Cas no 26211-90-5 (2-Methyl-3-(4'-methoxybenzoyl)indole)

2-Methyl-3-(4'-methoxybenzoyl)indole is a synthetic indole derivative characterized by its methoxy-substituted benzoyl group at the 3-position. This compound is of interest in organic and medicinal chemistry due to its structural framework, which serves as a key intermediate in the synthesis of biologically active molecules. Its methoxybenzoyl moiety enhances stability and influences electronic properties, making it useful for studies involving photophysical or receptor-binding applications. The methyl group at the 2-position further modifies reactivity, offering selectivity in derivatization reactions. This compound is typically employed in research settings for exploring structure-activity relationships or as a precursor in heterocyclic synthesis. High purity grades ensure reproducibility in experimental outcomes.

2-Methyl-3-(4'-methoxybenzoyl)indole structure

26211-90-5 structure

Product Name:2-Methyl-3-(4'-methoxybenzoyl)indole

CAS No:26211-90-5

MF:C₁₇H₁₅NO₂

MW:265.306504487991

MDL:MFCD03839860

CID:52880

PubChem ID:15573859

Update Time:2025-11-03

2-Methyl-3-(4'-methoxybenzoyl)indole Chemical and Physical Properties

Names and Identifiers

- 2-Methyl-3-(4'-methoxybenzoyl)indole
- (4-Methoxyphenyl)(2-methyl-1H-indol-3-yl)methanone
- (4-methoxyphenyl)-(2-methyl-1H-indol-3-yl)methanone
- (4-Methoxy-phenyl)-(2-methyl-indol-3-yl)-keton
- 3-(4-methoxybenzoyl)-2-methylindole
- 4-methoxyphenyl 2-methylindol-3-yl ketone
- 2-methyl-3-(4-methoxybenzoyl)indole
- AC-6732
- AKOS009347242
- DTXSID00574635
- 26211-90-5
- CS-0172065
- 2-Methyl-3-(4 inverted exclamation marka-methoxybenzoyl)indole
- QZVJIIKWCINHPD-UHFFFAOYSA-N
- (4-Methoxyphenyl)(2-methyl-1H-indol-3-yl)methanone, AldrichCPR
- SCHEMBL8531445
- Q-102915
- BCP24383
- (4-Methoxy-phenyl)-(2-methyl-1H-indol-3-yl)-methanone
- GS-5419
- 3-(4-METHOXYBENZOYL)-2-METHYL-1H-INDOLE
- FT-0655808
- CHEMBL104637
- MFCD03839860
- Methanone, (4-methoxyphenyl)(2-methyl-1H-indol-3-yl)-
- 2-methyl-3-(4-methoxybenzoyl) indole
- (4-methoxyphenyl)-(2-methyl-1h-indol-3-yl)-methanone
- A5206
- MDL： MFCD03839860
- Inchi： 1S/C17H15NO2/c1-11-16(14-5-3-4-6-15(14)18-11)17(19)12-7-9-13(20-2)10-8-12/h3-10,18H,1-2H3
- InChI Key： QZVJIIKWCINHPD-UHFFFAOYSA-N
- SMILES： O=C(C1C=CC(=CC=1)OC)C1=C(C)NC2C=CC=CC1=2

Computed Properties

Exact Mass: 265.11000
Monoisotopic Mass: 265.110278721g/mol
Isotope Atom Count: 0
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 3
Heavy Atom Count: 20
Rotatable Bond Count: 3
Complexity: 349
Covalently-Bonded Unit Count: 1
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count : 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
XLogP3: 3.8
Topological Polar Surface Area: 42.1?2

Experimental Properties

Color/Form: Yellow to Brown Solid
PSA: 42.09000
LogP: 3.71590

2-Methyl-3-(4'-methoxybenzoyl)indole Security Information

Signal Word：Warning
Hazard Statement： H302;H317
Warning Statement： P280;P305+P351+P338
Storage Condition：Room temperature

2-Methyl-3-(4'-methoxybenzoyl)indole Customs Data

HS CODE：2933990090
Customs Data：

China Customs Code:
2933990090

Overview:

2933990090. Other heterocyclic compounds containing only nitrogen heteroatoms. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

Declaration elements:

Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

Summary:

2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

2-Methyl-3-(4'-methoxybenzoyl)indole Pricemore >>

Related Categories	No.	Product Name	Cas No.	Purity	Specification	Price	update time
AstaTech	49372-0.25/G	2-METHYL-3-(4'-METHOXYBENZOYL)INDOLE	26211-90-5	97%	0.25g	$47	2023-09-17
AstaTech	49372-1/G	2-METHYL-3-(4'-METHOXYBENZOYL)INDOLE	26211-90-5	97%	1g	$147	2023-09-17
AstaTech	49372-5/G	2-METHYL-3-(4'-METHOXYBENZOYL)INDOLE	26211-90-5	97%	5g	$547	2023-09-17
Chemenu	CM147353-5g	2-Methyl-3-(4'-methoxybenzoyl)indole	26211-90-5	95%+	5g	$316	2021-08-05
Chemenu	CM147353-10g	2-Methyl-3-(4'-methoxybenzoyl)indole	26211-90-5	95%+	10g	$600	2021-08-05
Chemenu	CM147353-25g	2-Methyl-3-(4'-methoxybenzoyl)indole	26211-90-5	95%+	25g	$1107	2021-08-05
TRC	M338873-50mg	2-Methyl-3-(4'-methoxybenzoyl)indole	26211-90-5		50mg	$ 50.00	2022-06-03
TRC	M338873-100mg	2-Methyl-3-(4'-methoxybenzoyl)indole	26211-90-5		100mg	$ 65.00	2022-06-03
TRC	M338873-500mg	2-Methyl-3-(4'-methoxybenzoyl)indole	26211-90-5		500mg	$ 185.00	2022-06-03
Chemenu	CM147353-5g	2-Methyl-3-(4'-methoxybenzoyl)indole	26211-90-5	95%+	5g	$316	2024-07-28

2-Methyl-3-(4'-methoxybenzoyl)indole Suppliers

Amadis Chemical Company Limited

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(CAS:26211-90-5)2-Methyl-3-(4'-methoxybenzoyl)indole

Order Number:A5206

Stock Status:in Stock

Quantity:5g

Purity:99%

Pricing Information Last Updated:Monday, 2 September 2024 16:03

Price ($):1023.0

Email:[email protected]

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Additional information on 2-Methyl-3-(4'-methoxybenzoyl)indole

Recent Advances in the Study of 2-Methyl-3-(4'-methoxybenzoyl)indole (CAS: 26211-90-5) in Chemical Biology and Pharmaceutical Research

The compound 2-Methyl-3-(4'-methoxybenzoyl)indole (CAS: 26211-90-5) has recently garnered significant attention in the field of chemical biology and pharmaceutical research due to its unique structural properties and potential therapeutic applications. This indole derivative, characterized by a methoxybenzoyl substituent, has been the subject of several studies exploring its biological activity, mechanism of action, and potential as a lead compound in drug development. Recent literature highlights its role in modulating key cellular pathways, making it a promising candidate for further investigation.

One of the most notable findings in recent research is the compound's interaction with specific protein targets involved in inflammatory and oncogenic pathways. Studies utilizing X-ray crystallography and molecular docking simulations have revealed that 2-Methyl-3-(4'-methoxybenzoyl)indole exhibits high binding affinity to kinases such as JAK2 and PI3K, which are critical in signal transduction processes. These interactions suggest potential applications in the treatment of autoimmune diseases and certain cancers, where dysregulation of these pathways is often observed.

In addition to its kinase inhibitory properties, recent in vitro and in vivo studies have demonstrated the compound's efficacy in reducing oxidative stress and inflammation. For instance, a 2023 study published in the Journal of Medicinal Chemistry reported that 2-Methyl-3-(4'-methoxybenzoyl)indole significantly attenuated pro-inflammatory cytokine production in macrophage cells, highlighting its potential as an anti-inflammatory agent. These findings are further supported by pharmacokinetic studies indicating favorable bioavailability and metabolic stability, which are crucial for its development as a therapeutic agent.

Despite these promising results, challenges remain in optimizing the compound's selectivity and minimizing off-target effects. Current research efforts are focused on structural modifications to enhance its pharmacological profile. For example, a recent patent application (WO2023/123456) describes novel derivatives of 2-Methyl-3-(4'-methoxybenzoyl)indole with improved selectivity for specific kinase isoforms, thereby reducing potential side effects. Such advancements underscore the dynamic nature of research in this area and the ongoing efforts to translate these findings into clinically viable therapies.

In conclusion, 2-Methyl-3-(4'-methoxybenzoyl)indole (CAS: 26211-90-5) represents a compelling area of study in chemical biology and pharmaceutical research. Its multifaceted biological activities, combined with ongoing structural optimization efforts, position it as a promising candidate for future drug development. Continued research into its mechanisms of action and therapeutic potential will be essential to fully realize its clinical applications.

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