Cas no 27297-39-8 (Sodium lactobionate)

Sodium lactobionate is a sodium salt of lactobionic acid, derived from the oxidation of lactose. It is a white to off-white crystalline powder with high solubility in water. This compound is valued for its chelating properties, making it useful in stabilizing metal ions in pharmaceutical and cosmetic formulations. Its non-toxic and biocompatible nature allows for applications in medical fields, including as an excipient in injectable drugs and organ preservation solutions. Sodium lactobionate also exhibits moisturizing and humectant characteristics, enhancing its utility in dermatological and personal care products. Its stability and mildness further contribute to its suitability for sensitive formulations.
Sodium lactobionate structure
Sodium lactobionate structure
Product Name:Sodium lactobionate
CAS No:27297-39-8
MF:C12H21NaO12
MW:380.277716398239
MDL:MFCD06658158
CID:53116
PubChem ID:53486225
Update Time:2025-06-14

Sodium lactobionate Chemical and Physical Properties

Names and Identifiers

    • Sodium Lactobionate
    • Lactobionic acid sodium
    • lactobionic acid sodium salt
    • SodiuM LaCLobionate
    • BCP22132
    • CID 134694960
    • 4-O-β-D-Galactopyranosyl-D-gluconic acid sodium salt
    • Lactobionic acid sodium salt monohydrate
    • D-Gluconic acid, 4-O-b-D-galactopyranosyl-, sodiuM salt(1:1)
    • 4-O-BETA-GALACTOPYRANOSYL-D-GLUCONIC ACID MONOSODIUM SALT
    • CS-0208898
    • AC-8302
    • AS-14862
    • AKOS015924797
    • MFCD06658158
    • F71416
    • Sodiumlactobionate
    • sodium (2R,3R,4R,5R)-2,3,5,6-tetrahydroxy-4-((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)hexanoate
    • 27297-39-8
    • Sodium (2R,3R,4R,5R)-2,3,5,6-tetrahydroxy-4-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexanoate
    • Sodium (2R,3R,4R,5R)-2,3,5,6-tetrahydroxy-4-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-
    • Sodium lactobionate, 98%
    • D-Gluconic acid, 4-O-b-D-galactopyranosyl-, monosodium salt
    • Sodium lactobionate
    • MDL: MFCD06658158
    • Inchi: 1S/C12H22O12.Na/c13-1-3(15)10(7(18)8(19)11(21)22)24-12-9(20)6(17)5(16)4(2-14)23-12;/h3-10,12-20H,1-2H2,(H,21,22);/q;+1/p-1/t3-,4-,5+,6+,7-,8-,9-,10-,12+;/m1./s1
    • InChI Key: AQKFVNLHZYOMKQ-WWNCWODVSA-M
    • SMILES: [Na+].O1[C@H](CO)[C@@H]([C@@H]([C@H]([C@@H]1O[C@H]([C@@H](CO)O)[C@@H]([C@H](C(=O)[O-])O)O)O)O)O

Computed Properties

  • Exact Mass: 380.09300
  • Monoisotopic Mass: 380.093
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 8
  • Hydrogen Bond Acceptor Count: 12
  • Heavy Atom Count: 25
  • Rotatable Bond Count: 8
  • Complexity: 412
  • Covalently-Bonded Unit Count: 2
  • Defined Atom Stereocenter Count: 9
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 220

Experimental Properties

  • Color/Form: No data available
  • Melting Point: 160 - 170°C
  • Boiling Point: No data available
  • Flash Point: No data available
  • PSA: 220.43000
  • LogP: -7.00360
  • Vapor Pressure: No data available

Sodium lactobionate Pricemore >>

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Sodium lactobionate Production Method

