Cas no 28328-54-3 (Desbutyl Bumetanide)
Desbutyl Bumetanide is a metabolite of the loop diuretic bumetanide, formed through the oxidative removal of the butyl side chain. This compound retains pharmacological activity as a sulfamoyl benzoic acid derivative, though with altered potency and pharmacokinetic properties compared to the parent molecule. Its primary advantage lies in its role as a reference standard in analytical studies, enabling precise quantification and metabolic profiling of bumetanide in biological matrices. Desbutyl Bumetanide is also of interest in research exploring structure-activity relationships of diuretics, particularly regarding renal transport mechanisms. The compound's defined structure and purity make it valuable for method validation in clinical and forensic toxicology.
Desbutyl Bumetanide structure
Product Name:Desbutyl Bumetanide
CAS No:28328-54-3
MF:C13H12N2O5S
MW:308.309782028198
CID:282500
PubChem ID:119927
Update Time:2025-06-07
Desbutyl Bumetanide Chemical and Physical Properties
Names and Identifiers
-
- Benzoic acid,3-amino-5-(aminosulfonyl)-4-phenoxy-
- Desbutyl Bumetanide
- 3-amino-5-(aminosulfonyl)-4-phenoxybenzoic acid
- 3-amino-4-phenoxy-5-sulfamoyl-benzoic acid
- 3-amino-4-phenoxy-5-sulfamylbenzoic acid
- 3-amino-4-phenoxy-5-sulfamyl-benzoic acid
- 3-amino-4-phenoxy-5-sulphamyl-benzoic acid
- 3-Amino-5-(aminosulphonyl)-4-phenoxybenzoic acid
- 3-sulphamoyl-4-phenoxy-5-amino-benzoic acid
- AC1L3PRB
- AC1Q6UWR
- CTK4G1251
- EINECS 248-971-1
- SureCN574020
- 3-Amino-4-phenoxy-5-sulphamoylbenzoic acid
- Desbutylbumetanide
- 3-amino-4-phenoxy-5-sulphamyl benzoic acid
- A876737
- Bumetanide impurity B
- 3-Amino-5-(aminosulfonyl)-4-phenoxy-benzoic Acid
- NS00028461
- 5-Amino-3-aminosulfony-4-phenoxybenzoicacid
- FT-0665933
- 28328-54-3
- 9D69CZ7VGU
- UNII-9D69CZ7VGU
- GVQZPZSQRCXSJI-UHFFFAOYSA-N
- 3-Amino-4-phenoxy-5-sulfamoylbenoic acid
- 3-amino-4-phenoxy-5-sulfamoylbenzoic acid
- J-017046
- 3-sulphamoyl-4-phenoxy-5-aminobenzoic acid
- AKOS015967385
- FT-0665932
- DTXSID10182568
- BUMETANIDE IMPURITY B [EP IMPURITY]
- Benzoic acid, 3-amino-5-(aminosulfonyl)-4-phenoxy-
- 5-Amino-3-aminosulfony-4-phenoxybenzoic acid
- 3-amino-4-phenoxy-5-sulfamoylbenzoicacid
- SCHEMBL574020
- BUMETANIDE_met013
- DB-348061
-
- Inchi： 1S/C13H12N2O5S/c14-10-6-8(13(16)17)7-11(21(15,18)19)12(10)20-9-4-2-1-3-5-9/h1-7H,14H2,(H,16,17)(H2,15,18,19)
- InChI Key： GVQZPZSQRCXSJI-UHFFFAOYSA-N
- SMILES： S(C1C=C(C(=O)O)C=C(C=1OC1C=CC=CC=1)N)(N)(=O)=O
Computed Properties
- Exact Mass: 308.04676
- Monoisotopic Mass: 308.047
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 3
- Hydrogen Bond Acceptor Count: 7
- Heavy Atom Count: 21
- Rotatable Bond Count: 4
- Complexity: 469
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 141A^2
- XLogP3: 0.9
Experimental Properties
- Density: 1.512
- Boiling Point: 555.3°Cat760mmHg
- Flash Point: 289.6°C
- Refractive Index: 1.663
- PSA: 132.71
Desbutyl Bumetanide Security Information
- Hazardous Material transportation number：NONH for all modes of transport
Desbutyl Bumetanide Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| XI GE MA AO DE LI QI （ SHANG HAI ） MAO YI Co., Ltd. | Y0000310 |
28328-54-3 | ￥1544.34 | 2023-01-13 | ||||
| XI GE MA AO DE LI QI （ SHANG HAI ） MAO YI Co., Ltd. | 1078325-10MG |
Bumetanide Related Compound A |
28328-54-3 | 10mg |
￥10902.39 | 2023-09-09 | ||
| TRC | D288780-10mg |
Desbutyl Bumetanide |
28328-54-3 | 10mg |
$ 199.00 | 2023-09-08 | ||
| TRC | D288780-100mg |
Desbutyl Bumetanide |
28328-54-3 | 100mg |
$ 1579.00 | 2023-09-08 | ||
| Alichem | A019096697-100mg |
3-Amino-4-phenoxy-5-sulfamoylbenzoic acid |
28328-54-3 | 95% | 100mg |
$1142.40 | 2023-09-02 | |
| XI GE MA AO DE LI QI （ SHANG HAI ） MAO YI Co., Ltd. | 1078325-10MG |
28328-54-3 | 10MG |
￥15211.09 | 2023-01-06 | |||
| SHENG KE LU SI SHENG WU JI SHU | sc-211249-10 mg |
Desbutyl Bumetanide, |
28328-54-3 | 10mg |
￥2,106.00 | 2023-07-10 | ||
| SHENG KE LU SI SHENG WU JI SHU | sc-211249A-50 mg |
Desbutyl Bumetanide, |
28328-54-3 | 50mg |
￥10,830.00 | 2023-07-10 | ||
| SHENG KE LU SI SHENG WU JI SHU | sc-211249B-100 mg |
Desbutyl Bumetanide, |
28328-54-3 | 100MG |
￥21,059.00 | 2023-07-10 | ||
| SHENG KE LU SI SHENG WU JI SHU | sc-211249C-1 g |
Desbutyl Bumetanide, |
28328-54-3 | 1g |
￥120,336.00 | 2023-07-10 |
Desbutyl Bumetanide Related Literature
-
Jessica Fiori,Roberto Ballardini,Patrizia Hrelia,Vincenza Andrisano,Andrea Tarozzi,Vanni Cavrini Photochem. Photobiol. Sci. 2003 2 1011
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