• 1. An integrated digital microfluidic chip for multiplexed proteomic sample preparation and analysis by MALDI-MS?
  Hyejin Moon,Aaron R. Wheeler,Robin L. Garrell,Chang-Jin “CJ” Kim Lab Chip, 2006,6, 1213-1219
• 2. An aptasensor for the detection of ampicillin in milk using a personal glucose meter
  Xixi Li,Nanwei Zhu,Ruohan Li,Qinpu Zhang Anal. Methods, 2020,12, 3376-3381
• 3. Alt-proteins: A promising future
• 4. An autonomous self-optimizing flow machine for the synthesis of pyridine–oxazoline (PyOX) ligands?
  Eric Wimmer,Daniel Cortés-Borda,Solène Brochard,Elvina Barré,Charlotte Truchet,Fran?ois-Xavier Felpin React. Chem. Eng., 2019,4, 1608-1615
• 5. An all-solid-state asymmetric device based on a polyaniline hydrogel for a high energy flexible supercapacitor?
  Hamid Heydari,Mohammad B. Gholivand New J. Chem., 2017,41, 237-244

• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Acylaminobenzoic acid and derivatives
• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Benzoic acids and derivatives Acylaminobenzoic acid and derivatives

3-(Isobutyrylamino)benzoic Acid (CAS No 28533-44-0): A Comprehensive Overview

3-(Isobutyrylamino)benzoic acid, a compound with the CAS registry number 28533-44-0, has garnered significant attention in the fields of organic chemistry and materials science due to its unique structural properties and versatile applications. This compound, also referred to as isobutyramide benzoic acid derivative, is a derivative of benzoic acid with an isobutyryl amino group attached at the third position of the benzene ring. Its molecular formula is C11H15NO2, and it has a molecular weight of 197.24 g/mol.

The synthesis of 3-(isobutyrylamino)benzoic acid involves a series of well-established organic reactions, including nucleophilic substitution and condensation processes. Recent advancements in catalytic methods have enabled the efficient production of this compound with high purity, making it more accessible for research and industrial applications.

One of the most notable aspects of 3-(isobutyrylamino)benzoic acid is its role in drug discovery and development. The compound has been extensively studied for its potential as a building block in medicinal chemistry, particularly in the design of bioactive molecules targeting various therapeutic areas such as cancer, inflammation, and infectious diseases. Its ability to form stable amide bonds with other functional groups makes it an ideal candidate for constructing complex molecular architectures.

Recent studies have highlighted the importance of isobutyramide benzoic acid derivatives in enhancing the pharmacokinetic properties of drugs, such as improving bioavailability and reducing toxicity. For instance, researchers have demonstrated that incorporating isobutyryl amino groups into drug molecules can significantly enhance their solubility and permeability across biological membranes.

In addition to its medicinal applications, 3-(isobutyrylamino)benzoic acid has found utility in materials science, particularly in the development of advanced polymers and coatings. The compound's ability to form robust amide linkages makes it suitable for synthesizing high-performance materials with tailored mechanical and thermal properties.

From a structural standpoint, the presence of the isobutyryl amino group introduces steric hindrance and electronic effects that influence the compound's reactivity and stability. These properties have been leveraged in various chemical transformations, including cross-coupling reactions and polymerizations.

The latest research on CAS No 28533-44-0 has focused on its application in sustainable chemistry, particularly in developing eco-friendly synthesis routes that minimize waste and energy consumption. Green chemistry approaches, such as using microwave-assisted synthesis or enzymatic catalysis, have been explored to produce this compound more efficiently while reducing environmental impact.

In conclusion, 3-(isobutyrylamino)benzoic acid (CAS No 28533-44-0) stands out as a versatile and valuable compound with diverse applications across multiple disciplines. Its unique chemical properties, combined with recent advancements in synthesis and application techniques, position it as a key player in future innovations within organic chemistry and related fields.

• 76208-99-6(3-(propionylamino)benzoic Acid)
• 19313-85-0(4-(propionylamino)benzoic Acid)
• 76209-00-2(3-(Butyrylamino)benzoic Acid)
• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)