• 1. An investigation of surface properties, local elastic modulus and interaction with simulated pulmonary surfactant of surface modified inhalable voriconazole dry powders using atomic force microscopy
  Michael Kappl,Paul M. Young,Daniela Traini,Sanyog Jain RSC Adv., 2016,6, 25789-25798
• 2. An analyte-triggered artificial peroxidase system based on dimanganese complex for a versatile enzyme assay?
  Suji Lee,Min Su Han Chem. Commun., 2021,57, 9450-9453
• 3. An approach for correlating the structural and electrical properties of Zr4+-modified SrBi4Ti4O15/SBT ceramic
  Priyambada Nayak,Tanmaya Badapanda,Anil Kumar Singh,Simanchalo Panigrahi RSC Adv., 2017,7, 16319-16331
• 4. An atom efficient route to N-aryl and N-alkyl pyrrolines by transition metal catalysis?
  Supaporn Sawadjoon,Joseph S. M. Samec Org. Biomol. Chem., 2011,9, 2548-2554
• 5. An aptasensor for detection of potassium ions based on RecJf exonuclease mediated signal amplification
  Bidou Wang,Xifeng Chen Analyst, 2014,139, 5695-5699

6-Ethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-sulfonyl Chloride: A Comprehensive Overview

The compound 6-Ethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-sulfonyl chloride, identified by the CAS number 2763909-13-1, is a significant molecule in the field of organic chemistry. This compound belongs to the class of sulfonyl chlorides and is characterized by its unique structure and versatile applications. The molecule consists of a pyrimidine ring system with substituents that confer specific chemical reactivity and functional properties.

The synthesis of 6-Ethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-sulfonyl chloride involves a series of well-defined chemical reactions. The starting material typically undergoes sulfonation followed by chlorination to yield the final product. This process ensures the formation of a stable sulfonyl chloride group attached to the pyrimidine framework. The ethyl substituent at position 6 plays a crucial role in modulating the physical and chemical properties of the compound.

In recent years, there has been growing interest in the application of 6-Ethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-based compounds in various fields. One notable area is their use as intermediates in drug discovery. The sulfonyl chloride group is highly reactive and can be employed in nucleophilic substitution reactions to form diverse derivatives with potential pharmacological activity. For instance, researchers have explored its role in developing inhibitors for specific enzyme targets.

The structural versatility of this compound also makes it an attractive candidate for materials science applications. The pyrimidine ring system provides a rigid framework that can be functionalized to create advanced materials with tailored properties. Recent studies have highlighted its potential as a building block for constructing coordination polymers and metal organic frameworks (MOFs), which are widely used in catalysis and gas storage.

From an environmental perspective, understanding the degradation pathways of CAS No 2763909-13-1 is critical for assessing its ecological impact. Research has shown that under certain conditions, the sulfonyl chloride group undergoes hydrolysis to form corresponding sulfonic acids. This transformation not only affects the compound's stability but also influences its bioavailability and toxicity profiles.

In summary, 6-Ethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-based compounds represent a promising class of molecules with diverse applications across multiple disciplines. Their unique chemical structure and reactivity continue to drive innovative research directions in drug development and materials science. As our understanding of their properties deepens through ongoing studies and technological advancements

• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
• 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
• 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)
• 2034271-14-0(2-(1H-indol-3-yl)-N-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}acetamide)