Cas no 2509-26-4 (4,4'-Bis(methoxymethyl)diphenyl ether)

4,4'-Bis(methoxymethyl)diphenyl ether is a specialized organic compound featuring a central diphenyl ether core with methoxymethyl substituents at the para positions. This structure imparts unique solubility and reactivity characteristics, making it valuable as an intermediate in fine chemical synthesis, particularly in the production of polymers, resins, and crosslinking agents. The methoxymethyl groups enhance its compatibility with polar solvents and facilitate further functionalization. Its stability under moderate conditions and controlled reactivity make it suitable for applications requiring precise molecular modifications. The compound is often utilized in advanced material science and pharmaceutical research, where tailored ether-based architectures are essential.
4,4'-Bis(methoxymethyl)diphenyl ether structure
2509-26-4 structure
Product Name:4,4'-Bis(methoxymethyl)diphenyl ether
CAS No:2509-26-4
MF:C16H18O3
MW:258.312325000763
MDL:MFCD00082840
CID:43083
PubChem ID:75635
Update Time:2025-05-27

4,4'-Bis(methoxymethyl)diphenyl ether Chemical and Physical Properties

Names and Identifiers

    • 4,4'-Oxybis((methoxymethyl)benzene)
    • Bis(alpha-methoxy-p-tolyl) ether
    • 1-(methoxymethyl)-4-[4-(methoxymethyl)phenoxy]benzene
    • 4,4'-BIS(METHOXYMETHYL)DIPHENYL ETHER
    • 1,1'-oxybis[4-(methoxymethyl)benzene]
    • 4,4'-Bis-methoxymethyl diphenyl ether
    • Bis-<4-methoxymethyl-phenyl>-aether
    • EINECS 219-722-4
    • Benzene, 1,1'-oxybis[4-(methoxymethyl)-
    • bis(4-methoxymethylphenyl) ether
    • BMWBYLGWPWDACF-UHFFFAOYSA-N
    • bis-(4-methoxymethylphenyl) ether
    • bis-(alpha-methoxy-p-tolyl) ether
    • 4,4-Bismethoxymethyldiphenyl Ether
    • Benzene, 1,1'-oxybis(4-(methoxymethyl)-
    • Ether, bis(.alpha.-methoxy-p-tolyl)
    • DTXSID90179779
    • D91884
    • NS00027807
    • SCHEMBL6327626
    • MFCD00082840
    • AKOS016000699
    • 1,1'-OXYBIS(4-(METHOXYMETHYL)BENZENE)
    • 4,4'-Oxybis[(methoxymethyl)benzene]
    • KCF4ZXZ9P8
    • O0537
    • A817638
    • bis-(I+/--methoxy-p-tolyl) ether
    • 4,4'-bis(methoxymethyl)diphenylether
    • AS-64063
    • Benzene,1,1'-oxybis[(methoxymethyl)-
    • UNII-KCF4ZXZ9P8
    • 1,1 inverted exclamation marka-Oxybis[4-(methoxymethyl)benzene]
    • FT-0634334
    • 2509-26-4
    • CS-0210633
    • DB-046618
    • DTXCID00102270
    • ETHER, BIS(ALPHA-METHOXY-P-TOLYL)
    • 219-722-4
    • 4,4'-Bis(methoxymethyl)diphenyl ether
    • MDL： MFCD00082840
    • Inchi： 1S/C16H18O3/c1-17-11-13-3-7-15(8-4-13)19-16-9-5-14(6-10-16)12-18-2/h3-10H,11-12H2,1-2H3
    • InChI Key： BMWBYLGWPWDACF-UHFFFAOYSA-N
    • SMILES： O(C1C=CC(COC)=CC=1)C1C=CC(COC)=CC=1

Computed Properties

  • Exact Mass: 258.12600
  • Monoisotopic Mass: 258.126
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 19
  • Rotatable Bond Count: 6
  • Complexity: 204
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 27.7
  • XLogP3: 2.8

Experimental Properties

  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 161°C/2mmHg(lit.)
  • Flash Point: 113.0±23.8 °C
  • Refractive Index: 1.544
  • PSA: 27.69000
  • LogP: 3.77170
  • Vapor Pressure: 0.0±0.7 mmHg at 25°C

