Cas no 26130-02-9 (Frentizole)

Frentizole is an immunomodulatory compound primarily studied for its potential therapeutic applications in autoimmune and inflammatory conditions. Chemically classified as a substituted imidazole derivative, it exhibits selective immunosuppressive properties by modulating lymphocyte activity. Its mechanism of action involves inhibition of T-cell proliferation, making it a candidate for research in transplant rejection and autoimmune disorders. Frentizole demonstrates favorable bioavailability and metabolic stability in preclinical studies. The compound's targeted activity may offer advantages over broader immunosuppressants by potentially reducing off-target effects. Further investigation is required to fully elucidate its pharmacokinetic profile and clinical applicability. Current research focuses on optimizing its therapeutic window and specificity.
Frentizole structure
Frentizole structure
Product Name:Frentizole
CAS No:26130-02-9
MF:C15H13N3O2S
MW:299.347621679306
CID:258480
PubChem ID:33334
Update Time:2025-10-05

Frentizole Chemical and Physical Properties

Names and Identifiers

    • Urea,N-(6-methoxy-2-benzothiazolyl)-N'-phenyl-
    • Frentizole
    • 1-(6-methoxy-2-benzothiazolyl)-3-phenylurea
    • 1-(6-methoxybenzo[d]thiazol-2-yl)-3-phenylurea
    • 1-(6-methoxy-benzothiazol-2-yl)-3-phenyl-urea
    • Compound 53616
    • DSSTox_CID_26279
    • DSSTox_GSID_46279
    • DSSTox_RID_81505
    • Frentizol
    • N-[6-Methoxybenzo[d]thiazol-2-yl]-N'-phenylurea
    • Urea, N-(6-methoxy-2-benzothiazolyl)-N'-phenyl-
    • AKOS001049350
    • 1-(6-METHOXY-3H-BENZOTHIAZOL-2-YLIDENE)-3-PHENYL-UREA
    • MLS001201824
    • BDBM50189352
    • 7EY946394I
    • FRENTIZOLE [USAN]
    • N-(6-methoxy-1,3-benzothiazol-2-yl)-N'-phenylurea
    • BRD-K07202345-001-15-2
    • NCGC00160657-01
    • LY 53616
    • FRENTIZOLE [WHO-DD]
    • 1-(6-methoxybenzothiazol-2-yl)-3-phenylurea
    • CHEMBL128988
    • CAS-26130-02-9
    • MLS000555007
    • DTXSID5046279
    • COMPOUND-53616
    • SMR000147124
    • Frentizole (USAN/INN)
    • Tox21_111964_1
    • 26130-02-9
    • SCHEMBL599582
    • Frentizolum
    • FRENTIZOLE [INN]
    • Frentizol [INN-Spanish]
    • Frentizolum [INN-Latin]
    • HMS2233G12
    • F21331
    • s2418
    • cid_33334
    • Tox21_111964
    • Opera_ID_1653
    • 3-(6-methoxy-1,3-benzothiazol-2-yl)-1-phenylurea
    • Frentizole [USAN:INN:BAN]
    • EN300-1700017
    • HY-15374
    • 1-(6-methoxy-1,3-benzothiazol-2-yl)-3-phenylurea
    • BS-42180
    • CS-0841
    • Oprea1_516941
    • Q27268177
    • Z44584301
    • DTXCID3026279
    • HMS3370C02
    • BBA13002
    • NCGC00160657-03
    • D00159
    • UNII-7EY946394I
    • NS00122519
    • SCHEMBL18313924
    • BRD-K07202345-001-19-4
    • STK078558
    • DA-63613
    • MDL: MFCD00030234
    • Inchi: 1S/C15H13N3O2S/c1-20-11-7-8-12-13(9-11)21-15(17-12)18-14(19)16-10-5-3-2-4-6-10/h2-9H,1H3,(H2,16,17,18,19)
    • InChI Key: JHBWYQRKOUBPCA-UHFFFAOYSA-N
    • SMILES: S1C(NC(NC2C=CC=CC=2)=O)=NC2C=CC(=CC1=2)OC

Computed Properties

  • Exact Mass: 299.07284784g/mol
  • Monoisotopic Mass: 299.07284784g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 5
  • Heavy Atom Count: 21
  • Rotatable Bond Count: 5
  • Complexity: 363
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 3.2
  • Topological Polar Surface Area: 91.5?2

Experimental Properties

  • Density: 1.420±0.06 g/cm3 (20 oC 760 Torr),
  • Solubility: Insuluble (7.8E-3 g/L) (25 oC),

Frentizole Security Information

  • Storage Condition:Powder -20°C 3 years ? 4°C 2 years In solvent -80°C 6 months ? -20°C 1 month

Frentizole Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
MedChemExpress
HY-15374-10mM*1mLinDMSO
Frentizole
26130-02-9 99.37%
10mM*1mLinDMSO
¥1125 2022-05-18
MedChemExpress
HY-15374-5mg
Frentizole
26130-02-9 99.21%
5mg
¥600 2024-04-18
MedChemExpress
HY-15374-10mg
Frentizole
26130-02-9 99.21%
10mg
¥950 2024-04-18
SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd.
F126701-20mg
Frentizole
26130-02-9 ≥98%
20mg
¥3,837.00 2021-05-25
SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd.
F126701-5mg
Frentizole
26130-02-9 ≥98%
5mg
¥555.90 2023-09-02
SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd.
F126701-10mg
Frentizole
26130-02-9 ≥98%
10mg
¥615.90 2023-09-02
DC Chemicals
DC9344-100 mg
Frentizole
26130-02-9 >98%
100mg
$500.0 2022-02-28
DC Chemicals
DC9344-250 mg
Frentizole
26130-02-9 >98%
250mg
$1000.0 2022-02-28
DC Chemicals
DC9344-1 g
Frentizole
26130-02-9 >98%
1g
$2000.0 2022-02-28
S e l l e c k ZHONG GUO
S2418-5mg
Frentizole
26130-02-9 99.95%
5mg
¥1070.13 2023-09-15

Additional information on Frentizole

Frentizole (CAS No. 26130-02-9): A Comprehensive Overview

Frentizole, with the Chemical Abstracts Service (CAS) number 26130-02-9, is a compound that has garnered significant attention in the field of medicinal chemistry and pharmaceutical research. This compound is known for its unique chemical structure and potential therapeutic applications, making it a subject of extensive study in both academic and industrial settings.

The chemical structure of Frentizole is characterized by its specific molecular formula and functional groups, which contribute to its pharmacological properties. Recent advancements in analytical techniques have allowed researchers to gain deeper insights into the molecular dynamics and interactions of Frentizole. These studies have highlighted its potential as a lead compound for the development of novel drugs targeting various diseases.

In the realm of medicinal chemistry, Frentizole has shown promising results in preclinical studies. Its ability to modulate specific biological pathways has been extensively investigated, with a focus on its potential as an anti-inflammatory agent and its role in neuroprotection. Research published in leading scientific journals has demonstrated that Frentizole can effectively reduce inflammation and oxidative stress, making it a valuable candidate for the treatment of conditions such as Alzheimer's disease and multiple sclerosis.

The pharmacokinetic properties of Frentizole have also been a subject of interest. Studies have shown that it exhibits favorable absorption, distribution, metabolism, and excretion (ADME) profiles, which are crucial for its therapeutic efficacy. These properties make it an attractive candidate for further clinical development. Additionally, the compound's low toxicity and high selectivity enhance its safety profile, reducing the risk of adverse effects in patients.

One of the key areas of research involving Frentizole is its potential as an antiviral agent. Recent studies have explored its ability to inhibit viral replication, particularly in the context of emerging viral infections. This has led to increased interest in developing Frentizole-based therapies for viral diseases, including those caused by RNA viruses such as influenza and coronaviruses. The antiviral activity of Frentizole is attributed to its ability to interfere with viral entry and replication processes, making it a promising candidate for broad-spectrum antiviral applications.

Beyond its therapeutic applications, Frentizole has also been studied for its potential use in diagnostic imaging. Its unique chemical properties make it suitable for use as a contrast agent in various imaging modalities, such as magnetic resonance imaging (MRI) and computed tomography (CT). This dual functionality—therapeutic and diagnostic—positions Frentizole as a versatile compound with broad applications in medical research and clinical practice.

The development of novel formulations of Frentizole has also been an area of active research. Scientists are exploring different delivery systems to enhance the bioavailability and efficacy of the compound. Nanotechnology-based approaches, such as liposomal formulations and nanoparticle delivery systems, have shown promise in improving the pharmacological properties of Frentizole. These advanced delivery systems can target specific tissues or cells, thereby increasing the therapeutic index and reducing systemic side effects.

In conclusion, Frentizole (CAS No. 26130-02-9) is a multifaceted compound with significant potential in various areas of medical research and pharmaceutical development. Its unique chemical structure, favorable pharmacokinetic properties, and diverse therapeutic applications make it an exciting subject for ongoing research. As new findings continue to emerge, the role of Frentizole in advancing medical science is likely to expand, contributing to the development of innovative treatments for a wide range of diseases.

Recommended suppliers
Shandong Jing Kun Chemical Co.,Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Shandong Jing Kun Chemical Co.,Ltd.
Hebei Liye chemical Co.,Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Hebei Liye chemical Co.,Ltd
Hunan Well Medicine Synthesis Technology Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
Hunan Well Medicine Synthesis Technology Co., Ltd.
Wuhan Comings Biotechnology Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Wuhan Comings Biotechnology Co., Ltd.
Amadis Chemical Company Limited
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
Amadis Chemical Company Limited