Cas no 26820-65-5 (2-Ethylamino-3-nitropyridine)

2-Ethylamino-3-nitropyridine is a nitro-substituted pyridine derivative with a molecular formula of C7H9N3O2. This compound features both an ethylamino group and a nitro group attached to the pyridine ring, imparting unique reactivity for applications in pharmaceutical intermediates and agrochemical synthesis. Its structure allows for further functionalization, making it a versatile building block in heterocyclic chemistry. The nitro group enhances electrophilic properties, facilitating nucleophilic substitution reactions, while the ethylamino moiety contributes to solubility and binding interactions. Suitable for research and industrial use, it is characterized by high purity and stability under standard conditions. Proper handling and storage are recommended due to its potential sensitivity to light and moisture.
2-Ethylamino-3-nitropyridine structure
2-Ethylamino-3-nitropyridine structure
Product Name:2-Ethylamino-3-nitropyridine
CAS No:26820-65-5
MF:C7H9N3O2
MW:167.165261030197
CID:252848
PubChem ID:12015727
Update Time:2025-05-19

2-Ethylamino-3-nitropyridine Chemical and Physical Properties

Names and Identifiers

    • 2-Pyridinamine,N-ethyl-3-nitro-
    • N-ethyl-3-nitropyridin-2-amine
    • 2-ethylamino-3-nitropyridine
    • 2-Pyridinamine,N-ethyl-3-nitro
    • N-ETHYL-3-NITRO-2-PYRIDINAMINE
    • N-ethyl-3-nitro-pyridin-2-amine
    • N-ethyl-3-nitropyridine-2-amine
    • PYR049
    • D75007
    • AKOS001874554
    • 26820-65-5
    • FT-0749934
    • ethyl-(3-nitro-pyridin-2-yl)-amine
    • CS-0090981
    • DTXSID70475867
    • A818615
    • BS-25363
    • BBA82065
    • 2-(ethylamino)-3-nitropyridine
    • SB52983
    • DDBQQNCEHLMYGB-UHFFFAOYSA-N
    • AM100600
    • SCHEMBL4034758
    • DB-050041
    • 2-Ethylamino-3-nitropyridine
    • Inchi: 1S/C7H9N3O2/c1-2-8-7-6(10(11)12)4-3-5-9-7/h3-5H,2H2,1H3,(H,8,9)
    • InChI Key: DDBQQNCEHLMYGB-UHFFFAOYSA-N
    • SMILES: [O-][N+](C1=CC=CN=C1NCC)=O

Computed Properties

  • Exact Mass: 167.06900
  • Monoisotopic Mass: 167.069476538g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 12
  • Rotatable Bond Count: 2
  • Complexity: 157
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 1.9
  • Topological Polar Surface Area: 70.7?2

Experimental Properties

  • Density: 1.281
  • Boiling Point: 298.572°C at 760 mmHg
  • Flash Point: 134.372°C
  • Refractive Index: 1.608
  • PSA: 70.74000
  • LogP: 2.01780

2-Ethylamino-3-nitropyridine Customs Data

  • HS CODE:2933399090
  • Customs Data:

    China Customs Code:

    2933399090

    Overview:

    2933399090. Other compounds with non fused pyridine rings in structure. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

    Summary:

    2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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2-Ethylamino-3-nitropyridine Production Method

Additional information on 2-Ethylamino-3-nitropyridine

2-Ethylamino-3-Nitropyridine: A Comprehensive Overview

2-Ethylamino-3-nitropyridine (CAS No. 26820-65-5) is a compound of significant interest in the fields of organic chemistry and materials science. This compound, with its unique structural features, has garnered attention due to its potential applications in various industries, including pharmaceuticals, agrochemicals, and advanced materials. In this article, we delve into the properties, synthesis, applications, and recent research advancements related to 2-Ethylamino-3-nitropyridine.

The molecular structure of 2-Ethylamino-3-nitropyridine consists of a pyridine ring with an ethylamino group at position 2 and a nitro group at position 3. This arrangement imparts distinctive electronic and steric properties to the molecule. The presence of the nitro group introduces electron-withdrawing effects, while the ethylamino group contributes electron-donating characteristics. This balance of electronic effects makes 2-Ethylamino-3-nitropyridine a versatile building block for various chemical transformations.

Recent studies have highlighted the potential of 2-Ethylamino-3-nitropyridine in the development of novel materials with tailored functionalities. For instance, researchers have explored its use as a precursor for synthesizing advanced polymers and coordination compounds. The compound's ability to act as a ligand in metal complexes has opened new avenues for its application in catalysis and sensing technologies.

In terms of synthesis, 2-Ethylamino-3-nitropyridine can be prepared through several routes. One common method involves the nucleophilic substitution reaction of 3-nitropyridine with ethylamine under specific conditions. Another approach utilizes coupling reactions involving appropriate intermediates. The choice of synthesis pathway depends on factors such as yield, cost-effectiveness, and scalability.

The physical properties of 2-Ethylamino-3-nitropyridine are equally intriguing. It exhibits a melting point of approximately 140°C and is sparingly soluble in common organic solvents such as dichloromethane and ethyl acetate. Its UV-vis spectrum reveals strong absorption bands in the visible region, which suggests potential applications in optoelectronic materials.

One of the most promising areas of research involving 2-Ethylamino-3-nitropyridine is its application in drug discovery. The compound's structural features make it an attractive candidate for designing bioactive molecules with specific pharmacological properties. Recent studies have demonstrated its ability to modulate key biological pathways, making it a potential lead compound for therapeutic development.

In addition to its chemical significance, 2-Ethylamino-3-nitropyridine has found niche applications in analytical chemistry. Its reactivity towards certain analytes makes it useful as a reagent in spectroscopic assays and chromatographic separations.

Looking ahead, ongoing research aims to further unlock the potential of 2-Ethylamino-3-nitropyridine by exploring its interactions with biological systems and developing novel synthetic methodologies. Collaborative efforts between chemists, biologists, and materials scientists are expected to drive innovation in this field.

In conclusion, 2-Ethylamino-3-nitropyridine (CAS No. 26820-65-5) stands out as a multifaceted compound with diverse applications across various disciplines. Its unique chemical properties and versatile reactivity continue to inspire groundbreaking research, positioning it as a key player in modern chemical science.

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