Cas no 2494-12-4 (N-acetyldopamine)

N-Acetyldopamine is a biologically active derivative of dopamine, characterized by the acetylation of the amine group. This modification enhances its stability and alters its reactivity, making it valuable in biochemical and pharmacological research. The compound serves as a key intermediate in the synthesis of melanin and sclerotization agents in insects, contributing to cuticle hardening. Its structural properties also facilitate studies on neurotransmitter pathways and oxidative processes. N-Acetyldopamine is utilized in crosslinking reactions due to its catechol moiety, offering insights into polymer and material science applications. High purity grades ensure reproducibility in experimental settings, supporting rigorous scientific investigations.

N-acetyldopamine structure

Product Name:N-acetyldopamine

CAS No:2494-12-4

MF:C₁₀H₁₃NO₃

MW:195.215122938156

MDL:MFCD00037174

CID:272214

PubChem ID:100526

Update Time:2025-06-08

N-acetyldopamine Chemical and Physical Properties

Names and Identifiers

- Acetamide,N-[2-(3,4-dihydroxyphenyl)ethyl]-
- Acetamide,N-(2-(3,4-dihydroxyphenyl)ethyl)
- Acetamide,N-(3,4-dihydroxyphenethyl)
- Acetamide,N-(3,4-dihydroxyphenethyl)-(7CI,8CI)
- N-(3,4-dihydroxy-phenethyl)-acetamide
- N-[2-(3,4-dihydroxybenzene)ethyl]acetamide
- N-[2-(3,4-Dihydroxyphenyl)ethyl]acetamid
- N-acetyl dopamine
- N-Acetyldopamine monohydrate
- N-acetyldopamine
- NCGC00093595-01
- CHEMBL137743
- MFCD00037174
- NS00014829
- AYU97G37EM
- NCGC00093595-02
- EU-0100093
- Acetamide, N-(2-(3,4-dihydroxyphenyl)ethyl)-
- N-[2-(3,4-dihydroxyphenyl)ethyl]ethanimidic acid
- BRD-K95847244-001-01-9
- NCGC00015101-03
- BRN 2806306
- NCGC00015101-01
- HY-N7493
- Acetamide,4-dihydroxyphenyl)ethyl]-
- NSC 314644
- Q27216289
- n-[2-(3,4-dihydroxyphenyl)ethyl]acetamide
- SR-01000075692-1
- N-(3,4-Dihydroxyphenethyl)acetamide
- CCG-204188
- A 8762
- N-(2-(3,4-Dihydroxyphenyl)ethyl)acetamide (ACD/Name 4.0)
- AKOS003589558
- N-acetyl-dopamine
- Acetamide, N-(3,4-dihydroxyphenethyl)-
- SR-01000075692
- NSC-314644
- BDBM50035608
- N-(3,4-Dihydroxyphenethyl)-Acetamide
- D70944
- EN300-1692211
- NSC314644
- SCHEMBL328568
- Z68159731
- Lopac-A-8762
- Acetamide, N-[2-(3,4-dihydroxyphenyl)ethyl]-
- CHEBI:125678
- 7DP
- CAA49412
- AS-56736
- 2494-12-4
- Acetamide,4-dihydroxyphenethyl)-
- CS-0130036
- DTXSID70179656
- Lopac0_000093
- {N-[2-(3,} 4-dihydroxyphenyl)ethyl]-Acetamide
- NCGC00015101-02
- NADA
- N-(2-(3,4-dihydroxyphenyl)ethyl)ethanimidic acid
- DA-55967
- DTXCID30102147
- (N-(2-(3,) 4-dihydroxyphenyl)ethyl)-acetamide
- N-(2-(3,4-dihydroxyphenyl)ethyl)acetamide
- Acetamide, N-(3,4-dihydroxyphenethyl)-(7CI,8CI)
- MDL： MFCD00037174
- Inchi： 1S/C10H13NO3/c1-7(12)11-5-4-8-2-3-9(13)10(14)6-8/h2-3,6,13-14H,4-5H2,1H3,(H,11,12)
- InChI Key： OFSAJYZMIPNPHE-UHFFFAOYSA-N
- SMILES： OC1=C(C=CC(=C1)CCNC(C)=O)O

