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  Tao Wang,Yangyang Liu,Yue Deng,Hongbo Fu,Jianmin Chen Environ. Sci.: Nano, 2018,5, 1821-1833
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  Xiaoming Liu,Zachary D. Hood,Wangda Li,Donovan N. Leonard,Arumugam Manthiram,Miaofang Chi J. Mater. Chem. A, 2021,9, 2111-2119
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• Solvents and Organic Chemicals Organic Compounds Organic acids and derivatives Carboxylic acids and derivatives Carboxylic acid esters
• Solvents and Organic Chemicals Organic Compounds Organic acids and derivatives Carboxylic acids and derivatives Carboxylic acid derivatives Carboxylic acid esters

Recent Advances in the Application of 287174-32-7 and Tert-butyl 2-(2-hydroxyethoxy)acetate in Chemical Biology and Pharmaceutical Research

The chemical compound with the CAS number 287174-32-7 and the product Tert-butyl 2-(2-hydroxyethoxy)acetate have garnered significant attention in recent chemical biology and pharmaceutical research. These compounds are pivotal in the synthesis of novel drug candidates and intermediates, particularly in the development of small molecule therapeutics. This research brief aims to summarize the latest findings and applications of these compounds, highlighting their roles in advancing drug discovery and development.

Recent studies have demonstrated that 287174-32-7 serves as a critical intermediate in the synthesis of biologically active molecules. Its unique chemical properties, including stability and reactivity, make it an ideal candidate for constructing complex pharmacophores. Researchers have utilized this compound in the development of kinase inhibitors, which are essential for targeting various cancers and inflammatory diseases. The ability to modify its structure has opened new avenues for creating more potent and selective inhibitors.

Tert-butyl 2-(2-hydroxyethoxy)acetate, on the other hand, has been extensively studied for its role as a protecting group and a building block in organic synthesis. Its application in peptide and prodrug synthesis has been particularly noteworthy. Recent publications have highlighted its use in improving the bioavailability and pharmacokinetic properties of therapeutic agents. For instance, it has been employed in the design of prodrugs that enhance the delivery of active pharmaceutical ingredients to target tissues, thereby reducing systemic toxicity.

One of the most promising applications of these compounds is in the field of targeted drug delivery. Researchers have developed nanocarriers functionalized with derivatives of 287174-32-7 and Tert-butyl 2-(2-hydroxyethoxy)acetate to achieve site-specific drug release. These advancements have shown remarkable efficacy in preclinical models, particularly in treating solid tumors and chronic inflammatory conditions. The ability to tailor the release kinetics of therapeutic agents has significantly improved treatment outcomes.

In addition to their therapeutic applications, these compounds have also been explored for their potential in diagnostic imaging. The incorporation of 287174-32-7 into fluorescent probes has enabled real-time visualization of biological processes at the molecular level. Similarly, Tert-butyl 2-(2-hydroxyethoxy)acetate has been used to modify contrast agents, enhancing their stability and imaging capabilities. These innovations are paving the way for more accurate and non-invasive diagnostic techniques.

Despite these advancements, challenges remain in the large-scale production and optimization of these compounds. Recent efforts have focused on developing greener synthetic routes to minimize environmental impact and reduce production costs. Catalytic methods and flow chemistry have emerged as viable solutions, offering higher yields and better control over reaction conditions. These developments are expected to facilitate the broader adoption of these compounds in industrial and clinical settings.

In conclusion, the compounds 287174-32-7 and Tert-butyl 2-(2-hydroxyethoxy)acetate continue to play a vital role in chemical biology and pharmaceutical research. Their versatility and efficacy in drug design, targeted delivery, and diagnostic imaging underscore their importance in advancing modern medicine. Future research should focus on overcoming existing limitations and exploring new applications to fully realize their potential.

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• 17640-23-2(tert-butyl methoxyacetate)
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• 120289-22-7(2-2-(tert-Butoxy)-2-oxoethoxyacetic Acid)
• 55666-48-3(tert-butyl 2-(tert-butoxy)acetate)
• 518044-31-0(Tert-Butyl 2-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)acetate)