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• 2. An aptasensor for detection of potassium ions based on RecJf exonuclease mediated signal amplification
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• 3. An apparatus for determining small amounts of alchohol in sour milk and urine
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• Solvents and Organic Chemicals Organic Compounds Organic 1,3-dipolar compounds Allyl-type 1,3-dipolar organic compounds C-nitro compounds
• Solvents and Organic Chemicals Organic Compounds Organic 1,3-dipolar compounds Allyl-type 1,3-dipolar organic compounds Organic nitro compounds C-nitro compounds

Comprehensive Overview of 4-methyl-5-nitro-pyridine-2-carbonitrile (CAS No. 267875-30-9)

4-methyl-5-nitro-pyridine-2-carbonitrile (CAS No. 267875-30-9) is a specialized organic compound widely recognized in pharmaceutical and agrochemical research. This nitropyridine derivative has garnered significant attention due to its unique structural properties and potential applications in drug discovery and material science. The compound's molecular framework, featuring a nitro group and a cyano group on a pyridine ring, makes it a valuable intermediate for synthesizing more complex molecules. Researchers are particularly interested in its reactivity, which enables diverse chemical transformations, including nucleophilic substitutions and reduction reactions.

In recent years, the demand for nitropyridine derivatives like 4-methyl-5-nitro-pyridine-2-carbonitrile has surged, driven by their utility in developing novel therapeutic agents. For instance, similar compounds have been explored as kinase inhibitors or antimicrobial agents, aligning with the growing focus on targeted drug delivery and antibiotic resistance solutions. The compound's CAS No. 267875-30-9 is frequently searched in academic databases and chemical supplier catalogs, reflecting its relevance in modern synthetic chemistry.

From a synthetic perspective, 4-methyl-5-nitro-pyridine-2-carbonitrile is often prepared through nitration and cyanation reactions, with yields optimized for industrial-scale production. Its nitro group can be selectively reduced to an amine, opening pathways to heterocyclic scaffolds prevalent in FDA-approved drugs. This adaptability has positioned the compound as a key building block in medicinal chemistry, especially for projects involving structure-activity relationship (SAR) studies.

Beyond pharmaceuticals, 4-methyl-5-nitro-pyridine-2-carbonitrile finds niche applications in material science, where its electron-withdrawing groups contribute to the design of organic semiconductors and photoactive materials. These applications resonate with current trends in green chemistry and sustainable energy, as researchers seek eco-friendly alternatives to traditional materials. The compound’s thermal stability and solubility profile further enhance its versatility in formulation development.

Analytical characterization of CAS No. 267875-30-9 typically involves techniques like HPLC, NMR spectroscopy, and mass spectrometry, ensuring high purity for research use. Quality control protocols are critical, given the compound’s role in precision synthesis. Suppliers often highlight its ≥98% purity grade, catering to stringent laboratory requirements.

Environmental and safety considerations for 4-methyl-5-nitro-pyridine-2-carbonitrile align with standard laboratory practices. While not classified as hazardous under major regulatory frameworks, proper handling—including ventilation and PPE—is recommended due to its fine particulate nature. This aligns with broader industry shifts toward responsible chemical management and occupational safety.

In summary, 4-methyl-5-nitro-pyridine-2-carbonitrile (CAS No. 267875-30-9) exemplifies the intersection of innovation and practicality in modern chemistry. Its multifaceted applications, from drug discovery to advanced materials, underscore its importance in addressing contemporary scientific challenges. As interest grows in small-molecule therapeutics and functional materials, this compound is poised to remain a staple in research pipelines worldwide.

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