Cas no 24764-66-7 (1-(4-Methoxy-1-naphthalenyl)-ethanone)

1-(4-Methoxy-1-naphthalenyl)-ethanone is a naphthalene derivative featuring a methoxy substituent at the 4-position and an acetyl group at the 1-position of the naphthalene ring. This compound is of interest in organic synthesis due to its structural versatility, serving as a key intermediate in the preparation of pharmaceuticals, agrochemicals, and specialty chemicals. The methoxy group enhances electron density, influencing reactivity in electrophilic substitution and cross-coupling reactions. Its crystalline form and well-defined melting point ensure consistent purity, making it suitable for precise synthetic applications. The compound’s stability under standard conditions further supports its utility in multi-step synthetic routes.
1-(4-Methoxy-1-naphthalenyl)-ethanone structure
24764-66-7 structure
Product Name:1-(4-Methoxy-1-naphthalenyl)-ethanone
CAS No:24764-66-7
MF:C13H12O2
MW:200.233183860779
MDL:MFCD00156696
CID:52568
PubChem ID:249921
Update Time:2025-10-31

1-(4-Methoxy-1-naphthalenyl)-ethanone Chemical and Physical Properties

Names and Identifiers

    • 1-(4-Methoxynaphthalen-1-yl)ethanone
    • 1-(4-methoxy-1-naphthalenyl)Ethanone
    • 1-(4-METHOXY-1-NAPHTHYL)ETHANONE
    • 1-acetyl-4-methoxynaphthalene
    • 4'-methoxy-1'-acetonaphthone
    • 1-(4-methoxy-1-naphthalenyl)-Ethanone
    • Ethanone, 1-(4-methoxy-1-naphthalenyl)-
    • 1-(4-methoxynaphthalen-1-yl)ethan-1-one
    • NSC68821
    • PubChem13589
    • KSC493C0F
    • RSBOFKOICCVYNF-UHFFFAOYSA-
    • 1909AB
    • SBB067071
    • M
    • SR-01000061007-1
    • MFCD00156696
    • SCHEMBL4518755
    • AM20040009
    • NSC-68821
    • FT-0652629
    • DTXSID40290463
    • EN300-11548
    • SY046247
    • 1-(4-methoxynaphthalen-1-yl)ethanone;1-Acetyl-4-methoxynaphthalene
    • Q-101450
    • SR-01000061007
    • 24764-66-7
    • 1-(4-methoxy-1-naphthyl)ethanone, AldrichCPR
    • 1-(4-methoxy-naphthalen-1-yl)-ethanone
    • CS-0042895
    • InChI=1/C13H12O2/c1-9(14)10-7-8-13(15-2)12-6-4-3-5-11(10)12/h3-8H,1-2H3
    • AC1231
    • DS-4959
    • Methoxy-1-naphthyl)ethanone
    • Z57050140
    • A5073
    • AKOS000346110
    • DB-067266
    • ALBB-025530
    • 1-(4-Methoxy-1-naphthalenyl)-ethanone
    • MDL： MFCD00156696
    • Inchi： 1S/C13H12O2/c1-9(14)10-7-8-13(15-2)12-6-4-3-5-11(10)12/h3-8H,1-2H3
    • InChI Key： RSBOFKOICCVYNF-UHFFFAOYSA-N
    • SMILES： O(C)C1C=CC(C(C)=O)=C2C=CC=CC2=1

Computed Properties

  • Exact Mass: 200.08400
  • Monoisotopic Mass: 200.083729621 g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 15
  • Rotatable Bond Count: 2
  • Complexity: 237
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 26.3
  • Molecular Weight: 200.23
  • XLogP3: 2.8

Experimental Properties

  • Density: 1.118
  • Boiling Point: 366.2℃ at 760mmHg
  • Flash Point: 366.2°Cat760mmHg
  • Refractive Index: 1.594
  • PSA: 26.30000
  • LogP: 3.05100

1-(4-Methoxy-1-naphthalenyl)-ethanone Customs Data

  • HS CODE：2914509090
  • Customs Data：

    China Customs Code:

    2914509090

    Overview:

    2914509090 Ketones containing other oxygen-containing groups. VAT:17.0% Tax refund rate:9.0% Regulatory conditions:nothing MFN tariff:5.5% general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to, Acetone declared packaging

    Summary:

    HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

1-(4-Methoxy-1-naphthalenyl)-ethanone Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd.
M859779-5g
1-(4-Methoxy-1-Naphthyl)Ethanone
 24764-66-7 ≥98%
5g
 167.40 2021-05-17
TRC
M331373-100mg
1-(4-Methoxy-1-naphthalenyl)-ethanone
 24764-66-7
100mg
 $115.00 2023-05-17
TRC
M331373-250mg
1-(4-Methoxy-1-naphthalenyl)-ethanone
 24764-66-7
250mg
 $224.00 2023-05-17
TRC
M331373-500mg
1-(4-Methoxy-1-naphthalenyl)-ethanone
 24764-66-7
500mg
 $345.00 2023-05-17
TRC
M331373-1g
1-(4-Methoxy-1-naphthalenyl)-ethanone
 24764-66-7
1g
 $494.00 2023-05-17
SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd.
M54830-250mg
1-(4-Methoxynaphthalen-1-yl)ethanone
 24764-66-7 97%
250mg
 ￥19.0 2024-07-19
SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd.
M54830-5g
1-(4-Methoxynaphthalen-1-yl)ethanone
 24764-66-7 97%
5g
 ￥30.0 2024-07-19
SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd.
M54830-10g
1-(4-Methoxynaphthalen-1-yl)ethanone
 24764-66-7 97%
10g
 ￥40.0 2024-07-19
SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd.
M54830-1g
1-(4-Methoxynaphthalen-1-yl)ethanone
 24764-66-7 97%
1g
 ￥24.0 2024-07-19
SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd.
M54830-25g
1-(4-Methoxynaphthalen-1-yl)ethanone
 24764-66-7 97%
25g
 ￥149.0 2022-04-27

1-(4-Methoxy-1-naphthalenyl)-ethanone Suppliers

Amadis Chemical Company Limited
Gold Member
Audited Supplier Audited Supplier
(CAS:24764-66-7)1-(4-Methoxy-1-naphthalenyl)-ethanone
Order Number:A5073
Stock Status:in Stock
Quantity:500g
Purity:99%
Pricing Information Last Updated:Monday, 2 September 2024 16:03
Price ($):373.0
Tiancheng Chemical (Jiangsu) Co., Ltd
Gold Member
Audited Supplier Audited Supplier
(CAS:24764-66-7)4-Methoxy-1-Naphthyl Ethyl Ketone
Order Number:LE119
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 11:37
Price ($):discuss personally

1-(4-Methoxy-1-naphthalenyl)-ethanone Related Literature

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Additional information on 1-(4-Methoxy-1-naphthalenyl)-ethanone

Recent Advances in the Study of 1-(4-Methoxy-1-naphthalenyl)-ethanone (CAS: 24764-66-7) in Chemical Biology and Pharmaceutical Research

1-(4-Methoxy-1-naphthalenyl)-ethanone (CAS: 24764-66-7) is a naphthalene derivative that has garnered significant attention in recent years due to its potential applications in chemical biology and pharmaceutical research. This compound, characterized by its methoxy-substituted naphthalene core, has been investigated for its unique chemical properties and biological activities. Recent studies have explored its role as a synthetic intermediate, its pharmacological potential, and its mechanisms of action at the molecular level.

In a 2023 study published in the Journal of Medicinal Chemistry, researchers demonstrated that 1-(4-Methoxy-1-naphthalenyl)-ethanone exhibits promising inhibitory effects on specific kinase enzymes involved in inflammatory pathways. The study utilized molecular docking simulations and in vitro assays to elucidate the binding affinity of the compound to target proteins. These findings suggest potential therapeutic applications for inflammatory diseases, although further in vivo studies are required to validate these effects.

Another notable advancement was reported in a 2024 paper in Bioorganic & Medicinal Chemistry Letters, where the compound was used as a key intermediate in the synthesis of novel anticancer agents. The research team modified the ethanone moiety to enhance its reactivity, enabling the creation of a library of derivatives with improved cytotoxic activity against cancer cell lines. This highlights the versatility of 1-(4-Methoxy-1-naphthalenyl)-ethanone in drug discovery and its potential as a scaffold for developing targeted therapies.

From a chemical biology perspective, recent work has focused on understanding the photophysical properties of 1-(4-Methoxy-1-naphthalenyl)-ethanone. A 2023 study in Chemical Communications revealed that the compound exhibits unique fluorescence characteristics under specific conditions, making it a candidate for use as a molecular probe in cellular imaging. This property could be leveraged to study intracellular processes or to track drug delivery mechanisms in real-time.

Despite these promising developments, challenges remain in the practical application of 1-(4-Methoxy-1-naphthalenyl)-ethanone. Issues such as solubility, stability, and selectivity need to be addressed to fully realize its potential in pharmaceutical formulations. Ongoing research is exploring nanoformulation techniques and prodrug strategies to overcome these limitations.

In conclusion, 1-(4-Methoxy-1-naphthalenyl)-ethanone (CAS: 24764-66-7) represents a compound of growing importance in chemical biology and pharmaceutical research. Its diverse applications—from kinase inhibition to anticancer agent synthesis and molecular imaging—demonstrate its versatility. As research continues to uncover new properties and applications for this molecule, it is likely to play an increasingly significant role in the development of novel therapeutic agents and research tools.

24764-66-7 (1-(4-Methoxy-1-naphthalenyl)-ethanone) Related Products

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Amadis Chemical Company Limited
(CAS:24764-66-7)1-(4-Methoxy-1-naphthalenyl)-ethanone
A5073
Purity:99%
Quantity:500g
Price ($):373.0
Email
Tiancheng Chemical (Jiangsu) Co., Ltd
(CAS:24764-66-7)4-Methoxy-1-Naphthyl Ethyl Ketone
LE119
Purity:99%
Quantity:25KG,200KG,1000KG
Price ($):Inquiry
Email