Computed Properties

Exact Mass: 195.09000
Monoisotopic Mass: 195.09
Isotope Atom Count: 0
Hydrogen Bond Donor Count: 3
Hydrogen Bond Acceptor Count: 3
Heavy Atom Count: 14
Rotatable Bond Count: 3
Complexity: 196
Covalently-Bonded Unit Count: 1
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count : 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Topological Polar Surface Area: 69.6?2
XLogP3: _0.7

Experimental Properties

Density: 1.235
Boiling Point: 486.7°Cat760mmHg
Flash Point: 248.1°C
Refractive Index: 1.578
PSA: 69.56000
LogP: 1.16730

N-acetyldopamine Security Information

RTECS：AB7651000
Storage Condition：?20°C

N-acetyldopamine Customs Data

HS CODE：2924299090
Customs Data：

China Customs Code:
2924299090

Overview:

2924299090. Other cyclic amides(Including cyclic carbamates)(Including their derivatives as well as their salts). VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:30.0%

Declaration elements:

Product Name, component content, use to, packing

Summary:

2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

N-acetyldopamine Pricemore >>

Related Categories	No.	Product Name	Cas No.	Purity	Specification	Price	update time
ChemScence	CS-0130036-100mg	N-acetyldopamine	2494-12-4	98.85%	100mg	$100.0	2022-04-27
ChemScence	CS-0130036-250mg	N-acetyldopamine	2494-12-4	98.85%	250mg	$150.0	2022-04-27
SHANG HAI XIAN DING Biotechnology Co., Ltd.	B-ZB151-200mg	N-acetyldopamine	2494-12-4	97%	200mg	651.0CNY	2021-07-17
SHANG HAI XIAN DING Biotechnology Co., Ltd.	B-ZB151-50mg	N-acetyldopamine	2494-12-4	97%	50mg	260.0CNY	2021-07-17
MedChemExpress	HY-N7493-100mg	N-acetyldopamine	2494-12-4	99.23%	100mg	￥1000	2024-07-20
MedChemExpress	HY-N7493-250mg	N-acetyldopamine	2494-12-4	99.23%	250mg	￥1500	2024-07-20
SHANG HAI XIAN DING Biotechnology Co., Ltd.	B-ZB151-1g	N-acetyldopamine	2494-12-4	97%	1g	1954.0CNY	2021-07-17
SHANG HAI XIAN DING Biotechnology Co., Ltd.	B-ZB151-250mg	N-acetyldopamine	2494-12-4	97%	250mg	2469CNY	2021-05-07
SHANG HAI XIAN DING Biotechnology Co., Ltd.	B-ZB151-100mg	N-acetyldopamine	2494-12-4	97%	100mg	1084CNY	2021-05-07
SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd.	X19565-100mg	N-(3,4-Dihydroxyphenethyl)acetamide	2494-12-4	97%	100mg	￥481.0	2024-07-18

N-acetyldopamine Suppliers

Amadis Chemical Company Limited

Gold Member

Audited Supplier

(CAS:2494-12-4)N-acetyldopamine

Order Number:A1008892

Stock Status:in Stock

Quantity:1g/5g

Purity:99%

Pricing Information Last Updated:Thursday, 29 August 2024 15:08

Price ($):253.0/744.0

Email:[email protected]

Product Official Link

N-acetyldopamine Related Literature

1. Distinct correlation between (CN2)x units and pores: a low-cost method for predesigned wide range control of micropore size of porous carbon?

Xiaotong Feng,Lei Bian,Jie Ma,Lei Zhou,Xiayan Wang,Guangsheng Guo,Qiaosheng Pu Chem. Commun., 2019,55, 3963-3966
2. Evidence of CO2 molecule acting as an electron acceptor on a nanoporous metal–organic-framework MIL-53 or Cr3+(OH)(O2C–C6H4–CO2)?

Alexandre Vimont,Arnaud Travert,Philippe Bazin,Jean-Claude Lavalley,Marco Daturi,Christian Serre,Gérard Férey,Sandrine Bourrelly,Philip L. Llewellyn Chem. Commun., 2007, 3291-3293
3. Excellent electrochemical performance of LiFe0.4Mn0.6PO4 microspheres produced using a double carbon coating process?

Yong Ping Huang,Tao Tao,Zheng Chen,Wei Han,Ying Wu,Chunjiang Kuang,Shaoxiong Zhou,Ying Chen J. Mater. Chem. A, 2014,2, 18831-18837
4. Evidence of field induced slow magnetic relaxation in cis-[Co(hfac)2(H2O)2] exhibiting tri-axial anisotropy with a negative axial component?

