Cas no 26934-87-2 (HT-2 Toxin)

HT-2 Toxin is a type A trichothecene mycotoxin produced primarily by Fusarium species, notably F. sporotrichioides and F. poae. It is a secondary metabolite known for its potent cytotoxic effects, inhibiting protein synthesis by binding to ribosomal subunits. HT-2 Toxin is structurally similar to T-2 Toxin but differs in its hydroxylation pattern, influencing its toxicity and metabolic pathways. It is commonly studied in food safety, toxicology, and agricultural research due to its presence in contaminated cereals and its implications for human and animal health. Analytical standards of HT-2 Toxin are used for accurate detection and quantification in regulatory and research applications.
HT-2 Toxin structure
HT-2 Toxin structure
Product Name:HT-2 Toxin
CAS No:26934-87-2
MF:C22H32O8
MW:424.484687805176
CID:254966
PubChem ID:10093830
Update Time:2025-11-07

HT-2 Toxin Chemical and Physical Properties

Names and Identifiers

    • Trichothec-9-ene-3,4,8,15-tetrol,12,13-epoxy-, 15-acetate 8-(3-methylbutanoate), (3a,4b,8a)-
    • HT-2 Toxin
    • 15-Acetoxy-3α,4β-dihydroxy-8α-(3-methylbutyryloxy)-12,13-epoxytrichothec-9-ene
    • HT-2
    • ht-2toxin solution
    • Mycotoxin HT 2
    • Pentanoic acid anion
    • T-2,Toxin analog
    • Toxin HT 2
    • valerate
    • (3alpha,4beta,8alpha)-12,13-Epoxytrichothec-9-ene-3,4,8,15-tetrol 15-acetate 8-(3-methylbutanoate)
    • 1ST7237
    • CS-0099767
    • Diisobutyl Phosphite-d14
    • Trichothec-9-ene-3alpha,4beta,8alpha,15-tetrol, 12,13-epoxy-, 15-acetate 8-isovalerate
    • Q27896911
    • NC6C26RM46
    • Trichothec-9-ene-3,4,8,15-tetrol, 12,13-epoxy-, 15 acetate 8-(3-methylbutanoate), (3alpha,4abeta,8alpha)-
    • 12,13-Epoxytrichothec-9-ene-3-alpha,4-beta,8-alpha,15-tetrol 15-acetate 8-isovalerate
    • 12,13-Epoxytrichothec-9-ene-3,4,8,15-tetrol 15-acetate 8-(3-methylbutanoate), (3alpha,4beta,8alpha)-
    • NCGC00380750-01
    • 26934-87-2
    • HT 2 Toxin
    • 15-(acetyloxy)-3alpha,4beta-dihydroxy-12,13-epoxytrichothec-9-en-8alpha-yl 3-methylbutanoate
    • DTXSID60891810
    • 1ST7237-100A
    • 3,4-DIHYDROXY-15-ACETOXY-8-(3-METHYLBUTYRYLOXY)-12,13-EPOXY-.DELTA.9-TRICHOTHECENE
    • NSC-278571
    • 3,4-dihydroxy-15-acetoxy-8-(3-methylbutyryloxy)-12,13-epoxy-delta9-trichothecene
    • AS-78686
    • [(1S,2R,4S,7R,9R,10R,11S,12S)-2-(acetyloxymethyl)-10,11-dihydroxy-1,5-dimethylspiro[8-oxatricyclo[7.2.1.02,7]dodec-5-ene-12,2'-oxirane]-4-yl] 3-methylbutanoate
    • CHEMBL440357
    • Trichothec-9-ene-3,4,8,15-tetrol, 12,13-epoxy-, 15-acetate 8-(3-methylbutanoate), (3alpha,4beta,8alpha)-
    • Trichothec-9-ene-3-alpha,4-beta,8-alpha,15-tetrol, 12,13-epoxy-, 15-acetate, 8-isovalerate
    • BH162733
    • CHEBI:138861
    • mycotoxin HT-2
    • HT-2 Toxin in Acetonitrile, 100ug/mL
    • 15-Acetoxy-3,4-dihydroxy-8-(3-methylbutyryloxy)-12,13-epoxy delta9-trichothecene
    • NSC 278571
    • UNII-NC6C26RM46
    • HT 2
    • HY-N6729
