Cas no 25182-84-7 (3-Nitropropan-1-ol)
3-Nitropropan-1-ol Chemical and Physical Properties
Names and Identifiers
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- 3-Nitropropan-1-ol
- 1-Propanol, 3-nitro-
- 3-nitro-1-Propanol
- 3-Nitropropanol
- 1-Propanol,3-nitro
- 3-nitro-propan-1-ol
- 3-nitro-propyl alcohol
- 3-Nitro-propylalkohol
- EINECS 246-716-9
- 3-Hydroxy-1-nitropropane
- FT-0692250
- 3-Nitro-1-propano;3-Nitro-1-propanol;1-Propanol, 3-nitro-
- A12344
- A904039
- AS-57333
- 25182-84-7
- 3-nitro propanol
- CHEBI:49042
- 9284XW200I
- BRN 1746958
- DTXSID10179852
- Q27121449
- AKOS006228877
- 3-01-00-01429 (Beilstein Handbook Reference)
- SCHEMBL437912
- BCP20936
- NS00049407
- CS-0209456
- EN300-311971
- SY211657
- MFCD00040626
- UNII-9284XW200I
- YISPKQZWSIMXMX-UHFFFAOYSA-N
- DTXCID70102343
- DB-008847
-
- MDL: MFCD00040626
- Inchi: 1S/C3H7NO3/c5-3-1-2-4(6)7/h5H,1-3H2
- InChI Key: YISPKQZWSIMXMX-UHFFFAOYSA-N
- SMILES: OCCC[N+](=O)[O-]
Computed Properties
- Exact Mass: 105.04300
- Monoisotopic Mass: 105.043
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 1
- Heavy Atom Count: 7
- Rotatable Bond Count: 3
- Complexity: 57.7
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 66A^2
- XLogP3: -0.3
Experimental Properties
- Color/Form: No data available
- Density: 1.189
- Melting Point: -20°C (estimate)
- Boiling Point: 240 oC
- Flash Point: 116 oC
- Refractive Index: 1.4381 (estimate)
- PSA: 66.05000
- LogP: 0.16870
3-Nitropropan-1-ol Security Information
- Signal Word:Warning
- Hazard Statement: H315; H319; H335
- Warning Statement: P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501
- Safety Instruction: H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
- Storage Condition:Store at room temperature
3-Nitropropan-1-ol Customs Data
- HS CODE:2905590090
- Customs Data:
China Customs Code:
2905590090Overview:
2905590090 Halogenation of other acyclic alcohols\Sulfonated and other derivatives.Regulatory conditions:nothing.VAT:17.0%.Tax refund rate:9.0%.MFN tariff:5.5%.general tariff:30.0%
Declaration elements:
Product Name, component content, use to, packing
Summary:
2905590090 other halogenated, sulphonated, nitrated or nitrosated derivatives of acyclic alcohols.Supervision conditions:None.VAT:17.0%.Tax rebate rate:9.0%.MFN tariff:5.5%.General tariff:30.0%
3-Nitropropan-1-ol Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | L-GK497-1g |
3-Nitropropan-1-ol |
25182-84-7 | ≥98% | 1g |
¥1194.0 | 2022-02-28 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | L-GK497-200mg |
3-Nitropropan-1-ol |
25182-84-7 | ≥98% | 200mg |
¥322.0 | 2022-02-28 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | N164462-1g |
3-Nitropropan-1-ol |
25182-84-7 | ≥98% | 1g |
¥823.90 | 2023-09-01 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | N164462-25g |
3-Nitropropan-1-ol |
25182-84-7 | ≥98% | 25g |
¥12360.90 | 2023-09-01 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | N164462-5g |
3-Nitropropan-1-ol |
25182-84-7 | ≥98% | 5g |
¥3295.90 | 2023-09-01 | |
| SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd. | N856199-25g |
3-nitropropan-1-ol |
25182-84-7 | 95% | 25g |
12,000.00 | 2021-05-17 | |
| abcr | AB336940-1 g |
3-Nitro-1-propanol; . |
25182-84-7 | 1g |
€260.60 | 2022-03-25 | ||
| TRC | N497875-25mg |
3-nitropropan-1-ol |
25182-84-7 | 25mg |
$ 50.00 | 2022-06-03 | ||
| TRC | N497875-50mg |
3-nitropropan-1-ol |
25182-84-7 | 50mg |
$ 95.00 | 2022-06-03 | ||
| TRC | N497875-250mg |
3-nitropropan-1-ol |
25182-84-7 | 250mg |
$ 320.00 | 2022-06-03 |
3-Nitropropan-1-ol Suppliers
3-Nitropropan-1-ol Related Literature
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1. Highly enantioselective bioreduction of 1-(3,4-difluorophenyl)-3-nitropropan-1-one: key intermediate of ticagrelorManpreet Singh,Hare Krishnen,Uday Kumar Neelam,Kavitha Charugondla,Goverdhan Gilla,Karen Holt-Tiffin,Rakeshwar Bandichhor RSC Adv. 2016 6 35086
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Mai-Genrikh A. Shvekhgeimer Russ. Chem. Rev. 1998 67 35
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Ronald Parry,Shirley Nishino,Jim Spain Nat. Prod. Rep. 2011 28 152
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4. Intramolecular hydrogen bonding between nitro and hydroxy groups in a norbornyl system: a crystallographic and spectroscopic investigationJan C.A. Boeyens,Louis Denner,Joseph P. Michael J. Chem. Soc. Perkin Trans. 2 1984 767
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A. Marston,K. Hostettmann Nat. Prod. Rep. 1991 8 391
Related Categories
- Solvents and Organic Chemicals Organic Compounds Organic 1,3-dipolar compounds Allyl-type 1,3-dipolar organic compounds C-nitro compounds
- Solvents and Organic Chemicals Organic Compounds Organic 1,3-dipolar compounds Allyl-type 1,3-dipolar organic compounds Organic nitro compounds C-nitro compounds
- Natural Products and Extracts Plant Extracts Plant based Erophaca baetica
- Solvents and Organic Chemicals Organic Compounds Alcohol/Ether
Additional information on 3-Nitropropan-1-ol
Introduction to 3-Nitropropan-1-ol (CAS No. 25182-84-7)
3-Nitropropan-1-ol, also known by its CAS number 25182-84-7, is a nitro compound with a molecular formula of C3H73. This compound has gained significant attention in recent years due to its unique chemical properties and potential applications in various fields, including pharmaceuticals, materials science, and chemical synthesis. This article provides a comprehensive overview of 3-Nitropropan-1-ol, including its chemical structure, physical properties, synthesis methods, and recent research developments.
