Cas no 28544-93-6 (1,4-dioxepan-6-one)

1,4-Dioxepan-6-one is a cyclic ester (lactone) with a seven-membered ring structure, offering unique reactivity in polymerization and organic synthesis. Its ring-opening polymerization yields biodegradable polyesters with potential applications in medical and environmental fields. The compound's strained ring system facilitates controlled polymerization, enabling precise molecular weight control and tailored material properties. Its oxygen-rich structure enhances compatibility with polar substrates, making it useful in copolymerization to modify material characteristics. 1,4-Dioxepan-6-one is also employed as a versatile intermediate in fine chemical synthesis, particularly for introducing ester functionalities. Handling requires standard precautions for lactones, including moisture control to prevent premature hydrolysis.
1,4-dioxepan-6-one structure
1,4-dioxepan-6-one structure
Product Name:1,4-dioxepan-6-one
CAS No:28544-93-6
MF:C5H8O3
MW:116.115221977234
MDL:MFCD11865273
CID:819888
PubChem ID:46856376
Update Time:2025-10-24

1,4-dioxepan-6-one Chemical and Physical Properties

Names and Identifiers

    • 4-dioxepan-6-one
    • LogP
    • 1,4-Dioxepan-6-one
    • [1,4]Dioxepan-6-one
    • DTXSID00676800
    • SCHEMBL3727885
    • ZBEJPWPZAMESBJ-UHFFFAOYSA-N
    • DB-086637
    • AT36791
    • 28544-93-6
    • EN300-92185
    • AKOS015918359
    • 1,4-dioxepan-6-one
    • MDL: MFCD11865273
    • Inchi: 1S/C5H8O3/c6-5-3-7-1-2-8-4-5/h1-4H2
    • InChI Key: ZBEJPWPZAMESBJ-UHFFFAOYSA-N
    • SMILES: O1CC(COCC1)=O

Computed Properties

  • Exact Mass: 116.04734
  • Monoisotopic Mass: 116.047344113g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 8
  • Rotatable Bond Count: 0
  • Complexity: 79.7
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: -0.4
  • Topological Polar Surface Area: 35.5?2

Experimental Properties

  • PSA: 35.53

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1,4-dioxepan-6-one Suppliers

Amadis Chemical Company Limited
Gold Member
Audited Supplier Audited Supplier
(CAS:28544-93-6)1,4-dioxepan-6-one
Order Number:A1084865
Stock Status:in Stock
Quantity:1g
Purity:99%
Pricing Information Last Updated:Thursday, 29 August 2024 19:22
Price ($):709.0

1,4-dioxepan-6-one Related Literature

Additional information on 1,4-dioxepan-6-one

Comprehensive Guide to 1,4-Dioxepan-6-one (CAS No. 28544-93-6): Properties, Applications, and Industry Insights

1,4-Dioxepan-6-one (CAS No. 28544-93-6) is a cyclic ester with a unique molecular structure, making it a versatile compound in polymer chemistry and specialty materials. Its seven-membered ring and lactone functionality have garnered attention for applications ranging from biodegradable plastics to pharmaceutical intermediates. As sustainability and green chemistry dominate global discussions, researchers are increasingly exploring 1,4-dioxepan-6-one derivatives for eco-friendly alternatives to conventional polymers.

The compound’s thermal stability and reactivity make it a valuable monomer for synthesizing poly(1,4-dioxepan-6-one), a material studied for its potential in medical devices and controlled-release drug delivery systems. Recent studies highlight its compatibility with ring-opening polymerization (ROP) techniques, a hot topic in materials science due to its precision in creating tailored macromolecules. Searches for "biodegradable lactones 2024" or "ROP monomers for medical applications" reflect growing interest in this niche.

From an industrial perspective, 1,4-dioxepan-6-one is often compared to ε-caprolactone and lactide, two widely used lactones. However, its lower melting point and enhanced solubility in organic solvents offer distinct advantages in formulation flexibility. Manufacturers focusing on high-performance coatings or adhesives frequently evaluate its incorporation to improve product properties. Keywords like "sustainable polymer additives" and "cyclic ester reactivity" align with current market trends.

Analytical characterization of CAS 28544-93-6 typically involves NMR spectroscopy and mass spectrometry to confirm purity and structural integrity. Quality control protocols emphasize the absence of residual solvents, a critical factor for pharmaceutical-grade applications. For researchers, questions such as "How to synthesize 1,4-dioxepan-6-one?" or "Safety data sheet for 28544-93-6" are common search queries, underscoring the need for accessible technical documentation.

Emerging applications in 3D printing resins and bio-based composites further expand the compound’s relevance. As circular economy principles gain traction, 1,4-dioxepan-6-one’s biodegradability profile positions it as a candidate for next-generation materials. Industry reports on "green polymer innovations" often cite its potential, driving demand for specialized suppliers. Regulatory compliance, particularly regarding REACH and FDA approvals, remains a key consideration for commercial adoption.

In summary, 1,4-dioxepan-6-one (CAS No. 28544-93-6) bridges academic research and industrial innovation, with its utility spanning from advanced material science to sustainable chemistry. Its alignment with global priorities—such as reducing carbon footprints and developing safer biomaterials—ensures continued exploration and optimization in the coming decade.

Recommended suppliers
Amadis Chemical Company Limited
(CAS:28544-93-6)1,4-dioxepan-6-one
A1084865
Purity:99%
Quantity:1g
Price ($):709.0
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