• 1. Specific inhibitors in vitamin biosynthesis. Part 11. Syntheses of pterins with extended side chains at C-6
  Colin L. Gibson,Angus Lang,Kyuji Ohta,Colin J. Suckling J. Chem. Soc. Perkin Trans. 1 1999 163

• Solvents and Organic Chemicals Organic Compounds Organic acids and derivatives Carboxylic acids and derivatives Carboxylic acid derivatives Carboxylic acid amides

Comprehensive Overview of 2-Chloro-N-(hydroxymethyl)acetamide (CAS No. 2832-19-1): Properties, Applications, and Industry Insights

2-Chloro-N-(hydroxymethyl)acetamide, identified by its CAS number 2832-19-1, is a specialized organic compound with a unique molecular structure that combines chloro and hydroxymethyl functional groups. This chemical has garnered significant attention in pharmaceutical and agrochemical research due to its versatile reactivity. The compound's molecular formula C3H6ClNO2 and molecular weight 123.54 g/mol make it particularly useful in synthetic chemistry applications. Researchers frequently search for "2-Chloro-N-(hydroxymethyl)acetamide synthesis" or "2832-19-1 solubility data," reflecting the growing interest in its practical applications.

In recent years, the demand for high-purity 2-Chloro-N-(hydroxymethyl)acetamide has increased substantially, particularly in the development of novel pharmaceutical intermediates. The compound's hydroxymethyl group offers excellent potential for further derivatization, making it valuable in drug discovery programs. Industry professionals often inquire about "2-Chloro-N-(hydroxymethyl)acetamide stability" and "storage conditions for CAS 2832-19-1," highlighting the need for proper handling information. The compound typically appears as a white to off-white crystalline powder with a melting point range of 85-90°C, characteristics that are crucial for formulation scientists.

The reactivity of 2-Chloro-N-(hydroxymethyl)acetamide has made it particularly interesting in green chemistry initiatives. With growing environmental concerns, researchers are exploring "eco-friendly synthesis of 2832-19-1" and "biodegradable derivatives of chloroacetamides." The compound's chloroacetamide moiety allows for selective nucleophilic substitutions, while the hydroxymethyl functionality enables condensation reactions, providing multiple pathways for structural modifications. These properties align well with current trends toward sustainable chemical production.

Analytical characterization of CAS 2832-19-1 typically involves advanced techniques such as HPLC purity analysis, NMR spectroscopy, and mass spectrometry. Quality control laboratories frequently search for "2-Chloro-N-(hydroxymethyl)acetamide HPLC method" or "2832-19-1 spectroscopic data," underscoring the importance of reliable analytical protocols. The compound shows characteristic IR absorption bands at 3300 cm?1 (O-H stretch) and 1650 cm?1 (C=O stretch), which serve as important identification markers.

From a commercial perspective, 2-Chloro-N-(hydroxymethyl)acetamide has seen steady market growth, with suppliers offering various technical grade and research grade specifications. Procurement specialists often look for "bulk suppliers of 2832-19-1" or "2-Chloro-N-(hydroxymethyl)acetamide price trends," indicating its economic significance. The global market for this chemical is expected to expand further as its applications in specialty chemicals continue to diversify, particularly in regions with strong pharmaceutical manufacturing sectors.

Safety considerations for handling 2-Chloro-N-(hydroxymethyl)acetamide remain a top priority, with proper personal protective equipment (PPE) being essential during laboratory operations. While not classified as hazardous under standard regulations, appropriate ventilation controls and chemical handling protocols should always be followed. This aligns with industry searches for "safe handling of CAS 2832-19-1" and "2-Chloro-N-(hydroxymethyl)acetamide material safety data," reflecting the chemical community's commitment to responsible research practices.

Future research directions for 2832-19-1 may explore its potential in polymer chemistry and material science applications. The compound's bifunctional nature suggests possible utility in creating cross-linked polymers or specialty coatings. Academic researchers are increasingly investigating "2-Chloro-N-(hydroxymethyl)acetamide polymerization" and "2832-19-1 in smart materials," pointing to emerging applications beyond its traditional uses. These developments could open new avenues for this versatile chemical intermediate in advanced technological applications.

• 3622-77-3(Acetamide, 2-chloro-N-(methoxymethyl)-)
• 34891-76-4(Acetamide,2,2,2-trichloro-N-(hydroxymethyl)-)
• 96-30-0(2-Chloro-N-methylacetamide)
• 3622-80-8(Acetamide, 2-chloro-N,N-bis(hydroxymethyl)-)
• 1555-91-5(Acetamide, 2,2-dichloro-N-(hydroxymethyl)-)
• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)