Cas no 30148-23-3 (1-Methyl-2-(trichloroacetyl)imidazole)

1-Methyl-2-(trichloroacetyl)imidazole is a reactive heterocyclic compound primarily used as an intermediate in organic synthesis. Its key structural features include a trichloroacetyl group attached to an imidazole ring, enhancing its electrophilic properties. This compound is particularly valuable in peptide coupling and acylation reactions due to its high reactivity and selectivity. The trichloroacetyl moiety facilitates efficient activation of carboxylic acids, making it useful in the synthesis of amides and esters. Additionally, its stability under controlled conditions allows for precise handling in laboratory settings. The product is commonly employed in pharmaceutical and agrochemical research, where its robust reactivity supports the development of complex molecular architectures. Proper storage and handling are recommended due to its moisture sensitivity.
1-Methyl-2-(trichloroacetyl)imidazole structure
30148-23-3 structure
Product Name:1-Methyl-2-(trichloroacetyl)imidazole
CAS No:30148-23-3
MF:C6H5Cl3N2O
MW:227.475698232651
MDL:MFCD03789113
CID:2121580
PubChem ID:11299122
Update Time:2025-11-06

1-Methyl-2-(trichloroacetyl)imidazole Chemical and Physical Properties

Names and Identifiers

    • 2,2,2-trichloro-1-(1-methyl-1H-imidazol-2-yl)ethanone
    • 1-Methyl-2-(trichloroacetyl)imidazole
    • 2,2,2-trichloro-1-(1-methyl-1H-imidazol-2-yl)ethan-1-one
    • MODGUAUPMUUXLN-UHFFFAOYSA-N
    • 2-trichloroacetyl-1-methylimidazole
    • FCH1318095
    • NE27106
    • SY046259
    • 1-Methyl-2-(trichloroacetyl)-1H-imidazole
    • Z86499935
    • Ethanone, 2,2,2-trichloro-1-(1-methyl-1H-imidazol-2-yl)-
    • 2-(Trichloroacetyl)-1-methylimidazole; 2,2,2-Trichloro-1-(1-methyl-1H-imidazol-2-yl)ethanone; 1-Methyl-2-(trichloroacetyl)-1H-imidazole;
    • SCHEMBL2031152
    • DB-329515
    • 2,2,2-trichloro-1-(1-methylimidazol-2-yl)ethanone
    • EN300-75725
    • AC1474
    • CS-0197128
    • AC-30389
    • AKOS023166219
    • MFCD03789113
    • 1-?Methyl-?2-?(trichloroacetyl)?imidazole
    • 30148-23-3
    • 978-564-0
    • FBA14823
    • MDL: MFCD03789113
    • Inchi: 1S/C6H5Cl3N2O/c1-11-3-2-10-5(11)4(12)6(7,8)9/h2-3H,1H3
    • InChI Key: MODGUAUPMUUXLN-UHFFFAOYSA-N
    • SMILES: ClC(C(C1=NC=CN1C)=O)(Cl)Cl

Computed Properties

  • Exact Mass: 225.946746g/mol
  • Monoisotopic Mass: 225.946746g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 12
  • Rotatable Bond Count: 1
  • Complexity: 192
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 34.9
  • XLogP3: 1.9

Experimental Properties

  • Density: 1.6±0.1 g/cm3
  • Melting Point: 75-80°C
  • Boiling Point: 272.3±50.0 °C at 760 mmHg
  • Flash Point: 118.5±30.1 °C
  • Vapor Pressure: 0.0±0.6 mmHg at 25°C

1-Methyl-2-(trichloroacetyl)imidazole Security Information

1-Methyl-2-(trichloroacetyl)imidazole Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd.
Y07785-5g
1-?Methyl-?2-?(trichloroacetyl)?imidazole
30148-23-3 95%
5g
¥2029.0 2024-07-16
SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd.
Y07785-10g
1-?Methyl-?2-?(trichloroacetyl)?imidazole
30148-23-3 95%
10g
¥2859.0 2024-07-16
SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd.
Y07785-1g
1-?Methyl-?2-?(trichloroacetyl)?imidazole
30148-23-3 95%
1g
¥739.0 2024-07-16
SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd.
Y07785-25g
1-?Methyl-?2-?(trichloroacetyl)?imidazole
30148-23-3 95%
25g
¥4959.0 2024-07-16
TRC
M327850-250mg
1-?Methyl-?2-?(trichloroacetyl)?imidazole
30148-23-3
250mg
$ 58.00 2023-09-07
TRC
M327850-500mg
1-?Methyl-?2-?(trichloroacetyl)?imidazole
30148-23-3
500mg
$ 75.00 2023-09-07
TRC
M327850-1g
1-?Methyl-?2-?(trichloroacetyl)?imidazole
30148-23-3
1g
$ 109.00 2023-09-07
TRC
M327850-2.5g
1-?Methyl-?2-?(trichloroacetyl)?imidazole
30148-23-3
2.5g
$184.00 2023-05-17
abcr
AB527070-5 g
1-Methyl-2-(trichloroacetyl)imidazole; .
30148-23-3
5g
€127.20 2023-07-11
abcr
AB527070-25 g
1-Methyl-2-(trichloroacetyl)imidazole; .
30148-23-3
25g
€294.50 2023-04-17

Additional information on 1-Methyl-2-(trichloroacetyl)imidazole

Market Research and Analysis Report on 1-Methyl-2-(trichloroacetyl)imidazole (CAS No. 30148-23-3)

The compound 1-Methyl-2-(trichloroacetyl)imidazole, identified by the CAS number 30148-23-3, has garnered significant attention in the chemical and pharmaceutical industries due to its unique properties and potential applications. This report aims to provide a comprehensive analysis of the current market landscape, research advancements, and future prospects for this compound.

Recent studies have highlighted the role of 1-Methyl-2-(trichloroacetyl)imidazole in various chemical reactions, particularly in the synthesis of bioactive molecules. Its trichloroacetyl group imparts reactivity, making it a valuable intermediate in drug discovery and development processes. The compound has been explored for its potential in anti-cancer therapies, where it demonstrates selective cytotoxicity against cancer cells.

Market demand for 1-Methyl-2-(trichloroacetyl)imidazole is driven by its use in academic research and industrial applications. Key regions exhibiting high demand include North America, Europe, and Asia-Pacific, with emerging markets in China and India showing significant growth potential. The compound is widely sourced from global suppliers specializing in fine chemicals and intermediates for pharmaceuticals.

To meet the increasing demand, several manufacturers have optimized their production processes to ensure scalability and cost-effectiveness. Advanced synthetic methodologies, including catalytic asymmetric synthesis and microwave-assisted reactions, have been employed to enhance the purity and yield of the compound. These innovations are expected to further stimulate market growth.

In terms of regulatory considerations, 1-Methyl-2-(trichloroacetyl)imidazole must adhere to stringent safety and quality standards imposed by global regulatory bodies such as the FDA and EMA. Ongoing research focuses on evaluating its toxicity profiles and environmental impact to ensure compliance with sustainability practices.

Looking ahead, the market for 1-Methyl-2-(trichloroacetyl)imidazole is poised for expansion due to increasing investments in drug development pipelines targeting complex diseases. Collaborative efforts between academia and industry are anticipated to accelerate innovation and application development.

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