Cas no 25805-17-8 (poly(2-ethyl-2-oxazoline))

Poly(2-ethyl-2-oxazoline) (PEtOx) is a water-soluble, biocompatible polymer belonging to the poly(2-oxazoline) family. Its key advantages include high stability, tunable solubility, and low immunogenicity, making it suitable for biomedical and pharmaceutical applications. PEtOx exhibits excellent stealth properties, reducing protein adsorption and extending circulation time in vivo, which is beneficial for drug delivery systems. The polymer’s thermoresponsive behavior and ability to form hydrogels further enhance its utility in controlled-release formulations. Additionally, PEtOx is resistant to hydrolysis and enzymatic degradation, ensuring long-term performance. Its versatility in conjugation chemistry allows for functionalization with bioactive molecules, broadening its applicability in diagnostics and therapeutics.
poly(2-ethyl-2-oxazoline) structure
poly(2-ethyl-2-oxazoline) structure
Product Name:poly(2-ethyl-2-oxazoline)
CAS No:25805-17-8
MF:C5H9NO
MW:99.1310613155365
MDL:MFCD00134377
CID:88625
PubChem ID:329755641
Update Time:2025-10-31

poly(2-ethyl-2-oxazoline) Chemical and Physical Properties

Names and Identifiers

    • poly(2-ethyl-2-oxazoline)
    • POLY(2-ETHYL-2-OXAZOLINE), MW 200,000
    • 2-ethyl-2-oxazoline homopolymer
    • 2-ethyl-4,5-dihydro-oxazolhomopolymer
    • MW5000
    • PEOX
    • PEOX,POx,PetOx
    • PetOx
    • poly 2-ethyloxazoline
    • Poly(2-ethyl-2-oxazoline), M.W. 500,000
    • polyethyloxazoline
    • POx
    • Q26218964
    • EINECS 233-912-4
    • 2-Ethyl-2-oxazoline
    • E78873
    • 2-Oxazoline, 2-ethyl-
    • ethyl oxazoline
    • NS00015772
    • W-110272
    • NSC 136557
    • NSC136557
    • MFCD00005302
    • FT-0612270
    • 10431-98-8
    • SY011237
    • UNII-B8CD92T4P5
    • AM84318
    • 2-Ethyloxazoline
    • Oxazole, 2-ethyl-4,5-dihydro-
    • NSC-136557
    • AKOS015912733
    • Z-1053
    • InChI=1/C5H9NO/c1-2-5-6-3-4-7-5/h2-4H2,1H
    • 2-Ethyl-2-oxazoline, >=99%
    • Oxazole,5-dihydro-
    • E0373
    • F0001-0097
    • 2-Ethyl-4,5-dihydro-oxazole
    • starbld0019600
    • 2-Ethyl-4,5-dihydro-1,3-oxazole #
    • 2-Ethyl-4,5-dihydro-1,3-oxazole
    • B8CD92T4P5
    • 2-ethyl-4,5-dihydrooxazole
    • FT-0699359
    • DTXSID9065075
    • 25805-17-8
    • A800954
    • DB-040532
    • MW inverted exclamation markO 200,000
    • UNII-HNX7574GTX
    • MDL: MFCD00134377
    • Inchi: 1S/C5H9NO/c1-2-5-6-3-4-7-5/h2-4H2,1H3
    • InChI Key: NYEZZYQZRQDLEH-UHFFFAOYSA-N
    • SMILES: O1C(CC)=NCC1

Computed Properties

  • Exact Mass: 99.06840
  • Monoisotopic Mass: 99.068414
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 7
  • Rotatable Bond Count: 1
  • Complexity: 88.1
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • XLogP3: 0.3
  • Topological Polar Surface Area: 21.6

