Cas no 259143-03-8 (tert-Butyl 4-(fluoromethyl)piperidine-1-carboxylate)

Tert-Butyl 4-(fluoromethyl)piperidine-1-carboxylate is a fluorinated piperidine derivative commonly used as an intermediate in organic synthesis and pharmaceutical research. Its key structural features include a Boc-protected amine group and a fluoromethyl substituent, enhancing its utility in the development of bioactive molecules. The Boc group offers stability under various reaction conditions while allowing selective deprotection when needed. The fluoromethyl moiety can improve metabolic stability and binding affinity in drug candidates. This compound is particularly valuable in medicinal chemistry for the design of CNS-targeting agents and protease inhibitors. It is typically handled under inert conditions due to its sensitivity to moisture and strong acids/bases.
tert-Butyl 4-(fluoromethyl)piperidine-1-carboxylate structure
259143-03-8 structure
Product Name:tert-Butyl 4-(fluoromethyl)piperidine-1-carboxylate
CAS No:259143-03-8
MF:C11H20FNO2
MW:217.280406951904
MDL:MFCD11054100
CID:1068703
PubChem ID:10608815
Update Time:2025-10-28

tert-Butyl 4-(fluoromethyl)piperidine-1-carboxylate Chemical and Physical Properties

Names and Identifiers

    • tert-Butyl 4-(fluoromethyl)piperidine-1-carboxylate
    • 1-N-Boc-4-fluoromethylpiperidine
    • N-BOC-4-fluoromethylpiperidine
    • {4-(fluoromethyl)benzene}boronic acid
    • 4-fluoromethyl-phenyl boronic acid
    • 4-fluoromethylphenylboronic acid
    • 4-fluoromethylpiperidine-1-carboxylic acid tert-butyl ester
    • AGN-PC-01VC98
    • Boronic acid, [4-(fluoromethyl)phenyl]-
    • Boronic acid, [4-(fluoromethyl)phenyl]- (9CI)
    • D-1625
    • SureCN1191308
    • 4-Fluoromethyl-piperidine-1-carboxylic acid tert-butyl ester
    • DB-371433
    • AS-68832
    • SY102688
    • F1907-0035
    • tert-Butyl4-(fluoromethyl)piperidine-1-carboxylate
    • 1-Boc-4-(fluoromethyl)piperidine
    • SCHEMBL4929702
    • AKOS015949502
    • JPONZPZEVAZHJW-UHFFFAOYSA-N
    • PB31528
    • CS-W001517
    • MFCD11054100
    • W-206992
    • 259143-03-8
    • EN300-243776
    • P11048
    • MDL： MFCD11054100
    • Inchi： 1S/C11H20FNO2/c1-11(2,3)15-10(14)13-6-4-9(8-12)5-7-13/h9H,4-8H2,1-3H3
    • InChI Key： JPONZPZEVAZHJW-UHFFFAOYSA-N
    • SMILES： FCC1CCN(C(=O)OC(C)(C)C)CC1

Computed Properties

  • Exact Mass: 217.1479
  • Monoisotopic Mass: 217.14780704g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 15
  • Rotatable Bond Count: 4
  • Complexity: 217
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 2.2
  • Topological Polar Surface Area: 29.5?2

Experimental Properties

  • PSA: 29.54

tert-Butyl 4-(fluoromethyl)piperidine-1-carboxylate Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
Chemenu
CM295582-1g
tert-Butyl 4-(fluoromethyl)piperidine-1-carboxylate
 259143-03-8 95%
1g
 $463 2021-08-18
Chemenu
CM295582-5g
tert-Butyl 4-(fluoromethyl)piperidine-1-carboxylate
 259143-03-8 95%
5g
 $1388 2021-08-18
SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd.
N17470-1g
1-N-Boc-4-Fluoromethylpiperidine
 259143-03-8
1g
 ￥3220.0 2021-09-08
SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd.
N17470-500mg
1-N-Boc-4-Fluoromethylpiperidine
 259143-03-8
500mg
 ￥1930.0 2021-09-08
TRC
B814885-10mg
tert-butyl 4-(fluoromethyl)piperidine-1-carboxylate
 259143-03-8
10mg
 $ 50.00 2022-06-06
TRC
B814885-50mg
tert-butyl 4-(fluoromethyl)piperidine-1-carboxylate
 259143-03-8
50mg
 $ 160.00 2022-06-06
TRC
B814885-100mg
tert-butyl 4-(fluoromethyl)piperidine-1-carboxylate
 259143-03-8
100mg
 $ 250.00 2022-06-06
Alichem
A129000100-250mg
1-N-Boc-4-fluoromethylpiperidine
 259143-03-8 95%
250mg
 $700.40 2023-09-02
Alichem
A129000100-500mg
1-N-Boc-4-fluoromethylpiperidine
 259143-03-8 95%
500mg
 $1078.00 2023-09-02
Alichem
A129000100-1g
1-N-Boc-4-fluoromethylpiperidine
 259143-03-8 95%
1g
 $1651.30 2023-09-02

tert-Butyl 4-(fluoromethyl)piperidine-1-carboxylate Related Literature

Related Categories

259143-03-8 (tert-Butyl 4-(fluoromethyl)piperidine-1-carboxylate) Related Products

Recommended suppliers
Shanghai Jinhuan Chemical CO., LTD.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Shanghai Jinhuan Chemical CO., LTD.
Jinan Hanyu Chemical Co.,Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Jinan Hanyu Chemical Co.,Ltd.
上海帛亦醫(yī)藥科技有限公司
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
Shenzhen GeneSeqTools Bioscience & Technology Co. Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
Shenzhen GeneSeqTools Bioscience & Technology Co. Ltd.
Essenoi Fine Chemical Co., Limited
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent