boc-Lys(Boc)-OSu storage conditions" as these properties are critical for experimental success.
In peptide synthesis, Boc-Lys(Boc)-OSu serves as a key building block for introducing lysine residues with protected side chains. The compound's popularity stems from its ability to provide selective amine protection during solid-phase peptide synthesis (SPPS). Many researchers investigating "how to use Boc-Lys(Boc)-OSu in peptide synthesis" find this reagent invaluable for creating complex peptide structures with precise control over reactivity.
The NHS ester moiety in Boc-Lys(Boc)-OSu enables efficient coupling with primary amines under mild conditions, making it ideal for bioconjugation applications. This property has led to its widespread use in creating peptide-protein conjugates, peptide-drug conjugates, and various biomaterials. Recent trends show increased interest in "Boc-Lys(Boc)-OSu for antibody-drug conjugates" as the pharmaceutical industry explores more targeted therapies.
Quality control of Boc-Lys(Boc)-OSu typically involves HPLC analysis and melting point determination (reported between 90-95°C). Researchers frequently search for "Boc-Lys(Boc)-OSu purity standards" and "Boc-Lys(Boc)-OSu analytical methods" to ensure reagent quality. The compound should be stored at 2-8°C in a dry environment to maintain stability, as moisture can lead to hydrolysis of the active ester group.
The global market for Boc-Lys(Boc)-OSu has grown significantly due to increasing demand in peptide therapeutics development. With the rise of "personalized medicine" and "targeted drug delivery" approaches, this compound has become more relevant than ever. Manufacturers have responded by improving synthesis protocols and scaling up production to meet research and industrial needs.
When working with Boc-Lys(Boc)-OSu, proper handling procedures should be followed, including the use of appropriate personal protective equipment. While not classified as hazardous under normal conditions, standard laboratory precautions apply. Researchers often look for "Boc-Lys(Boc)-OSu safety data" and "Boc-Lys(Boc)-OSu handling guidelines" before beginning experiments.
Recent advancements in peptide chemistry have highlighted new applications for Boc-Lys(Boc)-OSu, particularly in the development of peptide-based vaccines and diagnostic reagents. The compound's ability to introduce protected lysine residues makes it valuable for creating immunogenic epitopes and stable peptide tags. These emerging applications have generated increased interest in "Boc-Lys(Boc)-OSu for vaccine development" among researchers.
The synthesis of Boc-Lys(Boc)-OSu typically involves the reaction of Boc-Lys(Boc)-OH with N-hydroxysuccinimide in the presence of a coupling agent like dicyclohexylcarbodiimide (DCC). Process optimization has been a focus area for manufacturers aiming to improve yield and purity. Search queries such as "Boc-Lys(Boc)-OSu synthesis protocol" reflect the ongoing interest in production methodologies.
In analytical applications, Boc-Lys(Boc)-OSu serves as a valuable standard and reagent for mass spectrometry studies and chromatographic analysis of modified peptides. Its well-characterized properties make it ideal for method development and calibration in proteomics research. The growing field of "peptidomics" has further increased demand for high-quality Boc-Lys(Boc)-OSu reference materials.
The future of Boc-Lys(Boc)-OSu looks promising as peptide-based therapies continue to gain traction in medicine. With increasing research into "peptide drugs for metabolic disorders" and "antimicrobial peptides", the demand for specialized amino acid derivatives like Boc-Lys(Boc)-OSu is expected to grow. Ongoing developments in green chemistry approaches may also lead to more sustainable production methods for this important biochemical reagent.
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