Experimental Properties

  • Color/Form: Quasi white solid
  • Density: 1.14?g/mL?at 25?°C(lit.)
  • Melting Point: >300 °C
  • Boiling Point: 128.4 oCat 760 mmHg
  • Flash Point: 29.4 oC
  • Refractive Index: n20/D 1.52
  • Water Partition Coefficient: Soluble in water and organic solvents.
  • PSA: 21.59000
  • LogP: 0.26070
  • Solubility: Not determined

poly(2-ethyl-2-oxazoline) Security Information

  • Hazardous Material transportation number:NONH for all modes of transport
  • WGK Germany:3
  • TSCA:Yes

poly(2-ethyl-2-oxazoline) Pricemore >>

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abcr
AB210547-100 g
Poly(2-ethyl-2-oxazoline), MW 500,000; .
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€61.90 2023-07-20
abcr
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abcr
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poly(2-ethyl-2-oxazoline) Related Literature

Additional information on poly(2-ethyl-2-oxazoline)

Poly(2-Ethyl-2-Oxazoline): A Comprehensive Overview

Poly(2-Ethyl-2-Oxazoline), commonly referred to as PEO or polyoxazoline, is a synthetic polymer with the CAS registry number 25805-17-8. This polymer is widely recognized for its unique properties, including excellent thermal stability, high mechanical strength, and versatile chemical functionality. The structure of poly(2-Ethyl-2-Oxazoline) consists of repeating units of 2-Ethyl-2-Oxazoline monomers, which are five-membered heterocyclic rings containing an oxygen atom and an ethyl substituent. These structural features contribute to its distinctive behavior in various applications.

One of the most notable aspects of poly(2-Ethyl-2-Oxazoline) is its ability to form well-defined block copolymers with other monomers. This capability has been extensively explored in recent studies, particularly in the development of advanced materials for biomedical applications. For instance, researchers have demonstrated that block copolymers of PEO with hydrophilic segments can serve as effective drug delivery systems due to their controlled release properties. These findings highlight the potential of poly(2-Ethyl-2-Oxazoline) in the field of biomedical engineering, where precise control over polymer behavior is crucial.

Another area where poly(2-Ethyl-2-Oxazoline) has shown significant promise is in the field of electronic materials. Recent advancements have focused on incorporating PEO into polymer electrolytes for lithium-ion batteries. The high ionic conductivity and excellent electrochemical stability of poly(2-Ethyl-2-Oxazoline) make it an ideal candidate for enhancing battery performance. Studies have shown that blends of PEO with lithium salts exhibit superior ion transport properties, which could lead to more efficient and longer-lasting batteries.

The synthesis of poly(2-Ethyl-2-Oxazoline) typically involves free radical polymerization or controlled radical polymerization techniques such as atom transfer radical polymerization (ATRP). These methods allow for precise control over the molecular weight and polydispersity of the resulting polymer, which is essential for tailoring its properties for specific applications. Recent research has also explored the use of green chemistry approaches to synthesize PEO, reducing environmental impact while maintaining high-quality polymer products.

In terms of applications, poly(2-Ethyl-2-Oxazoline) has found use in a wide range of industries, including coatings, adhesives, and textiles. Its ability to form strong intermolecular hydrogen bonds makes it highly effective as a thickening agent and rheology modifier in formulations. Additionally, the polymer's resistance to UV degradation and excellent thermal stability make it suitable for high-performance materials in harsh environments.

Recent studies have also investigated the potential of poly(2-Ethyl-2-Oxazoline) in water treatment applications. Researchers have developed membranes based on PEO that exhibit high selectivity and permeability for separating contaminants from water. These membranes are being tested for their scalability and durability under real-world conditions, which could pave the way for innovative solutions in water purification technologies.

In conclusion, poly(2-Ethyl-2-Oxazoline) (CAS No. 25805-17-8) is a versatile polymer with a wide range of applications across multiple industries. Its unique structural properties, combined with recent advancements in synthesis and application development, position it as a key material in modern material science. As research continues to uncover new possibilities for this polymer, its role in shaping future technologies is expected to grow significantly.

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