Cas no 28957-04-2 (Oridonin)

Oridonin is a bioactive triterpenoid extracted from the plant Isodon rubescens, exhibiting potent anti-inflammatory and immunosuppressive properties. Its key advantages include reduced pro-inflammatory cytokine production, inhibition of NF-κB activation, and potential therapeutic applications in treating autoimmune diseases and inflammatory disorders.
Oridonin structure
Oridonin structure
Product Name:Oridonin
CAS No:28957-04-2
MF:C20H28O6
MW:364.4327
MDL:MFCD00221762
CID:53402
PubChem ID:29927679
Update Time:2025-10-21

Oridonin Chemical and Physical Properties

Names and Identifiers

    • Oridonin
    • ISODONAL
    • (1S,4AR,5S,6S,14S)-1,5,6,14-Tetrahydroxy-4,4-dimethyl-8-methylenedecahydro-1H-6,11b-(epoxymethano)-6a,9-methanocyclohepta[a]naphthalen-7(8H)-one
    • RUBESCENSIN A
    • (14r)-7-alpha,20-epoxy-1-alpha,6-beta,7,14-tetrahydroxykaur-16-en-15-one
    • (1-alpha,6-beta,7-alpha,14r)-7,20-epoxy-1,6,7,14-tetrahydroxykaur-16-en-15-o
    • 20-epoxy-1-alpha,6-beta,7,14-tetrahydroxy-7-alph(14r)-kaur-16-en-15-on
    • Kaur-16-en-15-one, 7,20-epoxy-1,6,7,14-tetrahydroxy-, (1a,6b,7a,14R)-
    • ORIDONIN (RG)
    • RUBESCENSIN A(RG)
    • 7a,20-Epoxy-1a,6b,7,14-tetrahydroxy-Kaur-16-en-15-one Isodonol
    • Isodonol
    • megathyrin A
    • Rabdosia rubescens
    • Rubescensin
    • MLS003115310
    • CO0038
    • SMR001830890
    • 9,10,15,18-Tetrahydroxy-12,12-dimethyl-6-methylidene-17-oxapentacyclo[7.6.2.15,8.01,11.02,8]octadeca
    • 9,10,15,18-Tetrahydroxy-12,12-dimethyl-6-methylidene-17-oxapentacyclo[7.6.2.15,8.01,11.02,8]octadecan-7-one
    • A876572
    • AS-15421
    • CHEBI:138236
    • 0APJ98UCLQ
    • CHEMBL1164920
    • KAUR-16-EN-15-ONE, 7-alpha,20-EPOXY-1-alpha,6-beta,7,14-TETRAHYDROXY-, (14R)-
    • 28957-04-2
    • AKOS025310967
    • ORIDONIN [INCI]
    • PURE ORIDONIN
    • KAUR-16-EN-15-ONE, 7,20-EPOXY-1,6,7,14-TETRAHYDROXY-, (1.ALPHA.,6.BETA.,7.ALPHA.,14R)-
    • CS-0007086
    • NSC 250682
    • H10339
    • A,6
    • Z2037317501
    • Kaur-16-en-15-one, 7,20-epoxy-1,6,7,14-tetrahydroxy-, (1alpha,6beta,7alpha,14R)-
    • (1alpha,6beta,7alpha,14R)-7,20-epoxy-1,6,7,14-tetrahydroxykaur-16-en-15-one
    • A,14R)-1,5,6,14-Tetrahydroxy-4,4-dimethyl-8-methylenedecahydro-1H-6,11b-(epoxymethano)-6a,9-methanocyclohepta[a]naphthalen-7(8H)-one
    • SCHEMBL19217133
    • A,7
    • (1
    • NSC-250682
    • Q27236543
    • Curator_000006
    • BDBM50605174
    • CCG-208386
    • Oridonine
    • O0387
    • Rubescenin
    • (1-alpha,6-beta,7-alpha,14R)-7,20-Epoxy-1,6,7,14-tetrahydroxykaur-16-en-15-one
    • (1alpha,5beta,6beta,7alpha,8alpha,9beta,10alpha,13alpha,14R)-1,6,7,14-tetrahydroxy-7,20-epoxykaur-16-en-15-one
    • DTXSID201021760
    • 7?,20-Epoxy-1?,6?,7,14-tetrahydroxykaur-16-en-15-one
    • NSC-250682; Isodonol
    • KAUR-16-EN-15-ONE, 7.ALPHA.,20-EPOXY-1.ALPHA.,6.BETA.,7,14-TETRAHYDROXY-, (14R)-
    • HY-N0004
    • UNII-0APJ98UCLQ
    • Ent-Oridonin
    • CHEMBL454570
    • SCHEMBL16283627
    • AKOS040737172
    • Compound NP-024372
    • BDBM50575106
    • Oridonin,(S)
    • LS-14810
    • 7a,20-Epoxy-1a,6b,7,14-tetrahydroxy-Kaur-16-en-15-one; oridonin; rubescensin A
    • CHEMBL1980693
    • 28957-10-0
    • FT-0654913
    • 18288-82-9
    • SCHEMBL13533177
    • lasidonin
    • AKOS032949870
    • SCHEMBL24209226
    • MLSMR
    • ISODONOL ORIDONIN Oridonin Kaur-16-en-15-one, 7,20-epoxy-1,6,7,14-tetrahydroxy-, (1a,6b,7a,14R)-
    • Oridonin,98%
    • MDL: MFCD00221762
    • Inchi: 1S/C20H28O6/c1-9-10-4-5-11-18-8-26-20(25,19(11,14(9)22)15(10)23)16(24)13(18)17(2,3)7-6-12(18)21/h10-13,15-16,21,23-25H,1,4-8H2,2-3H3
    • InChI Key: SDHTXBWLVGWJFT-UHFFFAOYSA-N
    • SMILES: O1C([H])([H])C23C([H])(C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C2([H])C([H])(C1(C12C(C(=C([H])[H])C([H])(C([H])([H])C([H])([H])C31[H])C2([H])O[H])=O)O[H])O[H])O[H]

