Cas no 27021-04-1 (4-Hydroxy-2,5-dimethylbenzoic acid)

4-Hydroxy-2,5-dimethylbenzoic acid structure
27021-04-1 structure
Product Name:4-Hydroxy-2,5-dimethylbenzoic acid
CAS No:27021-04-1
MF:C9H10O3
MW:166.173902988434
MDL:MFCD09999327
CID:1015708
Update Time:2025-10-29

4-Hydroxy-2,5-dimethylbenzoic acid Chemical and Physical Properties

Names and Identifiers

    • 4-Hydroxy-2,5-dimethylbenzoic acid
    • 4-hydroxy-2,5-dimethyl-benzoic acid
    • MDL: MFCD09999327
    • Inchi: 1S/C9H10O3/c1-5-4-8(10)6(2)3-7(5)9(11)12/h3-4,10H,1-2H3,(H,11,12)
    • InChI Key: NNZOKYRQPZZEAR-UHFFFAOYSA-N
    • SMILES: OC1=CC(C)=C(C(=O)O)C=C1C

Computed Properties

  • Exact Mass: 166.06300
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 12
  • Rotatable Bond Count: 1

Experimental Properties

  • PSA: 57.53000
  • LogP: 1.70720

4-Hydroxy-2,5-dimethylbenzoic acid Customs Data

  • HS CODE:2918290000
  • Customs Data:

    China Customs Code:

    2918290000

    Overview:

    2918290000 Other carboxylic acids and anhydrides containing phenolic groups but not other oxy groups\Acyl halide\Peroxides and peroxyacids and their derivatives.Regulatory conditions:AB(Customs clearance form for Inbound Goods,Customs clearance form for outbound goods).VAT:17.0%.Tax refund rate:9.0%.MFN tariff:6.5%.general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to

    Regulatory conditions:

    A.Customs clearance form for Inbound Goods
    B.Customs clearance form for outbound goods

    Inspection and quarantine category:

    R.Sanitary supervision and inspection of imported food
    S.Sanitary supervision and inspection of exported food

    Summary:

    HS: 2918290000 other carboxylic acids with phenol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) VAT:17.0% MFN tariff:6.5% General tariff:30.0%

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4-Hydroxy-2,5-dimethylbenzoic acid Production Method

Additional information on 4-Hydroxy-2,5-dimethylbenzoic acid

4-Hydroxy-2,5-dimethylbenzoic Acid: Properties, Applications, and Market Insights

4-Hydroxy-2,5-dimethylbenzoic acid (CAS No. 27021-04-1) is a versatile organic compound with a wide range of applications in pharmaceuticals, cosmetics, and specialty chemicals. This hydroxybenzoic acid derivative is known for its unique chemical structure, which includes both hydroxyl and carboxyl functional groups, making it a valuable intermediate in synthetic chemistry. Researchers and industry professionals often search for 4-Hydroxy-2,5-dimethylbenzoic acid uses, synthesis methods, and safety data, reflecting its growing importance in various sectors.

The compound is characterized by its white to off-white crystalline powder appearance and moderate solubility in polar solvents like ethanol and water. Its molecular formula, C9H10O3, and molecular weight of 166.17 g/mol make it an interesting subject for organic chemistry research. Recent studies have focused on its potential as a building block for drug development, particularly in creating anti-inflammatory and antimicrobial agents. The increasing demand for specialty chemicals in the pharmaceutical industry has driven more attention to this compound in 2023-2024.

In the pharmaceutical sector, 4-Hydroxy-2,5-dimethylbenzoic acid serves as a key intermediate for synthesizing various active pharmaceutical ingredients (APIs). Its structural similarity to salicylic acid makes it particularly valuable for developing new dermatological treatments, a hot topic in cosmetic and medical research. Many formulators search for 4-Hydroxy-2,5-dimethylbenzoic acid in skincare applications due to its potential antioxidant properties and mild exfoliating effects.

The compound's applications extend to the food industry, where it's investigated as a potential food preservative alternative. With consumers increasingly concerned about clean-label ingredients, researchers are examining its efficacy compared to traditional preservatives like benzoic acid. This aligns with current trends in natural preservation solutions, a frequently searched topic in food science communities.

From a synthetic chemistry perspective, 4-Hydroxy-2,5-dimethylbenzoic acid offers interesting possibilities for green chemistry applications. Recent patents have disclosed methods for its production using more sustainable catalysts and reduced energy consumption, addressing the growing demand for eco-friendly chemical synthesis. These developments respond to frequent searches about sustainable chemical production methods in academic and industrial circles.

The global market for 4-Hydroxy-2,5-dimethylbenzoic acid has shown steady growth, particularly in Asia-Pacific regions where pharmaceutical and cosmetic industries are expanding rapidly. Market analysts note increased interest in high-purity grades of this compound, especially for research and development purposes. Quality specifications typically include parameters like purity (≥98%), melting point (210-215°C), and residual solvent content, which are common search terms among procurement specialists.

Storage and handling of 4-Hydroxy-2,5-dimethylbenzoic acid require standard laboratory precautions. The compound should be kept in tightly closed containers, protected from light and moisture at room temperature. While not classified as hazardous under normal handling conditions, proper laboratory safety protocols should always be followed, a topic frequently searched by new researchers entering the field.

Analytical methods for characterizing 4-Hydroxy-2,5-dimethylbenzoic acid typically include HPLC, GC-MS, and NMR spectroscopy. These techniques help verify purity and identify potential impurities, crucial information for researchers searching for analytical methods for benzoic acid derivatives. Recent advancements in analytical chemistry have improved detection limits for related compounds, supporting quality control in manufacturing processes.

Future research directions for 4-Hydroxy-2,5-dimethylbenzoic acid may explore its potential in biodegradable materials and renewable energy applications. Some preliminary studies suggest possible uses in organic electronics and polymer chemistry, aligning with current interests in sustainable material science. These emerging applications could drive additional demand and research interest in coming years.

For researchers considering working with 4-Hydroxy-2,5-dimethylbenzoic acid, it's important to consult recent literature and patent databases to stay updated on the latest developments. The compound's versatility ensures it remains relevant across multiple disciplines, from medicinal chemistry to material science, making it a worthwhile subject for both academic and industrial investigation.

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