Dexrazoxane Chemical and Physical Properties

Names and Identifiers

- (S)-4,4'-(Propane-1,2-diyl)bis(piperazine-2,6-dione)
- Dexrazoxane
- (S)-4,4'-(Propane-1,2-diyl)-bis(piperazine-2,6-dione)
- (S)-1,2-Bis(3,5-dioxo-1-piperazinyl)propane
- 4-[(2S)-2-(3,5-dioxopiperazin-1-yl)propyl]piperazine-2,6-dione
- ICRF187
- NSC169780
- (S)-4,4'-(1-Methyl-1,2-ethanediyl)bis-2,6-piperazinedione
- Zinecard
- Cardioxane
- Dexrazoxano
- Dexrazoxanum
- Dextrorazoxane
- Dexrazoxanum [INN-Latin]
- Dexrazoxano [INN-Spanish]
- Desrazoxane
- Eucardion
- ADR 529
- ICRF 187
- (+)-(S)-4,4'-Propylenedi-2,6-piperazinedione
- Dexrazone
- (+)-1,2-Bis(3,5-dioxo-1-piperazinyl)propane
- dyzoxane
- Ra
- ICRF-187
- ADR-529
- NSC-169780
- CAS-24584-09-6
- DS-1394
- MFCD00866449
- BIDD:GT0068
- NCGC00263544-01
- (+)-1,5-dioxopiperazin-1-yl)propane
- SCHEMBL18400
- Dexrazoxanum (INN-Latin)
- NS00073041
- 2,6-Piperazinedione, 4, 4'-(1-methyl-1,2-ethanediyl)bis-, (S)-
- 2,6-Piperazinedione, 4,4'-(1-methyl-1,2-ethanediyl)bis-, (S)-
- (S)-4,4'-(propane-1,2-diyl)dipiperazine-2,6-dione
- NSC 169780
- V03AF02
- NCI60_001367
- (2S)-4,4'-(Propane-1,2-diyl)bis(piperazine-2,6-dione)
- Dexrazoxane (JAN/USAN/INN)
- AB01273932_03
- 6-hydroxy-4-[(2S)-2-(5-hydroxy-3-oxo-1,2,3,6-tetrahydropyrazin-1-yl)propyl]-2,3,4,5-tetrahydropyrazin-2-one
- 4-[(2S)-1-(3,5-dioxopiperazin-1-yl)propan-2-yl]piperazine-2,6-dione
- DEXRAZOXANE [HSDB]
- AB01273932-01
- MLS006010158
- Razoxane (+)-form
- A817380
- UNII-048L81261F
- 4,4'-(2S)-propane-1,2-diyldipiperazine-2,6-dione
- s5651
- 048L81261F
- 2,6-Piperazinedione, 4,4'-propylenedi-, (+)-
- DEXRAZOXANE [VANDF]
- RAZOXANE (+)-FORM [MI]
- 2, 4,4'-propylenedi-, (+)-
- Tox21_112256_1
- (+)-(S)-4,4'-(1-Methyl-1,2-ethanediyl)di(2,6-piperazinedione)
- Razoxanum [INN-Latin]
- 2,4,4'-(1-methyl-1,2-ethanediyl)bis-, (S)-
- CHEBI:50223
- SR-01000883995-5
- BD164365
- SR-01000883995
- J-015579
- NCGC00263544-02
- AKOS015896392
- Tox21_112256
- NCGC00164737-01
- CCRIS 9394
- CHEMBL1738
- HY-B0581
- DB00380
- D03730
- BRD-K07265709-003-01-5
- DEXRAZOXANE [USAN]
- DTXCID1020647
- SR-01000883995-2
- DEXRAZOXANE [WHO-DD]
- Dexrazoxano (INN-Spanish)
- DEXRAZOXANE [MART.]
- 24584-09-6
- (S)-(+)-1,5-dioxopiperazin-1-yl)propane
- Razoxane, (S)-Isomer
- SMR002529680
- DEXRAZOXANE (MART.)
- (+)-dexrazoxane
- Dexrazoxane, analytical reference material
- BRN 5759131
