Cas no 301823-61-0 (Methyl 4-chloro-6-fluoroquinoline-2-carboxylate)
Methyl 4-chloro-6-fluoroquinoline-2-carboxylate Chemical and Physical Properties
Names and Identifiers
-
- Methyl 4-chloro-6-fluoroquinoline-2-carboxylate
- ACMC-209hdo
- AG-E-98925
- AK-94469
- ANW-26794
- CTK4G4620
- KB-54338
- SureCN3281931
- 301823-61-0
- METHYL4-CHLORO-6-FLUOROQUINOLINE-2-CARBOXYLATE
- SCHEMBL3281931
- DTXSID40674840
- AKOS012682800
- SB70298
- MFCD11855884
- CS-0084834
- BS-27785
- D74575
-
- MDL: MFCD11855884
- Inchi: 1S/C11H7ClFNO2/c1-16-11(15)10-5-8(12)7-4-6(13)2-3-9(7)14-10/h2-5H,1H3
- InChI Key: CXAWNDWONHOZNO-UHFFFAOYSA-N
- SMILES: ClC1C=C(C(=O)OC)N=C2C=CC(=CC2=1)F
Computed Properties
- Exact Mass: 239.01501
- Monoisotopic Mass: 239.015
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 3
- Heavy Atom Count: 16
- Rotatable Bond Count: 2
- Complexity: 277
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 39.2A^2
- XLogP3: 3.1
Experimental Properties
- Density: 1.403
- Boiling Point: 348.738 °C at 760 mmHg
- Flash Point: 164.711 °C
- PSA: 39.19
Methyl 4-chloro-6-fluoroquinoline-2-carboxylate Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Alichem | A189007329-5g |
Methyl 4-chloro-6-fluoroquinoline-2-carboxylate |
301823-61-0 | 95% | 5g |
$829.92 | 2023-09-02 | |
| Fluorochem | 216042-1g |
Methyl 4-chloro-6-fluoroquinoline-2-carboxylate |
301823-61-0 | 95% | 1g |
£300.00 | 2022-03-01 | |
| Fluorochem | 216042-5g |
Methyl 4-chloro-6-fluoroquinoline-2-carboxylate |
301823-61-0 | 95% | 5g |
£1050.00 | 2022-03-01 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | M183532-5g |
Methyl 4-chloro-6-fluoroquinoline-2-carboxylate |
301823-61-0 | 98% | 5g |
¥8220.90 | 2023-09-01 | |
| Chemenu | CM144656-5g |
Methyl 4-chloro-6-fluoroquinoline-2-carboxylate |
301823-61-0 | 95% | 5g |
$746 | 2021-08-05 | |
| TRC | M295733-100mg |
Methyl 4-chloro-6-fluoroquinoline-2-carboxylate |
301823-61-0 | 100mg |
$138.00 | 2023-05-18 | ||
| TRC | M295733-250mg |
Methyl 4-chloro-6-fluoroquinoline-2-carboxylate |
301823-61-0 | 250mg |
$270.00 | 2023-05-18 | ||
| TRC | M295733-500mg |
Methyl 4-chloro-6-fluoroquinoline-2-carboxylate |
301823-61-0 | 500mg |
$408.00 | 2023-05-18 | ||
| TRC | M295733-1g |
Methyl 4-chloro-6-fluoroquinoline-2-carboxylate |
301823-61-0 | 1g |
$574.00 | 2023-05-18 | ||
| Chemenu | CM144656-250mg |
Methyl 4-chloro-6-fluoroquinoline-2-carboxylate |
301823-61-0 | 95% | 250mg |
$110 | 2023-02-17 |
Methyl 4-chloro-6-fluoroquinoline-2-carboxylate Related Literature
-
Eunju Nam,Jiyeon Han,Sunhee Choi,Mi Hee Lim Chem. Commun., 2021,57, 7637-7640
-
Eric Besson,Stéphane Gastaldi,Emily Bloch,Selma Aslan,Hakim Karoui,Olivier Ouari,Micael Hardy Analyst, 2019,144, 4194-4203
-
Domenico Lombardo,Gianmarco Munaò,Pietro Calandra,Luigi Pasqua,Maria Teresa Caccamo Phys. Chem. Chem. Phys., 2019,21, 11983-11991
-
Maomao Hou,Fenglin Zhong,Qiu Jin,Enjiang Liu,Jie Feng,Tengyun Wang,Yue Gao RSC Adv., 2017,7, 34392-34400
-
Jason Y. C. Lim,Yong Yu,Guorui Jin,Kai Li,Yi Lu,Jianping Xie Nanoscale Adv., 2020,2, 3921-3932
Additional information on Methyl 4-chloro-6-fluoroquinoline-2-carboxylate
Comprehensive Overview of Methyl 4-chloro-6-fluoroquinoline-2-carboxylate (CAS No. 301823-61-0)
Methyl 4-chloro-6-fluoroquinoline-2-carboxylate (CAS No. 301823-61-0) is a highly specialized quinoline derivative that has garnered significant attention in pharmaceutical and agrochemical research. This compound, characterized by its unique chloro-fluoro substitution pattern, serves as a critical intermediate in the synthesis of bioactive molecules. Its molecular structure, featuring a methyl ester group at the 2-position, enhances its reactivity and versatility in organic transformations. Researchers are increasingly exploring its potential in drug discovery, particularly for targeting antibacterial and antifungal applications, aligning with the global demand for novel antimicrobial agents.
