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Comprehensive Overview of 3-Benzofuranacetic acid, methyl ester (CAS No. 26278-23-9): Properties, Applications, and Market Trends

3-Benzofuranacetic acid, methyl ester (CAS No. 26278-23-9) is a specialized organic compound widely recognized for its unique structural features and versatile applications in pharmaceutical and agrochemical research. This ester derivative of benzofuran has garnered significant attention due to its potential as a building block in synthetic chemistry, particularly in the development of bioactive molecules. The compound's molecular formula, C₁₁H₁₀O₃, and its distinct benzofuran core make it a valuable intermediate for researchers exploring novel therapeutic agents.

In recent years, the demand for 3-Benzofuranacetic acid, methyl ester has surged, driven by its role in the synthesis of heterocyclic compounds. The benzofuran scaffold is a privileged structure in medicinal chemistry, often associated with anti-inflammatory, antimicrobial, and antioxidant properties. This aligns with current trends in drug discovery, where researchers prioritize sustainable synthesis and bioactive intermediates. A 2023 study highlighted its utility in optimizing drug-like properties, addressing frequent search queries like "benzofuran derivatives in drug design" or "CAS 26278-23-9 applications."

From a technical perspective, 3-Benzofuranacetic acid, methyl ester exhibits a melting point range of 45–48°C and a boiling point of approximately 285°C, making it suitable for controlled reactions under moderate conditions. Its solubility profile—moderate in organic solvents like ethanol and acetone but low in water—facilitates its use in green chemistry protocols, a topic increasingly searched alongside "eco-friendly chemical synthesis." Analytical techniques such as HPLC and GC-MS are commonly employed for purity verification, reflecting industry standards for high-precision intermediates.

The compound's relevance extends to material science, where its aromatic heterocycle contributes to the development of organic semiconductors and luminescent materials. This connects with trending searches on "benzofuran-based electronic materials" and "CAS 26278-23-9 in optoelectronics." Manufacturers emphasize strict quality control (typically ≥98% purity) to meet the needs of advanced applications, underscoring its role in cutting-edge R&D.

Regulatory compliance and safety data for 3-Benzofuranacetic acid, methyl ester adhere to global standards like REACH and OSHA. While not classified as hazardous under normal handling conditions, proper storage (cool, dry environments) is recommended to preserve stability—a detail often queried as "CAS 26278-23-9 storage guidelines." The compound's non-toxic profile at standard concentrations further enhances its appeal for industrial-scale use.

Market analysts note growing interest in custom synthesis services for 26278-23-9, particularly from regions with robust pharmaceutical sectors like North America and Asia-Pacific. This trend mirrors search patterns around "bulk suppliers of benzofuran esters" and "cost-effective chemical intermediates." Innovations in catalytic esterification methods have also improved production efficiency, addressing sustainability concerns frequently raised in chemical industry forums.

In conclusion, 3-Benzofuranacetic acid, methyl ester (CAS No. 26278-23-9) represents a critical intersection of chemistry and innovation. Its multifaceted applications—from drug discovery to advanced materials—position it as a compound of enduring scientific and commercial value. As research continues to explore its potential, this benzofuran derivative is poised to remain a focal point in discussions about next-generation chemical solutions.

• 53906-90-4(5-methyl-2-Furanacetic acid ethyl ester)
• 1005328-52-8(Methyl 2-(5-chlorobenzofuran-2-yl)acetate)
• 408506-61-6(Ethyl 2-(5-bromobenzofuran-2-yl)acetate)
• 1005328-51-7(Methyl 2-(5-methoxybenzofuran-2-yl)acetate)
• 387400-92-2(Methyl 2-(5-hydroxybenzofuran-2-yl)acetate)
• 39581-61-8(methyl 2-(1-benzofuran-2-yl)acetate)
• 4915-21-3(ethyl 2-(furan-2-yl)acetate)
• 4915-22-4(2-Furanacetic acid, methyl ester)
• 60670-00-0(methyl 2-(5-methylfuran-2-yl)acetate)
• 62119-70-4(2-(1-benzofuran-2-yl)acetic acid)