4,4'-Bis(methoxymethyl)diphenyl ether Security Information

4,4'-Bis(methoxymethyl)diphenyl ether Customs Data

  • HS CODE：2909309090
  • Customs Data：

    China Customs Code:

    2909309090

    Overview:

    2909309090 Other aromatic ethers and their halogenated derivatives\sulfonation\Nitrated derivative(Including nitrosative derivatives).Regulatory conditions:nothing.VAT:17.0%.Tax refund rate:9.0%.MFN tariff:5.5%.general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    2909309090 other aromatic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

4,4'-Bis(methoxymethyl)diphenyl ether Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
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 2509-26-4
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 2509-26-4 97.0%(GC)
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Ambeed
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eNovation Chemicals LLC
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eNovation Chemicals LLC
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4,4'-Bis(methoxymethyl)diphenyl ether Related Literature

Related Categories

Additional information on 4,4'-Bis(methoxymethyl)diphenyl ether

Recent Advances in the Study of 4,4'-Bis(methoxymethyl)diphenyl ether (CAS: 2509-26-4) in Chemical and Biomedical Applications

4,4'-Bis(methoxymethyl)diphenyl ether (CAS: 2509-26-4) is a chemical compound that has garnered significant attention in recent years due to its potential applications in the fields of polymer chemistry, pharmaceuticals, and material science. This compound, characterized by its ether linkage and methoxymethyl substituents, exhibits unique physicochemical properties that make it a valuable intermediate in synthetic chemistry. Recent studies have explored its utility in drug delivery systems, polymer crosslinking, and as a precursor for advanced materials. This research brief aims to summarize the latest findings and highlight the emerging trends in the application of 4,4'-Bis(methoxymethyl)diphenyl ether.

One of the most notable advancements in the study of 4,4'-Bis(methoxymethyl)diphenyl ether is its role in the development of novel drug delivery systems. Researchers have demonstrated that this compound can be functionalized to create biocompatible carriers for targeted drug release. For instance, a 2023 study published in the Journal of Controlled Release reported the synthesis of a polymer-drug conjugate using 4,4'-Bis(methoxymethyl)diphenyl ether as a linker, which exhibited enhanced stability and controlled release kinetics in vitro. The study highlighted the compound's potential to improve the therapeutic efficacy of hydrophobic drugs by facilitating their solubilization and sustained release.

In addition to its pharmaceutical applications, 4,4'-Bis(methoxymethyl)diphenyl ether has been investigated for its utility in polymer chemistry. A recent study in Macromolecules (2024) explored its use as a crosslinking agent in the synthesis of high-performance thermosetting resins. The researchers found that the incorporation of this compound into epoxy resins resulted in materials with improved thermal stability and mechanical properties, making them suitable for aerospace and automotive applications. The study also noted the compound's low toxicity and environmental compatibility, which are critical factors for industrial adoption.

Furthermore, the chemical versatility of 4,4'-Bis(methoxymethyl)diphenyl ether has been leveraged in the development of advanced materials. A 2024 publication in Advanced Materials described its use as a precursor for the synthesis of porous organic polymers (POPs) with high surface areas and tunable pore sizes. These POPs exhibited exceptional performance in gas storage and separation, highlighting the compound's potential in addressing challenges related to energy storage and environmental remediation. The study underscored the importance of structural modifications to optimize the material properties for specific applications.

Despite these promising developments, challenges remain in the large-scale production and commercialization of 4,4'-Bis(methoxymethyl)diphenyl ether-based products. Issues such as cost-effectiveness, scalability, and regulatory compliance need to be addressed to fully realize its potential. Ongoing research is focused on optimizing synthetic routes and exploring new applications in biomedicine and materials science. Collaborative efforts between academia and industry are expected to drive innovation and overcome these barriers in the coming years.

In conclusion, 4,4'-Bis(methoxymethyl)diphenyl ether (CAS: 2509-26-4) represents a versatile and promising compound with wide-ranging applications in chemical and biomedical fields. Recent studies have demonstrated its potential in drug delivery, polymer chemistry, and advanced materials, paving the way for future innovations. As research continues to uncover new functionalities and applications, this compound is poised to play a pivotal role in addressing some of the most pressing challenges in science and technology.

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