Cas no 28832-07-7 (L-Dicentrine)

L-Dicentrine is a naturally occurring aporphine alkaloid derived from certain plant species, notably within the Lauraceae family. It exhibits notable pharmacological properties, including potential anti-inflammatory, analgesic, and antitumor activities. Structurally characterized by its aporphine backbone, L-Dicentrine interacts with various biological targets, such as dopamine receptors and serotonin systems, making it a subject of interest in neuropharmacology research. Its high purity and well-defined stereochemistry ensure consistency in experimental and therapeutic applications. As a reference standard or research compound, L-Dicentrine is valued for its reproducibility and relevance in studying alkaloid-mediated biological pathways. Proper handling and storage are recommended to maintain stability.
L-Dicentrine structure
L-Dicentrine structure
Product Name:L-Dicentrine
CAS No:28832-07-7
MF:C20H21NO4
MW:339.38504576683
CID:257672
PubChem ID:317843
Update Time:2025-11-02

L-Dicentrine Chemical and Physical Properties

Names and Identifiers

    • 5H-Benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline,6,7,7a,8-tetrahydro-10,11-dimethoxy-7-methyl-, (7aR)-
    • L-Dicentrine
    • 5H-Benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline,6,7,7a,8-tetrahydro-10,11-dimethoxy-7-methyl-,...
    • Eximine
    • O-methyl-phanostenine
    • 28832-07-7
    • NSC-251699
    • (-)-Dicentrine
    • CHEMBL478754
    • 5O9KK11109
    • Dicentrine L-form [MI]
    • AKOS040744558
    • cid_317843
    • NSC 251699
    • (R)-10,11-dimethoxy-7-methyl-6,7,7a,8-tetrahydro-5H-[1,3]dioxolo[4',5':4,5]benzo[1,2,3-de]benzo[g]quinoline
    • 5H-Benzo(g)-1,3-benzodioxolo(6,5,4-de)quinoline, 6,7,7a,8-tetrahydro-10,11-dimethoxy-7-methyl-, (7aR)-
    • SMR000156300
    • 5H-Benzo[g]-1,5,4-de]quinoline, 6,7,7a,8-tetrahydro-10,11-dimethoxy-7-methyl-, (R)-
    • HMS2223B12
    • NCGC00247614-01
    • Dicentrine, (-)-
    • MLS000575015
    • BDBM70841
    • UNII-5O9KK11109
    • (R)-(-)-Dicentrine
    • (12R)-16,17-dimethoxy-11-methyl-3,5-dioxa-11-azapentacyclo[10.7.1.02,6.08,20.014,19]icosa-1(20),2(6),7,14,16,18-hexaene
    • (12R)-16, 17-dimethoxy-11-methyl-3, 5-dioxa-11-azapentacyclo[10.7.1.02, 6.08, 20.014, 19]icosa-1(20), 2(6), 7, 14, 16, 18-hexaene
    • DICENTRINE-(-)
    • NSC251699
    • Q27262635
    • NCI60_002017
    • Dicentrine
    • O,N-Dimethyllitseferine
    • d-Dicentrine
    • HY-N2105
    • (12R)-16,17-dimethoxy-11-methyl-3,5-dioxa-11-azapentacyclo(10.7.1.02,6.08,20.014,19)icosa-1(20),2(6),7,14,16,18-hexaene
    • CS-0018626
    • DICENTRINE L-FORM
    • TS-08094
    • YJWBWQWUHVXPNC-CQSZACIVSA-N
    • Inchi: 1S/C20H21NO4/c1-21-5-4-11-7-17-20(25-10-24-17)19-13-9-16(23-3)15(22-2)8-12(13)6-14(21)18(11)19/h7-9,14H,4-6,10H2,1-3H3/t14-/m1/s1
    • InChI Key: YJWBWQWUHVXPNC-CQSZACIVSA-N
    • SMILES: O1COC2=CC3CCN(C)[C@@H]4CC5C=C(C(=CC=5C(=C12)C4=3)OC)OC

Computed Properties

  • Exact Mass: 339.14700
  • Monoisotopic Mass: 339.14705815g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 5
  • Heavy Atom Count: 25
  • Rotatable Bond Count: 2
  • Complexity: 502
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 1
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 3.2
  • Topological Polar Surface Area: 40.2?2

Experimental Properties

  • Density: 1.266±0.06 g/cm3 (20 oC 760 Torr),
  • Solubility: Almost insoluble (0.011 g/l) (25 o C),
  • PSA: 40.16000
  • LogP: 3.12250

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L-Dicentrine Production Method

Additional information on L-Dicentrine

Comprehensive Overview of L-Dicentrine (CAS No. 28832-07-7): Properties, Applications, and Research Insights

L-Dicentrine (CAS No. 28832-07-7) is a naturally occurring alkaloid derived from the Lauraceae family of plants, particularly found in species like Lindera aggregata and Dicentra. This bioactive compound has garnered significant attention in recent years due to its potential therapeutic properties and applications in traditional medicine and modern pharmacology. Researchers are increasingly exploring its anti-inflammatory, antioxidant, and neuroprotective effects, aligning with the growing consumer interest in natural remedies and plant-based therapeutics.

The chemical structure of L-Dicentrine features a tetrahydroisoquinoline backbone, which is common among alkaloids with biological activity. Its molecular formula, C20H21NO4, and precise stereochemistry contribute to its unique interactions with enzymatic pathways and receptor sites. This specificity makes it a subject of interest for drug discovery and pharmacological research, particularly in addressing conditions like cardiovascular diseases and neurodegenerative disorders—topics frequently searched by users exploring alternative treatments.

In traditional Chinese medicine (TCM), L-Dicentrine-containing plants have been used for centuries to alleviate pain and improve circulation. Modern studies validate these uses, showing its ability to modulate calcium channels and adrenergic receptors. These findings resonate with current trends in integrative medicine, where users often search for evidence-based herbal supplements or synergistic therapies combining conventional and natural approaches.

From a biotechnological perspective, L-Dicentrine is also being investigated for its role in sustainable drug production. With increasing demand for eco-friendly pharmaceuticals, researchers are optimizing extraction methods and synthetic biosynthesis to enhance yield while minimizing environmental impact. This aligns with the rising popularity of green chemistry and circular economy principles in scientific communities.

Quality control of L-Dicentrine (CAS No. 28832-07-7) involves advanced analytical techniques like HPLC and mass spectrometry to ensure purity and consistency—a critical factor for pharmaceutical-grade applications. Consumers and manufacturers alike prioritize standardized extracts, as reflected in frequent searches for lab-tested natural compounds and certified ingredients in dietary supplements.

Ongoing clinical trials are exploring L-Dicentrine's potential in metabolic syndrome management, a hot topic given global concerns about obesity-related diseases. Preliminary data suggest it may influence lipid metabolism and glucose homeostasis, making it relevant to discussions on functional foods and nutraceuticals—keywords often associated with preventive healthcare searches.

In summary, L-Dicentrine represents a bridge between ethnopharmacology and cutting-edge science. Its multifaceted applications—from cardiovascular support to neuroprotection—cater to the increasing demand for multitarget therapeutics. As research progresses, this compound is poised to play a pivotal role in personalized medicine and healthspan extension, two of the most searched topics in contemporary biomedical innovation.

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