Cas no 2885-79-2 (N-Propionyl-L-cysteine)

N-Propionyl-L-cysteine (NPLC) is a modified derivative of the amino acid L-cysteine, featuring a propionyl group attached to the nitrogen atom. This structural modification enhances its stability and bioavailability compared to conventional L-cysteine. NPLC acts as a precursor to glutathione, supporting cellular antioxidant defense mechanisms. It exhibits mucolytic and cytoprotective properties, making it useful in research and therapeutic applications, particularly in conditions involving oxidative stress or respiratory dysfunction. Its improved pharmacokinetic profile allows for more efficient absorption and utilization. NPLC is commonly employed in biochemical studies and pharmaceutical formulations, where its thiol group reactivity and antioxidant capacity are leveraged for experimental or clinical purposes.
N-Propionyl-L-cysteine structure
N-Propionyl-L-cysteine structure
Product Name:N-Propionyl-L-cysteine
CAS No:2885-79-2
MF:C6H11NO3S
MW:177.22100
CID:267947
PubChem ID:151048
Update Time:2025-05-27

N-Propionyl-L-cysteine Chemical and Physical Properties

Names and Identifiers

    • L-Cysteine,N-(1-oxopropyl)-
    • N-Propionyl-L-cysteine
    • N-Propionyl-L-cystei
    • N-PROPIONYL-L-CYSTEINE, CRM STANDARD
    • (2R)-2-(propanoylamino)-3-sulfanylpropanoic acid
    • L-Cysteine, N-(1-oxopropyl)-
    • (R)-3-Mercapto-2-propionamidopropanoic acid
    • DTXCID20105546
    • SCHEMBL1804546
    • DTXSID10183055
    • DB-266554
    • AKOS006311935
    • J-017300
    • N-Propionylcysteine
    • (2R)-2-PROPANAMIDO-3-SULFANYLPROPANOIC ACID
    • 2885-79-2
    • N-propionylcystein
    • Inchi: InChI=1S/C6H11NO3S/c1-2-5(8)7-4(3-11)6(9)10/h4,11H,2-3H2,1H3,(H,7,8)(H,9,10)/t4-/m0/s1
    • InChI Key: KBBJNRLWAGIQLW-BYPYZUCNSA-N
    • SMILES: SC[C@@H](C(=O)O)NC(CC)=O

Computed Properties

  • Exact Mass: 177.04600
  • Monoisotopic Mass: 177.04596439g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 3
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 4
  • Complexity: 160
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 1
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: -0.1
  • Topological Polar Surface Area: 67.4?2

Experimental Properties

  • PSA: 105.20000
  • LogP: 0.28650

N-Propionyl-L-cysteine Pricemore >>

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