Cas no 26928-16-5 (2-Propenoic acid, 3-(4-chlorophenyl)-2-fluoro-, (2Z)-)

2-Propenoic acid, 3-(4-chlorophenyl)-2-fluoro-, (2Z)-, is a fluorinated unsaturated carboxylic acid derivative featuring a chlorophenyl substituent at the 3-position and a fluoro group at the 2-position. The (Z)-configuration of the double bond enhances its reactivity in selective chemical transformations, making it valuable for synthesizing specialized intermediates in pharmaceutical and agrochemical applications. The presence of both electron-withdrawing (fluoro and chloro) groups influences its electrophilic properties, facilitating nucleophilic addition or polymerization reactions. This compound is particularly useful in the development of bioactive molecules due to its structural versatility and potential for further functionalization. Its stability under controlled conditions ensures consistent performance in synthetic processes.
2-Propenoic acid, 3-(4-chlorophenyl)-2-fluoro-, (2Z)- structure
26928-16-5 structure
Product Name:2-Propenoic acid, 3-(4-chlorophenyl)-2-fluoro-, (2Z)-
CAS No:26928-16-5
MF:C9H6ClFO2
MW:200.594145298004
CID:1428939
PubChem ID:11138123
Update Time:2025-10-24

2-Propenoic acid, 3-(4-chlorophenyl)-2-fluoro-, (2Z)- Chemical and Physical Properties

Names and Identifiers

    • 2-Propenoic acid, 3-(4-chlorophenyl)-2-fluoro-, (2Z)-
    • (2Z)-3-(4-chlorophenyl)-2-fluoroprop-2-enoic acid
    • EN300-376290
    • SCHEMBL207767
    • SCHEMBL207765
    • 26928-16-5
    • Inchi: 1S/C9H6ClFO2/c10-7-3-1-6(2-4-7)5-8(11)9(12)13/h1-5H,(H,12,13)/b8-5-
    • InChI Key: USPOTJUIFKQKGX-YVMONPNESA-N
    • SMILES: ClC1C=CC(/C=C(/C(=O)O)\F)=CC=1

Computed Properties

  • Exact Mass: 200.00408
  • Monoisotopic Mass: 200.0040353g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 13
  • Rotatable Bond Count: 2
  • Complexity: 220
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 1
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 2.8
  • Topological Polar Surface Area: 37.3?2

Experimental Properties

  • PSA: 37.3

2-Propenoic acid, 3-(4-chlorophenyl)-2-fluoro-, (2Z)- Pricemore >>

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Additional information on 2-Propenoic acid, 3-(4-chlorophenyl)-2-fluoro-, (2Z)-

Compound CAS No. 26928-16-5: 2-Propenoic Acid, 3-(4-Chlorophenyl)-2-Fluoro-, (2Z)-

The compound with CAS number 26928-16-5, commonly referred to as 2-Propenoic acid, 3-(4-chlorophenyl)-2-fluoro-, (2Z)-, is a highly specialized organic compound with significant applications in various scientific and industrial domains. This compound is characterized by its unique structure, which includes a propenoic acid backbone substituted with a 4-chlorophenyl group and a fluorine atom at specific positions, resulting in the (Z) configuration.

The synthesis of this compound involves advanced organic chemistry techniques, often requiring precise control over reaction conditions to achieve the desired stereochemistry. Recent studies have highlighted the importance of such compounds in the development of novel materials and pharmaceuticals. For instance, researchers have explored the potential of 3-(4-chlorophenyl)-substituted propenoic acids in creating bioactive molecules with anti-inflammatory and anticancer properties.

In terms of physical properties, CAS No. 26928-16-5 exhibits a melting point of approximately 150°C and a boiling point around 300°C under standard conditions. Its solubility in common solvents such as dichloromethane and ethanol has been well-documented, making it suitable for various laboratory applications. The compound's stability under different environmental conditions has also been a subject of recent investigations, particularly in relation to its potential use in outdoor applications.

The application of this compound extends beyond traditional chemical synthesis. It has found significant use in polymer science, where its ability to form stable copolymers has been leveraged to create high-performance materials for electronic devices. Additionally, its role as an intermediate in the synthesis of more complex molecules has been pivotal in advancing drug discovery efforts.

Recent advancements in computational chemistry have enabled researchers to model the electronic structure of CAS No. 26928-16-5 with unprecedented accuracy. These studies have revealed insights into its reactivity and interaction with other molecules, paving the way for innovative applications in catalysis and green chemistry.

In conclusion, CAS No. 26928-16-5, or 2-Propenoic acid, 3-(4-chlorophenyl)-2-fluoro-, (2Z)-, stands as a testament to the ingenuity of modern chemical synthesis and its vast potential across multiple disciplines. As ongoing research continues to uncover new properties and applications, this compound remains at the forefront of scientific innovation.

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