Computed Properties

  • Exact Mass: 364.18900
  • Monoisotopic Mass: 364.188589
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 4
  • Hydrogen Bond Acceptor Count: 6
  • Heavy Atom Count: 26
  • Rotatable Bond Count: 0
  • Complexity: 717
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 4
  • Undefined Atom Stereocenter Count : 5
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 107
  • Isotope Atom Count: 0
  • XLogP3: 0.1
  • Topological Polar Surface Area: 107
  • Molecular Weight: 364.4

Experimental Properties

  • Color/Form: Colorless prismatic crystals
  • Density: 1.42g/cm3
  • Melting Point: 248-250 oC
  • Boiling Point: 599.8℃/760mmHg
  • Flash Point: 215°C
  • Refractive Index: 1.635
  • Solubility: DMSO: >20mg/mL
  • PSA: 107.22000
  • LogP: 0.37560
  • Vapor Pressure: 6.9E-17mmHg at 25°C

Oridonin Security Information

  • Symbol: GHS08
  • Signal Word:Warning
  • Hazard Statement: H351
  • Warning Statement: P281
  • WGK Germany:2
  • Hazard Category Code: 40
  • Safety Instruction: 36/37-24/25
  • RTECS:NZ8177000
  • Hazardous Material Identification: Xn
  • Storage Condition:Powder -20°C 3 years ? 4°C 2 years In solvent -80°C 6 months ? -20°C 1 month

Oridonin Customs Data

  • Customs Data:

    China Customs Code:

    2942000000

Oridonin Pricemore >>

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Oridonin Suppliers

Amadis Chemical Company Limited
Gold Member
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(CAS:28957-04-2)Oridonin
Order Number:A876572
Stock Status:in Stock
Quantity:1g/5g
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 09:50
Price ($):178.0/624.0
Hubei Cuiyuan Biotechnology Co.,Ltd
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(CAS:28957-04-2)Oridonin
Order Number:CRN0381
Stock Status:in stock
Quantity:5mg/20mg/50mg
Purity:≥98%
Pricing Information Last Updated:Friday, 14 March 2025 10:55
Price ($):
NewCan Biotech Limited
Gold Member
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(CAS:28957-04-2)Oridonin
Order Number:NC12000
Stock Status:
Quantity:10g
Purity:97%
Pricing Information Last Updated:Friday, 18 July 2025 16:07
Price ($):Price inquiry
Tiancheng Chemical (Jiangsu) Co., Ltd
Gold Member
Audited Supplier Audited Supplier
(CAS:28957-04-2)Oridonin
Order Number:LE1121
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 11:40
Price ($):discuss personally

Oridonin Spectrogram

13C NMR
13C NMR
1H NMR 300 MHz DMSO
1H NMR
Recommended suppliers
Amadis Chemical Company Limited
(CAS:28957-04-2)Oridonin
A876572
Purity:99%/99%
Quantity:1g/5g
Price ($):178.0/624.0
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Hubei Cuiyuan Biotechnology Co.,Ltd
(CAS:28957-04-2)Oridonin
CRN0381
Purity:≥98%
Quantity:5mg/20mg/50mg
Price ($):Inquiry
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