The growing interest in Methyl 4-chloro-6-fluoroquinoline-2-carboxylate is reflected in its frequent appearance in scientific literature and patent filings. Its CAS No. 301823-61-0 is often searched alongside terms like "quinoline synthesis," "fluoroquinolone precursors," and "heterocyclic building blocks," highlighting its relevance in modern chemistry. The compound’s chloro and fluoro substituents contribute to its electron-deficient nature, making it a valuable scaffold for designing enzyme inhibitors and receptor modulators. This aligns with current trends in precision medicine, where researchers seek tailored solutions for complex diseases.
In the context of green chemistry, Methyl 4-chloro-6-fluoroquinoline-2-carboxylate has been studied for its potential in sustainable synthesis routes. With the rise of environmentally friendly protocols, chemists are optimizing its production to minimize waste and energy consumption. Questions like "How to synthesize Methyl 4-chloro-6-fluoroquinoline-2-carboxylate efficiently?" or "What are the applications of fluorinated quinolines?" are commonly encountered in academic and industrial forums, underscoring its practical significance.
Another area of exploration for CAS No. 301823-61-0 is its role in material science. The quinoline core of this compound exhibits luminescent properties, making it a candidate for organic light-emitting diodes (OLEDs) and sensors. This interdisciplinary appeal bridges the gap between pharmaceuticals and advanced materials, addressing user queries such as "Can quinoline derivatives be used in optoelectronics?" or "What are the latest advances in fluorinated heterocycles?"
From a commercial standpoint, Methyl 4-chloro-6-fluoroquinoline-2-carboxylate is supplied by leading chemical manufacturers under stringent quality controls. Its purity and stability are critical for reproducible results in research, prompting frequent searches for "reliable suppliers of CAS 301823-61-0" and "analytical methods for quinoline derivatives." The compound’s spectroscopic data (e.g., NMR, HPLC) is also widely documented to aid in verification and application studies.
In summary, Methyl 4-chloro-6-fluoroquinoline-2-carboxylate (CAS No. 301823-61-0) stands at the intersection of innovation and utility. Its multifaceted applications—from drug development to functional materials—resonate with contemporary scientific priorities. As interest in fluorinated compounds and heterocyclic chemistry continues to surge, this compound remains a focal point for researchers aiming to address pressing challenges in health and technology.
301823-61-0 (Methyl 4-chloro-6-fluoroquinoline-2-carboxylate) Related Products
- 169674-14-0(1H-Indole-2-carboxylic acid, 5-chloro-6-fluoro-, methyl ester)
- 643044-04-6(Methyl 4,7-dichloroquinoline-2-carboxylate)
- 1150164-82-1(Methyl 4,7-dichloro-8-fluoroquinoline-2-carboxylate)
- 153500-78-8(1H-Indole-2-carboxylic acid, 4-chloro-5-fluoro-, ethyl ester)
- 169674-00-4(Methyl 6-chloro-5-fluoro-1H-indole-2-carboxylate)
- 167631-84-7(Methyl 5-fluoro-1H-indole-2-carboxylate)
- 848501-96-2(Methyl 4,6-dichloroquinoline-2-carboxylate)
- 219949-93-6(2-Quinolinecarboxylicacid, 4-chloro-5,8-difluoro-, methyl ester)
- 86324-52-9(Methyl 6-fluoroquinoline-2-carboxylate)
- 1356126-69-6(Ethyl 6-fluoroquinoline-2-carboxylate)