Denis V. Korchagin,Elena A. Yureva,Alexander V. Akimov,Eugenii Ya. Misochko,Gennady V. Shilov,Artem D. Talantsev,Roman B. Morgunov,Alexander A. Shakin,Sergey M. Aldoshin,Boris S. Tsukerblat Dalton Trans., 2017,46, 7540-7548
5. Evolutionary de novo design of phenothiazine derivatives for dye-sensitized solar cells?

Vishwesh Venkatraman,Marco Foscato,Vidar R. Jensen,Bj?rn K?re Alsberg J. Mater. Chem. A, 2015,3, 9851-9860

Related Categories

Additional information on N-acetyldopamine

Comprehensive Guide to N-Acetyldopamine (CAS No. 2494-12-4): Properties, Applications, and Research Insights

N-Acetyldopamine (CAS No. 2494-12-4), a biologically active derivative of dopamine, has garnered significant attention in biochemical and pharmaceutical research. This compound, also known as NAD, plays a pivotal role in insect cuticle sclerotization and has potential applications in human health due to its structural similarity to neurotransmitters. With growing interest in natural compounds and neuroprotective agents, N-acetyldopamine is increasingly studied for its antioxidant properties and possible therapeutic benefits.

The molecular structure of N-acetyldopamine combines the catechol moiety of dopamine with an acetyl group, enhancing its stability and bioavailability. Researchers are exploring its role in oxidative stress mitigation, a hot topic in aging and neurodegenerative disease research. Recent studies suggest that N-acetyldopamine derivatives may influence cell signaling pathways, making them candidates for drug development targeting conditions like Parkinson's disease.

In the context of sustainable biomaterials, N-acetyldopamine has emerged as a key component in insect-derived polymers. Its ability to cross-link proteins has inspired bioengineers to develop eco-friendly adhesives and coatings, aligning with the global push for green chemistry solutions. This application addresses frequent search queries about biodegradable alternatives to synthetic materials.

Analytical techniques for N-acetyldopamine quantification have advanced significantly, with HPLC-MS becoming the gold standard. Scientists frequently search for optimal extraction methods and chromatographic conditions when working with this compound, reflecting its growing importance in analytical biochemistry. The compound's UV absorption characteristics at 280 nm make it particularly suitable for spectroscopic analysis.

From a commercial perspective, N-acetyldopamine suppliers are seeing increased demand from both academic and industrial sectors. The compound's purity specifications (typically >98% for research use) and storage conditions (recommended at -20°C) are common search terms among procurement specialists. Quality control protocols emphasize the importance of HPLC validation and mass spectrometry confirmation for research-grade material.

Emerging research explores N-acetyldopamine's potential in cosmeceuticals, capitalizing on its antioxidant properties. This aligns with consumer interest in anti-aging ingredients and natural skincare actives. Preliminary studies suggest it may inhibit tyrosinase activity, making it relevant to discussions about hyperpigmentation treatments - a trending topic in dermatological searches.

The biosynthesis pathway of N-acetyldopamine in insects involves N-acetyltransferase enzymes, a subject of interest for biocatalysis researchers. This connects to popular searches about enzyme engineering and metabolic pathway optimization. Comparative studies between insect and mammalian dopamine metabolism are shedding light on evolutionary adaptations in neurotransmitter regulation.

In pharmacokinetic studies, researchers are investigating N-acetyldopamine's blood-brain barrier permeability, a critical factor for potential CNS applications. This addresses frequent queries about bioavailability enhancement strategies for neuroactive compounds. The acetyl modification appears to improve metabolic stability compared to dopamine itself.

Quality publications about N-acetyldopamine research have increased by 40% in the past five years, according to major scientific databases. Common search combinations include "N-acetyldopamine synthesis," "biological activities of N-acetyldopamine," and "CAS 2494-12-4 suppliers." The compound's Safety Data Sheet information is also frequently requested, emphasizing the need for proper handling protocols.

Future directions for N-acetyldopamine studies may focus on its receptor interactions and potential as a multi-target therapeutic agent. With increasing interest in neuroinflammation and mitochondrial dysfunction in disease pathology, this dopamine derivative offers intriguing possibilities for translational research bridging entomology and human medicine.

2494-12-4 (N-acetyldopamine) Related Products

Recommended suppliers