Sodium lactobionate Suppliers

Tiancheng Chemical (Jiangsu) Co., Ltd
Gold Member
Audited Supplier Audited Supplier
(CAS:27297-39-8)Sodium lactobionate
Order Number:LE620
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 11:39
Price ($):discuss personally
NewCan Biotech Limited
Gold Member
Audited Supplier Audited Supplier
(CAS:27297-39-8)Sodium lactobionate
Order Number:NC11954
Stock Status:
Quantity:10g
Purity:97%
Pricing Information Last Updated:Friday, 18 July 2025 16:07
Price ($):Price inquiry

Sodium lactobionate Related Literature

Additional information on Sodium lactobionate

Recent Advances in Sodium Lactobionate (27297-39-8) Research: Applications and Innovations in Chemical Biomedicine

Sodium lactobionate (CAS: 27297-39-8), a derivative of lactose, has garnered significant attention in the field of chemical biomedicine due to its versatile applications in drug formulation, organ preservation, and as a biocompatible excipient. Recent studies have explored its role in enhancing the stability and efficacy of therapeutic agents, particularly in parenteral formulations. This research brief synthesizes the latest findings on Sodium lactobionate, highlighting its chemical properties, mechanisms of action, and emerging applications in biomedicine.

One of the most notable advancements in Sodium lactobionate research is its use as a cryoprotectant and organ preservation agent. A 2023 study published in the Journal of Biomedical Materials Research demonstrated that Sodium lactobionate significantly reduces ischemic injury in transplanted organs by stabilizing cell membranes and mitigating oxidative stress. The study utilized a rat liver transplantation model, where organs preserved with Sodium lactobionate exhibited improved viability and reduced post-transplant inflammation compared to traditional preservation solutions. These findings underscore its potential to revolutionize organ transplantation protocols.

In drug delivery systems, Sodium lactobionate has been investigated for its ability to enhance the solubility and bioavailability of poorly water-soluble drugs. A recent Pharmaceutical Research article (2024) reported the development of a novel nanoparticle-based delivery system incorporating Sodium lactobionate as a stabilizer. The system demonstrated a 40% increase in drug loading capacity and sustained release kinetics, making it particularly suitable for anticancer therapies. The researchers attributed these improvements to the compound's amphiphilic nature, which facilitates interactions with both hydrophobic drugs and aqueous environments.

Furthermore, Sodium lactobionate has shown promise in the field of diagnostic imaging. A 2024 study in Contrast Media & Molecular Imaging revealed its utility as a contrast agent enhancer in magnetic resonance imaging (MRI). By chelating gadolinium ions, Sodium lactobionate improved the contrast-to-noise ratio by 25% while reducing the risk of nephrogenic systemic fibrosis, a common side effect of gadolinium-based contrast agents. This innovation could lead to safer and more effective imaging techniques for patients with renal impairment.

Despite these advancements, challenges remain in the large-scale production and standardization of Sodium lactobionate for clinical applications. Recent research published in Biotechnology Progress (2023) has focused on optimizing fermentation processes to increase yield and purity. The study identified specific strain engineering strategies that improved lactobionic acid production by 30%, with subsequent conversion to Sodium lactobionate achieving pharmaceutical-grade purity. These developments are critical for meeting the growing demand in biomedical applications.

Looking ahead, the unique properties of Sodium lactobionate (27297-39-8) position it as a multifunctional agent in chemical biomedicine. Ongoing research is exploring its potential in wound healing, antimicrobial coatings, and as a component of bioinks for 3D bioprinting. As these applications mature, Sodium lactobionate is expected to play an increasingly important role in advancing therapeutic and diagnostic technologies, offering solutions to some of biomedicine's most pressing challenges.

Recommended suppliers
Tiancheng Chemical (Jiangsu) Co., Ltd
(CAS:27297-39-8)Sodium lactobionate
LE620
Purity:99%
Quantity:25KG,200KG,1000KG
Price ($):Inquiry
Email
NewCan Biotech Limited
(CAS:27297-39-8)Sodium lactobionate
NC11954
Purity:97%
Quantity:10g
Price ($):Inquiry
Email