Cas no 24947-73-7 (Cysteine,N-acetyl-S-methyl-)

N-Acetyl-S-methyl-L-cysteine is a modified cysteine derivative characterized by the acetylation of the amino group and methylation of the thiol group. This structural modification enhances its stability compared to free cysteine, reducing susceptibility to oxidation and degradation. The compound is utilized in biochemical research as a thiol-blocking agent or precursor in peptide synthesis, where controlled reactivity of the sulfur moiety is required. Its acetyl group improves membrane permeability, making it useful in cellular studies. The methylated thiol group offers selective reactivity, enabling applications in protein modification and protection strategies. This derivative is particularly valuable in studies requiring controlled thiol chemistry under physiological conditions.
Cysteine,N-acetyl-S-methyl- structure
Cysteine,N-acetyl-S-methyl- structure
Product Name:Cysteine,N-acetyl-S-methyl-
CAS No:24947-73-7
MF:C6H11NO3S
MW:177.221440553665
CID:266896
PubChem ID:306124
Update Time:2025-05-28

Cysteine,N-acetyl-S-methyl- Chemical and Physical Properties

Names and Identifiers

    • Cysteine,N-acetyl-S-methyl-
    • 2-acetamido-3-methylsulfanylpropanoic acid
    • 2-acetylamino-3-(methylthio)propanoic acid
    • AC1L787X
    • AGN-PC-00OCSF
    • DL-2-Acetamino-3-methylmercapto-propionsaeure
    • DL-Cysteine, N-acetyl-S-methyl-
    • DL-N-acetyl-S-methylcysteine
    • N-Acetyl-S-methyl-cystein
    • N-acetyl-S-methylcysteine
    • N-acetyl-S-methyl-cysteine
    • NSC203775
    • 2-acetamido-3-(methylsulfanyl)propanoic acid
    • FT-0661298
    • NSC-203775
    • DTXSID80308410
    • EN300-7005341
    • SCHEMBL4952983
    • AB31228
    • AKOS010293175
    • N-Fmyl-D-Methionine
    • 24947-73-7
    • Inchi: 1S/C6H11NO3S/c1-4(8)7-5(3-11-2)6(9)10/h5H,3H2,1-2H3,(H,7,8)(H,9,10)
    • InChI Key: RYGLCORNOFFGTB-UHFFFAOYSA-N
    • SMILES: S(C)CC(C(=O)O)NC(C)=O

Computed Properties

  • Exact Mass: 177.04603
  • Monoisotopic Mass: 177.046
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 4
  • Complexity: 160
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 1
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: -0.2
  • Topological Polar Surface Area: 91.7?2

Experimental Properties

  • Density: 1.243
  • Boiling Point: 430.3°Cat760mmHg
  • Flash Point: 214.1°C
  • Refractive Index: 1.515
  • PSA: 66.4
  • LogP: 0.32960

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