Cas no 292623-33-7 (2-bromo-1-methylcyclopropane-1-carboxylic acid)

2-Bromo-1-methylcyclopropane-1-carboxylic acid is a cyclopropane derivative featuring a bromine substituent and a carboxylic acid functional group, making it a versatile intermediate in organic synthesis. Its strained cyclopropane ring enhances reactivity, enabling selective transformations in cyclopropylation and ring-opening reactions. The presence of both bromine and carboxylic acid groups allows for further functionalization, including nucleophilic substitutions and coupling reactions. This compound is particularly useful in pharmaceutical and agrochemical research, where cyclopropane motifs are valued for their bioactivity. High purity and well-defined structure ensure reproducibility in synthetic applications. Proper handling is advised due to potential reactivity hazards.
2-bromo-1-methylcyclopropane-1-carboxylic acid structure
292623-33-7 structure
Product Name:2-bromo-1-methylcyclopropane-1-carboxylic acid
CAS No:292623-33-7
MF:C5H7BrO2
MW:179.011881113052
MDL:MFCD00760331
CID:3931449
PubChem ID:5131156
Update Time:2025-11-02

2-bromo-1-methylcyclopropane-1-carboxylic acid Chemical and Physical Properties

Names and Identifiers

    • Cyclopropanecarboxylic acid, 2-bromo-1-methyl-
    • 2-BROMO-1-METHYL-CYCLOPROPANECARBOXYLIC ACID
    • 2-Bromo-1-methylcyclopropane-1-carboxylic acid
    • 2-bromo-1-methylcyclopropane-1-carboxylicacid
    • SCHEMBL20570308
    • EN300-258478
    • SB36414
    • DB-008798
    • CS-0341318
    • trans-2-bromo-1-methylcyclopropanecarboxylic acid
    • 292623-33-7
    • G56318
    • 824-466-7
    • SLA62333
    • 2-bromo-1-methylcyclopropane-1-carboxylic acid
    • MDL: MFCD00760331
    • Inchi: InChI=1S/C5H7BrO2/c1-5(4(7)8)2-3(5)6/h3H,2H2,1H3,(H,7,8)
    • InChI Key: AQAFCWJNUSCJIA-UHFFFAOYSA-N

Computed Properties

  • Exact Mass: 177.96294g/mol
  • Monoisotopic Mass: 177.96294g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 8
  • Rotatable Bond Count: 1
  • Complexity: 134
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 2
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 1.1
  • Topological Polar Surface Area: 37.3?2

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2-bromo-1-methylcyclopropane-1-carboxylic acid Suppliers

Amadis Chemical Company Limited
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(CAS:292623-33-7)2-bromo-1-methylcyclopropane-1-carboxylic acid
Order Number:A1035349
Stock Status:in Stock
Quantity:5g
Purity:99%
Pricing Information Last Updated:Thursday, 29 August 2024 16:56
Price ($):2590.0

Additional information on 2-bromo-1-methylcyclopropane-1-carboxylic acid

Exploring the Versatile Applications and Properties of 2-Bromo-1-methylcyclopropane-1-carboxylic acid (CAS No. 292623-33-7)

2-Bromo-1-methylcyclopropane-1-carboxylic acid (CAS No. 292623-33-7) is a specialized organic compound that has garnered significant attention in pharmaceutical and agrochemical research. This cyclopropane derivative is characterized by its unique structural features, including a bromine substituent and a carboxylic acid functional group, which make it a valuable intermediate in synthetic chemistry. The compound's molecular formula is C5H7BrO2, and it typically appears as a white to off-white crystalline powder under standard conditions.

The growing interest in cyclopropane-containing compounds like 2-bromo-1-methylcyclopropane carboxylic acid stems from their remarkable biological activities and synthetic utility. Researchers are particularly interested in how the strained three-membered ring system influences the compound's reactivity and potential applications. Recent studies have shown that such structures can serve as key building blocks for developing novel pharmaceutical ingredients and crop protection agents, aligning with current trends in drug discovery and sustainable agriculture.

From a chemical perspective, 2-bromo-1-methylcyclopropane-1-carboxylic acid exhibits several noteworthy properties. The presence of both electron-withdrawing (bromine) and electron-donating (methyl) groups creates an interesting electronic environment that affects its reactivity patterns. This makes the compound particularly useful in ring-opening reactions and nucleophilic substitution processes, which are fundamental transformations in organic synthesis. The carboxylic acid moiety further enhances its versatility, allowing for various derivatization strategies.

In pharmaceutical applications, 2-bromo-1-methylcyclopropane-1-carboxlic acid derivatives have shown promise as potential precursors for bioactive molecules. The cyclopropane ring is a privileged structure in medicinal chemistry, often contributing to improved metabolic stability and binding affinity when incorporated into drug candidates. Current research explores its use in developing treatments for neurological disorders and inflammatory conditions, addressing some of today's most pressing healthcare challenges.

The agrochemical sector has also recognized the value of brominated cyclopropane compounds. These structures have demonstrated effectiveness as intermediates for novel pesticides and herbicides, particularly in formulations targeting resistant pest strains. With increasing global focus on sustainable farming practices and reduced environmental impact, compounds like 2-bromo-1-methylcyclopropane-1-carboxylic acid are being investigated for their potential in next-generation crop protection solutions.

From a synthetic chemistry standpoint, CAS 292623-33-7 offers numerous advantages. Its well-defined reactivity profile enables controlled transformations, making it attractive for structure-activity relationship studies and molecular design projects. The compound's stability under various conditions allows for flexible handling and storage, though standard precautions for handling organic bromides should always be observed.

Market trends indicate growing demand for specialized cyclopropane derivatives like 2-bromo-1-methylcyclopropane-1-carboxylic acid. Pharmaceutical and agrochemical companies are increasingly seeking novel chemical entities to address complex challenges in drug development and crop protection. This has led to expanded research into the compound's potential applications and improved synthetic methodologies for its production.

Quality control and analytical characterization of 2-bromo-1-methylcyclopropane carboxylic acid typically involve advanced techniques such as HPLC, NMR spectroscopy, and mass spectrometry. These methods ensure the compound meets the stringent purity requirements for research and industrial applications. Proper characterization is particularly important given the compound's role as an intermediate in multi-step synthetic sequences.

Environmental and safety considerations for 2-bromo-1-methylcyclopropane-1-carboxylic acid follow standard protocols for handling organic compounds. While not classified as highly hazardous, appropriate laboratory practices should be maintained during its use. Researchers are increasingly interested in developing greener synthetic routes to such compounds, reflecting the chemical industry's broader sustainability initiatives.

Future research directions for CAS 292623-33-7 may explore its potential in emerging fields like bioconjugation chemistry and materials science. The unique properties of the cyclopropane ring system continue to inspire innovative applications across multiple disciplines. As synthetic methodologies advance, we can anticipate new discoveries regarding this compound's utility and novel derivatives with enhanced properties.

For researchers and industry professionals seeking reliable information about 2-bromo-1-methylcyclopropane-1-carboxylic acid, it's important to consult up-to-date scientific literature and reputable suppliers. The compound's specialized nature means that proper handling protocols and application-specific considerations should always be followed to ensure optimal results in research and development projects.

Recommended suppliers
Amadis Chemical Company Limited
(CAS:292623-33-7)2-bromo-1-methylcyclopropane-1-carboxylic acid
A1035349
Purity:99%
Quantity:5g
Price ($):2590.0
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