    • Trichothec-9-ene-3.alpha.,8.alpha.,15-tetrol, 12,13-epoxy-, 15-acetate 8-isovalerate
    • NSC278571
    • TOXIN HT2
    • CHEMBL1996430
    • Trichothec-9-ene-3,8,15-tetrol, 12,13-epoxy-, 15 acetate 8-(3-methylbutanoate), (3.alpha.,4a.beta.,8.alpha.)-
    • NS00000153
    • Trichothec-9-ene-3.alpha.,8.alpha.,15-tetrol, 12,13-epoxy-, 15-acetate, 8-isovalerate
    • NCI60_002267
    • Trichothen-9-ene-3,8,15-tetrol, 12,13-epoxy-, 15-acetate 8-(3-methylbutanoate)
    • C19952
    • Trichothec-9-ene-3,8,15-tetrol, 12,13-epoxy-, 15-acetate 8-(3-methylbutanoate), (3.alpha.,4.beta.,8.alpha.)-
    • HT-2 Toxin 100 microg/mL in Acetonitrile
    • ?HT-2 TOXIN
    • 2'-[(acetyloxy)methyl]-10',11'-dihydroxy-1',5'-dimethyl-8'-oxaspiro[oxirane-2,12'-tricyclo[7.2.1.02,7]dodecan]-5'-en-4'-yl 3-methylbutanoate
    • G16868
    • Trichothec-9-ene-3alpha,4beta,8alpha,15-tetrol, 12,13-epoxy-, 15-acetate 8-isovalerate (8CI)
    • [(1S,2R,4S,7R,9R,10R,11S,12R)-2-(acetyloxymethyl)-10,11-dihydroxy-1,5-dimethylspiro[8-oxatricyclo[7.2.1.02,7]dodec-5-ene-12,2'-oxirane]-4-yl] 3-methylbutanoate
    • Trichothec-9-ene-3,4,8,15-tetrol, 12,13-epoxy-, 15-acetate 8-(3-methylbutanoate), (3.alpha.,4.beta.,8.alpha.)-
    • PNKLMTPXERFKEN-MLXHEQMXSA-N
    • 12,13-Epoxytrichothec-9-ene-3-.alpha.,4-.beta.,8-.alpha.,15-tetrol 15-acetate 8-isovalerate
    • Trichothec-9-ene-3,4,8,15-tetrol, 12,13-epoxy-, 15 acetate 8-(3-methylbutanoate), (3alpha,4abeta,8alpha)-(9CI)
    • ((1S,2R,4S,7R,9R,10R,11S,12R)-2-(acetyloxymethyl)-10,11-dihydroxy-1,5-dimethylspiro(8-oxatricyclo(7.2.1.02,7)dodec-5-ene-12,2'-oxirane)-4-yl) 3-methylbutanoate
    • Trichothec-9-ene-3,4,8,15-tetrol, 12,13-epoxy-, 15-acetate 8-(3-methylbutanoate), (3alpha,4beta,8alpha)-(9CI)
    • 2'-((acetyloxy)methyl)-10',11'-dihydroxy-1',5'-dimethyl-8'-oxaspiro(oxirane-2,12'-tricyclo(7.2.1.02,7)dodecan)-5'-en-4'-yl 3-methylbutanoate
    • (1'R,2R,2'S,4'R,7'S,9'S,10'R,11'S)-2'-[(acetyloxy)methyl]-10',11'-dihydroxy-1',5'-dimethyl-8'-oxaspiro[oxirane-2,12'-tricyclo[7.2.1.0{2,7}]dodecan]-5'-en-4'-yl 3-methylbutanoate
    • 15-acetoxy-3,4-dihydroxy-8-(3-methylbutyryloxy)-12,13-epoxy delta 9-trichothecene
    • ((1S,2R,4S,7R,9R,10R,11S,12S)-2-(acetyloxymethyl)-10,11-dihydroxy-1,5-dimethylspiro(8-oxatricyclo(7.2.1.02,7)dodec-5-ene-12,2'-oxirane)-4-yl) 3-methylbutanoate
    • (1'R,2R,2'S,4'R,7'S,9'S,10'R,11'S)-2'-((acetyloxy)methyl)-10',11'-dihydroxy-1',5'-dimethyl-8'-oxaspiro(oxirane-2,12'-tricyclo(7.2.1.0(2,7))dodecan)-5'-en-4'-yl 3-methylbutanoate
    • DTXCID401031048
    • Trichothec-9-ene-3.alpha.,4.beta.,8.alpha.,15-tetrol, 12,13-epoxy-, 15-acetate 8-isovalerate
    • MDL： MFCD00056784
    • Inchi： 1S/C22H32O8/c1-11(2)6-16(24)29-14-8-21(9-27-13(4)23)15(7-12(14)3)30-19-17(25)18(26)20(21,5)22(19)10-28-22/h7,11,14-15,17-19,25-26H,6,8-10H2,1-5H3/t14-,15+,17+,18+,19+,20+,21+,22-/m0/s1
    • InChI Key： PNKLMTPXERFKEN-MLXHEQMXSA-N
    • SMILES： O1C[C@]21[C@H]1[C@@H]([C@H]([C@]2(C)[C@@]2(COC(C)=O)C[C@@H](C(C)=C[C@H]2O1)OC(CC(C)C)=O)O)O