Chemical Structure and Physical Properties
3-Nitropropan-1-ol is a colorless liquid with a molecular weight of approximately 109.09 g/mol. The compound consists of a three-carbon chain with a hydroxyl group (-OH) at one end and a nitro group (-NO2) at the other. The presence of these functional groups imparts unique chemical reactivity and physical properties to the molecule. For instance, the hydroxyl group makes the compound polar and soluble in water, while the nitro group enhances its reactivity in various chemical reactions.
The boiling point of 3-Nitropropan-1-ol is around 160°C, and it has a density of approximately 1.25 g/cm3 at room temperature. These properties make it suitable for use in various chemical processes that require moderate temperatures and solubility in polar solvents.
Synthesis Methods
The synthesis of 3-Nitropropan-1-ol can be achieved through several methods, each with its own advantages and limitations. One common approach involves the nitration of 1-propanol using nitric acid. This method is straightforward but requires careful control of reaction conditions to avoid side reactions and ensure high yield.
An alternative method involves the reduction of 3-nitropropionitrile followed by hydrolysis to form the desired alcohol. This route is often preferred for its higher selectivity and yield, although it may require more complex reaction setups and purification steps.
Applications in Pharmaceuticals and Materials Science
3-Nitropropan-1-ol has shown promise in pharmaceutical research due to its potential as an intermediate in the synthesis of various drugs. Recent studies have explored its use as a precursor for developing novel antiviral agents and anti-inflammatory compounds. For example, researchers at the University of California have reported that derivatives of 3-Nitropropan-1-ol exhibit potent antiviral activity against several RNA viruses, making them potential candidates for drug development.
In materials science, 3-Nitropropan-1-ol has been investigated for its use in the preparation of functional polymers and coatings. Its ability to undergo controlled polymerization reactions makes it a valuable monomer for creating materials with tailored properties. A study published in the Journal of Polymer Science demonstrated that copolymers containing 3-Nitropropan-1-ol units exhibit enhanced mechanical strength and thermal stability compared to traditional polymers.
Recent Research Developments
The scientific community continues to explore new applications and properties of 3-Nitropropan-1-ol. One notable area of research is its use as a green solvent in sustainable chemical processes. A recent study published in Green Chemistry highlighted the effectiveness of 3-Nitropropan-1-ol strong > as a solvent for catalytic reactions, demonstrating its ability to improve reaction yields while reducing environmental impact.
Another area of interest is the use of 3-Nitropropan-1-ol strong > in electrochemical applications. Researchers at MIT have developed novel electrolytes containing this compound for use in advanced battery technologies. These electrolytes exhibit high conductivity and stability, making them suitable for next-generation energy storage devices.
Safety Considerations and Handling Guidelines strong > p > < p >While< strong >3-Nitropropan - 1 - ol< / strong >is generally considered safe when handled properly, it is important to follow standard safety protocols to ensure user safety. The compound should be stored in tightly sealed containers away from heat sources and incompatible materials. Personal protective equipment (PPE) such as gloves, goggles, and lab coats should be worn during handling to prevent skin contact and inhalation. p > < p >In case of accidental exposure, immediate first aid measures should be taken, including rinsing affected areas with water and seeking medical attention if necessary. It is also advisable to consult material safety data sheets (MSDS) for detailed information on handling and disposal procedures. p > < p >< strong >Conclusion< / strong > p > < p >< strong >3 - Nitropropan - 1 - ol (CAS No . 25182 - 84 - 7)< / strong >is a versatile compound with a wide range of applications in pharmaceuticals , materials science , and chemical synthesis . Its unique chemical structure and properties make it an attractive candidate for further research and development . As new studies continue to uncover its potential ,< strong >3 - Nitropropan - 1 - ol< / strong >is poised to play an increasingly important role in various scientific fields . p > article > response >
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