Cas no 2503-29-9 (Benzyl (1-amino-1-oxopropan-2-yl)carbamate)

Benzyl (1-amino-1-oxopropan-2-yl)carbamate structure
2503-29-9 structure
Product Name:Benzyl (1-amino-1-oxopropan-2-yl)carbamate
CAS No:2503-29-9
MF:C11H14N2O3
MW:222.240462779999
MDL:MFCD00136699
CID:851426
PubChem ID:4092845
Update Time:2025-11-01

Benzyl (1-amino-1-oxopropan-2-yl)carbamate Chemical and Physical Properties

Names and Identifiers

    • Benzyl (1-amino-1-oxopropan-2-yl)carbamate
    • 2-(CBZ-AMINO)PROPANAMIDE
    • Benzyl (1-amino-1-oxo-2-propanyl)carbamate
    • Carbamic acid, (2-amino-1-methyl-2-oxoethyl)-, phenylmethyl ester, (±)-
    • (+-)-2-Benzyloxycarbonylamino-propionsaeure-amid
    • (2-amino-1-methyl-2-oxoethyl)carbamic acid phenylmethyl ester
    • (Z)-Diethyl-1-phenyl-2-bromvinylphosphat
    • Benzyloxycarbonyl-DL-alanin-amid
    • Cbz-alanine-NH2
    • CTK1B9761
    • N-benzyloxycarbonylalanine amide
    • N-Benzyloxycarbonyl-DL-alaninamid
    • Phosphoric acid, (1Z)-2-bromo-1-phenylethenyl diethyl ester
    • Z-Diaethyl-1-phenyl-2-bromvinyl-phosphat
    • Z-DL-Ala-NH2
    • N-Cbz-DL-alanine amide
    • (R)-2-(Cbz-amino)propanamide
    • DTXSID901212497
    • benzyl N-(1-amino-1-oxopropan-2-yl)carbamate
    • CARBOBENZYLOXY-DL-ALANINAMIDE
    • SY021103
    • MFCD00136699
    • DB-351066
    • CHEMBL5306217
    • CS-0450118
    • BS-22128
    • SY104596
    • BENZYL N-(1-CARBAMOYLETHYL)CARBAMATE
    • AC5728
    • Z-Ala-NH
    • CAA50329
    • Benzyl(1-amino-1-oxopropan-2-yl)carbamate
    • Carbamic acid, N-(2-amino-1-methyl-2-oxoethyl)-, phenylmethyl ester
    • Phenylmethyl N-(2-amino-1-methyl-2-oxoethyl)carbamate
    • 2503-29-9
    • SCHEMBL591894
    • Z-D-Ala-NH
    • MFCD00237324
    • AKOS022183676
    • MDL: MFCD00136699
    • Inchi: 1S/C11H14N2O3/c1-8(10(12)14)13-11(15)16-7-9-5-3-2-4-6-9/h2-6,8H,7H2,1H3,(H2,12,14)(H,13,15)
    • InChI Key: CTZZSWNVVFTJRN-UHFFFAOYSA-N
    • SMILES: O(C(NC(C(N)=O)C)=O)CC1C=CC=CC=1

Computed Properties

  • Exact Mass: 222.10044231g/mol
  • Monoisotopic Mass: 222.10044231g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 5
  • Heavy Atom Count: 16
  • Rotatable Bond Count: 6
  • Complexity: 250
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 1
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 0.8
  • Topological Polar Surface Area: 81.4?2

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Additional information on Benzyl (1-amino-1-oxopropan-2-yl)carbamate

Comprehensive Overview of Benzyl (1-amino-1-oxopropan-2-yl)carbamate (CAS No. 2503-29-9)

Benzyl (1-amino-1-oxopropan-2-yl)carbamate, identified by its CAS No. 2503-29-9, is a specialized organic compound with significant applications in pharmaceutical and biochemical research. This compound, often referred to as a protected amino acid derivative, plays a crucial role in peptide synthesis and drug development. Its unique structure, featuring a benzyl carbamate group and an amide functionality, makes it a versatile intermediate for constructing complex molecules. Researchers and industries value this compound for its stability and reactivity under controlled conditions.

In recent years, the demand for custom peptide synthesis and small molecule pharmaceuticals has surged, driven by advancements in personalized medicine and biotechnology. Benzyl (1-amino-1-oxopropan-2-yl)carbamate aligns with these trends, as it is frequently employed in the synthesis of peptide-based therapeutics and enzyme inhibitors. Its role in facilitating selective amide bond formation has made it a staple in laboratories focusing on proteomics and drug discovery. This compound’s relevance is further highlighted by its mention in patents and scientific literature related to cancer research and neurological disorders.

From a chemical perspective, CAS No. 2503-29-9 exhibits properties that cater to high-yield reactions and minimal side products. Its solubility in organic solvents like dimethylformamide (DMF) and dichloromethane (DCM) ensures compatibility with standard synthetic protocols. The compound’s carbamate protection strategy is particularly advantageous in solid-phase peptide synthesis (SPPS), where orthogonal deprotection is required. These attributes have positioned it as a preferred choice for medicinal chemists and bioconjugation experts.

The growing interest in sustainable chemistry and green synthesis has also influenced the use of Benzyl (1-amino-1-oxopropan-2-yl)carbamate. Researchers are exploring eco-friendly alternatives for traditional reagents, and this compound’s efficiency aligns with such initiatives. Additionally, its application in biodegradable materials and bioactive coatings has garnered attention in materials science. These interdisciplinary applications underscore its adaptability beyond traditional pharmaceutical uses.

For those seeking detailed spectral data or synthetic protocols involving CAS No. 2503-29-9, reputable chemical databases and peer-reviewed journals are invaluable resources. The compound’s NMR spectra, mass spectrometry profiles, and chromatographic behavior are well-documented, aiding in quality control and method development. Furthermore, its compatibility with automated synthesis platforms makes it a practical choice for high-throughput screening.

In conclusion, Benzyl (1-amino-1-oxopropan-2-yl)carbamate (CAS No. 2503-29-9) is a multifaceted compound with broad utility in modern science. Its integration into cutting-edge research and alignment with industry trends ensure its continued relevance. Whether for academic investigations or industrial-scale production, this compound remains a cornerstone in the toolkit of chemists and biologists alike.

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