Computed Properties

  • Exact Mass: 424.21000
  • Monoisotopic Mass: 424.21
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 8
  • Heavy Atom Count: 30
  • Rotatable Bond Count: 7
  • Complexity: 777
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 8
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 115A^2
  • XLogP3: 0.4

Experimental Properties

  • Color/Form: Solid
  • Density: 1.30±0.1 g/cm3 (20 oC 760 Torr),
  • Boiling Point: 537.1±50.0 °C at 760 mmHg
  • Flash Point: 2?°C
  • Refractive Index: 1.562
  • Solubility: Slightly soluble (1.1 g/l) (25 o C),
  • PSA: 114.82000
  • LogP: 1.12190
  • Vapor Pressure: 0.0±3.2 mmHg at 25°C

HT-2 Toxin Security Information

HT-2 Toxin Pricemore >>

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HT-2 Toxin Related Literature

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Additional information on HT-2 Toxin

HT-2 Toxin: A Comprehensive Overview

The HT-2 Toxin, also known by its CAS number 26934-87-2, is a mycotoxin produced by certain Fusarium species. This compound has garnered significant attention in the fields of food safety, agriculture, and toxicology due to its potential health risks and environmental impacts. Recent studies have shed light on its mechanisms of action, detection methods, and mitigation strategies, making it a critical area of research.

HT-2 Toxin is classified as a type B trichothecene mycotoxin, which is known for its potent cytotoxic effects. It is commonly found in contaminated grains, particularly wheat and barley, which poses a significant threat to both human and animal health. The toxin's ability to persist in the environment and its resistance to thermal degradation further complicate efforts to control its spread.

Recent advancements in analytical techniques have improved the detection of HT-2 Toxin. High-performance liquid chromatography (HPLC) coupled with mass spectrometry (MS) has become the gold standard for quantifying this compound in complex matrices. Additionally, the development of immunoassays has enabled rapid and cost-effective screening methods, which are crucial for large-scale food safety monitoring programs.

The biosynthesis of HT-2 Toxin involves a complex network of genes and enzymes. Researchers have identified key regulatory genes such as Fusarium transcription factors that control toxin production. Understanding these pathways has opened new avenues for genetic engineering approaches to develop Fusarium-resistant crop varieties.

In terms of health effects, HT-2 Toxin has been linked to various adverse outcomes, including immunosuppression, gastrointestinal distress, and reproductive issues. Emerging studies suggest that chronic exposure may also contribute to long-term health complications, underscoring the need for stringent regulatory limits and effective detoxification strategies.

The application of nanotechnology in detoxification has shown promise in reducing the levels of HT-2 Toxin. Nanoparticles such as activated carbon and clay minerals have demonstrated high adsorption capacities for this compound, offering a potential solution for contaminated food products.

In conclusion, HT-2 Toxin, with its CAS number 26934-87-2, remains a critical focus in mycotoxin research. Its impact on food safety and public health necessitates continued investment in research and development to mitigate its risks. As new technologies emerge, the ability to detect, prevent, and neutralize this toxin will play a pivotal role in ensuring global food security.

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Amadis Chemical Company Limited
(CAS:26934-87-2)HT-2 Toxin
A1024451
Purity:99%/99%
Quantity:5mg/1mg
Price ($):2194.0/518.0
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Suzhou Senfeida Chemical Co., Ltd
(CAS:26934-87-2)HT-2 TOXIN
sfd21495
Purity:99%
Quantity:200kg
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