• 1. Kinetic resolution and parallel kinetic resolution of methyl (±)-5-alkyl-cyclopentene-1-carboxylates for the asymmetric synthesis of 5-alkyl-cispentacin derivatives
  Stephen G. Davies,A. Christopher Garner,Marcus J. C. Long,Rachel M. Morrison,Paul M. Roberts,Edward D. Savory,Andrew D. Smith,Miles J. Sweet,Jonathan M. Withey Org. Biomol. Chem. 2005 3 2762
• 2. Asymmetric synthesis of (1R,2S,3R)-γ-methyl-cis-pentacin by a kinetic resolution protocol
  Simon Bailey,Stephen G. Davies,Andrew D. Smith,Jonathan M. Withey Chem. Commun. 2002 2910
• 3. Preparation of methyl (1R,2S,5S)- and (1S,2R,5R)-2-amino-5-tert-butyl-cyclopentane-1-carboxylates by parallel kinetic resolution of methyl (RS)-5-tert-butyl-cyclopentene-1-carboxylate
  Stephen G. Davies,David Díez,Mohamed M. El Hammouni,A. Christopher Garner,Narciso M. Garrido,Marcus J. C. Long,Rachel M. Morrison,Andrew D. Smith,Miles J. Sweet,Jonathan M. Withey Chem. Commun. 2003 2410
• 4. Preparation of methyl (1R,2S,5S)- and (1S,2R,5R)-2-amino-5-tert-butyl-cyclopentane-1-carboxylates by parallel kinetic resolution of methyl (RS)-5-tert-butyl-cyclopentene-1-carboxylate
  Stephen G. Davies,David Díez,Mohamed M. El Hammouni,A. Christopher Garner,Narciso M. Garrido,Marcus J. C. Long,Rachel M. Morrison,Andrew D. Smith,Miles J. Sweet,Jonathan M. Withey Chem. Commun. 2003 2410
• 5. N-Terminal peptidic boronic acids selectively inhibit human ClpXP
  Kenneth Knott,Jennifer Fishovitz,Steven B. Thorpe,Irene Lee,Webster L. Santos Org. Biomol. Chem. 2010 8 3451

• Solvents and Organic Chemicals Organic Compounds Organic acids and derivatives Carboxylic acids and derivatives Carboxylic acid esters
• Solvents and Organic Chemicals Organic Compounds Organic acids and derivatives Carboxylic acids and derivatives Carboxylic acid derivatives Carboxylic acid esters

Comprehensive Guide to Methyl Cyclopent-1-ene-1-carboxylate (CAS No. 25662-28-6): Properties, Applications, and Industry Insights

Methyl cyclopent-1-ene-1-carboxylate (CAS No. 25662-28-6) is a specialized organic compound widely recognized for its unique molecular structure and versatile applications in synthetic chemistry. This ester derivative of cyclopentene features a carboxylate group, making it a valuable intermediate in pharmaceuticals, fragrances, and advanced material synthesis. With growing interest in sustainable chemistry and bio-based materials, researchers are increasingly exploring its potential in green synthesis routes and catalytic processes.

The compound’s cyclopentene backbone contributes to its reactivity, enabling diverse transformations such as Diels-Alder reactions or hydrogenation. Its methyl ester functionality enhances solubility in organic solvents, facilitating its use in industrial-scale reactions. Recent studies highlight its role in synthesizing chiral building blocks for drug development, aligning with the pharmaceutical industry’s demand for enantioselective methodologies. Keywords like "cyclopentene derivatives" and "ester synthesis" frequently appear in academic literature, reflecting its scientific relevance.

From an industrial perspective, methyl cyclopent-1-ene-1-carboxylate is gaining traction due to its compatibility with flow chemistry and continuous manufacturing—a trend driven by efficiency and waste reduction. Environmental concerns have also spurred interest in its biodegradability profile, with researchers investigating its breakdown pathways. Common search queries such as "applications of cyclopentene carboxylates" or "CAS 25662-28-6 suppliers" indicate strong market interest, particularly from R&D teams in specialty chemicals.

Analytical characterization of this compound typically involves GC-MS, NMR, and FTIR techniques, ensuring purity for high-value applications. Regulatory compliance, such as REACH registration, further underscores its commercial viability. As industries pivot toward bio-based feedstocks, derivatives like methyl cyclopent-1-ene-1-carboxylate are positioned as sustainable alternatives to petroleum-based intermediates, addressing global searches for "green chemistry solutions."

Innovations in catalysis have expanded its utility, with recent patents describing its use in asymmetric synthesis—a response to the demand for "chiral auxiliaries" in agrochemicals and APIs. Safety data sheets emphasize standard organic lab practices, though its classification avoids hazardous thresholds, making it accessible for academic and industrial labs alike. The compound’s stability under inert atmospheres also supports its use in high-temperature reactions, a topic frequently queried in technical forums.

Looking ahead, the integration of methyl cyclopent-1-ene-1-carboxylate into AI-driven molecular design platforms exemplifies its future potential. Computational chemists leverage its structural motifs to predict novel reactivity patterns, aligning with trends in "digital chemistry tools." As synthetic biology advances, enzymatic routes to produce such esters may emerge, further enhancing its sustainability profile—a key focus for researchers searching "biocatalysis for ester formation."

In summary, CAS No. 25662-28-6 represents a dynamic intersection of traditional organic synthesis and modern technological demands. Its adaptability across sectors—from fragrances to advanced materials—ensures its continued relevance, while evolving regulatory and environmental standards drive innovation in its production and applications.

• 150240-36-1(2-Butenedioic acid, 2-methyl-3-tetradecyl-, dimethyl ester, (2Z)-)
• 25662-30-0(1-Cyclopentene-1-carboxylic acid, 2-methyl-, methyl ester)
• 13368-79-1(1-Cyclopentene-1,2-dicarboxylicacid, 1,2-dimethyl ester)
• 140614-70-6(2,6,10-Dodecatrienoic acid, 12-hydroxy-6,10-dimethyl-2-(4-methyl-3-pentenyl)-, methyl ester, (E,E,E)- (9CI))
• 141364-79-6(2,20-Docosadiene-2,3,20,21-tetracarboxylic acid, tetramethyl ester, (Z,Z)- (9CI))
• 344747-26-8(1-Cyclopentene-1-carboxylic acid, 2-(hydroxymethyl)-, methyl ester (9CI))
• 106060-31-5(Hexanedioic acid, 2,5-diethylidene-, dimethyl ester, (E,E)-)
• 104157-09-7(Hexadecanoic acid, 2-(1-methylethylidene)-, methyl ester)
• 344751-62-8(2-(methoxycarbonyl)cyclopent-1-enecarboxylic acid)
• 154617-42-2(2-Butenedioic acid, 2-pentyl-, dimethyl ester, (2Z)-)