Cas no 25682-47-7 (8,11-diazatricyclo4.3.3.0,1,6dodecane)

8,11-Diazatricyclo[4.3.3.0,1,6]dodecane is a structurally complex heterocyclic compound featuring a tricyclic framework with two nitrogen atoms incorporated at the 8 and 11 positions. Its rigid, cage-like architecture and nitrogen-rich core make it a valuable scaffold in medicinal chemistry and material science. The compound exhibits notable stability due to its constrained geometry, which minimizes conformational flexibility and enhances binding affinity in host-guest interactions. Its unique structure is particularly advantageous for designing enzyme inhibitors, receptor ligands, or supramolecular building blocks. The presence of nitrogen atoms allows for further functionalization, enabling tailored modifications for specific applications. This compound's synthetic versatility and structural precision contribute to its utility in advanced research and development contexts.
8,11-diazatricyclo4.3.3.0,1,6dodecane structure
25682-47-7 structure
Product Name:8,11-diazatricyclo4.3.3.0,1,6dodecane
CAS No:25682-47-7
MF:C10H18N2
MW:166.263322353363
CID:260402
PubChem ID:129930528
Update Time:2025-06-19

8,11-diazatricyclo4.3.3.0,1,6dodecane Chemical and Physical Properties

Names and Identifiers

    • 1H,4H-3a,6a-Butanopyrrolo[3,4-c]pyrrole,tetrahydro- (8CI,9CI)
    • 8,11-Diaza[4.3.3]propellane
    • 1H,4H-3a,6a-Butanopyrrolo[3,4-c]pyrrole, tetrahydro- (8CI,9CI)
    • 8,11-diazatricyclo4.3.3.0,1,6dodecane
    • Inchi: 1S/C10H18N2/c1-2-4-10-7-11-5-9(10,3-1)6-12-8-10/h11-12H,1-8H2
    • InChI Key: UROLBHUIXNFDAP-UHFFFAOYSA-N
    • SMILES: N1CC23CCCCC2(CNC3)C1

8,11-diazatricyclo4.3.3.0,1,6dodecane Pricemore >>

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Additional information on 8,11-diazatricyclo4.3.3.0,1,6dodecane

Introduction to Compound with CAS No. 25682-47-7 and Product Name: 8,11-diazatricyclo4.3.3.0,1,6dodecane

The compound with the CAS number 25682-47-7 and the product name 8,11-diazatricyclo4.3.3.0,1,6dodecane represents a significant advancement in the field of organic chemistry and pharmaceutical research. This compound belongs to a class of tricyclic amines, which have garnered considerable attention due to their unique structural properties and potential applications in medicinal chemistry.

The molecular structure of 8,11-diazatricyclo4.3.3.0,1,6dodecane features a tricyclic framework with two nitrogen atoms incorporated into the ring system. This configuration imparts distinct electronic and steric properties to the molecule, making it a versatile scaffold for drug design. The presence of nitrogen atoms in the ring enhances the compound's ability to interact with biological targets, particularly enzymes and receptors involved in various metabolic pathways.

Recent studies have highlighted the importance of tricyclic compounds in the development of novel therapeutic agents. The rigid three-dimensional structure of these molecules often provides improved binding affinity and selectivity compared to linear or cyclic analogs. This characteristic has made tricyclic amines particularly attractive for targeting proteins that exhibit conformational flexibility or require precise spatial orientation for effective interaction.

In particular, 8,11-diazatricyclo4.3.3.0,1,6dodecane has been investigated for its potential role in modulating enzyme activity associated with inflammatory responses and neurodegenerative diseases. Preliminary research suggests that this compound can interact with specific enzymatic sites, potentially inhibiting pathways that contribute to disease progression. The nitrogen-rich structure allows for hydrogen bonding and hydrophobic interactions, which are crucial for establishing stable binding with biological targets.

The synthesis of 8,11-diazatricyclo4.3.3.0,1,6dodecane involves complex organic transformations that require precise control over reaction conditions to achieve high yields and purity. Advanced synthetic methodologies, including transition metal-catalyzed cyclizations and ring-closing metathesis reactions, have been employed to construct the tricyclic core efficiently. These synthetic strategies not only enhance the accessibility of the compound but also provide opportunities for structural modifications to optimize its pharmacological properties.

One of the most compelling aspects of 8,11-diazatricyclo4.3.3.0,1,6dodecane is its potential as a lead compound for further drug development. By leveraging computational chemistry techniques such as molecular docking and quantum mechanical calculations, researchers can predict how this molecule might interact with various biological targets at an atomic level. This approach enables the identification of key binding residues and functional groups that can be modified to improve potency and reduce side effects.

Current research is also exploring the pharmacokinetic profile of 8,11-diazatricyclo4.3.3.0,1,6dodecane, aiming to understand its absorption, distribution, metabolism, and excretion (ADME) properties. These studies are crucial for assessing the compound's bioavailability and determining optimal dosing regimens for therapeutic applications. Additionally, toxicological evaluations are being conducted to ensure safety and identify any potential liabilities before moving into clinical trials.

The versatility of 8,11-diazatricyclo4.3.3.0,1,6dodecane extends beyond its initial applications in inflammation and neurodegeneration; it also shows promise in addressing other therapeutic areas such as oncology and infectious diseases. By modifying specific functional groups within the tricyclic framework or exploring derivatives with different substituents, scientists can tailor the compound's properties to target diverse disease mechanisms.

As our understanding of molecular interactions continues to evolve through interdisciplinary approaches combining chemistry、biology、and computer science,compounds like 8,11-diazatricyclo4。3。3。0,1,6dodecane are poised to play a pivotal role in next-generation drug discovery programs。The integration of innovative synthetic methodologies with cutting-edge computational tools ensures that researchers can rapidly identify promising candidates while minimizing experimental trial-and-error。

In conclusion,the compound with CAS No.25682-47-7and product name 8,11-diazatricyclo4。3。3。0,1,6dodecane represents a significant advancement in pharmaceutical research due to its unique structural featuresand potential therapeutic applications.Further studies are warrantedto fully elucidate its pharmacological profileand explore its potential asa lead compoundfor drug development.With continued innovationin synthetic chemistryand computational biology,this classoftricyclicamineis likelyto make substantial contributions toimproving human health worldwide.

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