- Q524995
- AB01273932-02
- DTXSID3040647
- 2,6-Piperazinedione, 4,4'-[(1S)-1-methyl-1,2-ethanediyl]bis-
- Dexrazoxane, >=95% (HPLC)
- 2,6-Piperazinedione, 4,4'-(1-methyl-1,2-ethanediyl)bis-, (+)-
- Soluble ICRF (L-isomer)
- Dexrazoxane [USAN:INN:BAN]
- (+)-1,2-Bis(3,5-dioxopiperazin-1-yl)propane
- CCG-267131
- AMY39004
- 4-((2S)-2-(3,5-dioxopiperazin-1-yl)propyl)piperazine-2,6-dione
- EN300-7356981
- GTPL7330
- Razoxana [INN-Spanish]
- D4227
- (S)-(+)-1,2-Bis(3,5-dioxopiperazin-1-yl)propane
- J-520219
- BDBM50586360
- 2,6-Piperazinedione, 4,4'-(1-methyl-1,2-ethanediyl)bis-,(S)-
- 4,4'-[(1S)-1-Methyl-1,2-ethanediyl]bis-2,6-piperazinedione
- Razoxane, d-
- DEXRAZOXANE [JAN]
- HSDB 7319
- DEXRAZOXANE [INN]
- DEXRAZOXANE [EMA EPAR]
- 2, 6-Piperazinedione, 4,4'-propylenedi-, (P)-
- Dexrazoxane- Bio-X
- 4,4'-[(2S)-1,2-Propanediyl]di(2,6-piperazinedione)
- 2,4,4'-[(1S)-1-methyl-1,2-ethanediyl]bis-
- Razoxane, (s)-
- Soluble ICRF (L-isosomer)
- Dexrazoxan
- SR-01000883995-1
- 2,6-Piperazinedione, 4,4'propylenedi-,(P)-
- BRD-K07265709-003-04-9
- Dexrazoxane?
- BRD-K07265709-003-05-6
- BRD-K07265709-003-03-1
- MDL： MFCD00866449
- Inchi： 1S/C11H16N4O4/c1-7(15-5-10(18)13-11(19)6-15)2-14-3-8(16)12-9(17)4-14/h7H,2-6H2,1H3,(H,12,16,17)(H,13,18,19)/t7-/m0/s1
- InChI Key： BMKDZUISNHGIBY-ZETCQYMHSA-N
- SMILES： O=C1CN(CC(N1)=O)[C@@H](C)CN1CC(NC(C1)=O)=O
- BRN： 5759131

Computed Properties

Exact Mass: 268.11700
Monoisotopic Mass: 268.117155
Isotope Atom Count: 0
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 6
Heavy Atom Count: 19
Rotatable Bond Count: 3
Complexity: 404
Covalently-Bonded Unit Count: 1
Defined Atom Stereocenter Count: 1
Undefined Atom Stereocenter Count : 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Surface Charge: 0
Tautomer Count: 25
XLogP3: -1.4
Topological Polar Surface Area: 98.8

Experimental Properties

Color/Form: No data available
Density: 1.333
Melting Point: 193.0 to 197.0 deg-C
Boiling Point: 531.5°C at 760 mmHg
Flash Point: 275.3±30.1 °C
Refractive Index: 1.539
Solubility: DMSO: >20mg/mL
PSA: 98.82000
LogP: -2.17490
Merck: 8123
pka: 2.1(at 25℃)
Specific Rotation: +11.0 ~ +12.0° (c=5, DMF)

Dexrazoxane Security Information

Symbol:
Prompt：warning
Signal Word：Warning
Hazard Statement： H315-H319-H335
Warning Statement： P261-P305 + P351 + P338
Hazardous Material transportation number：UN 2811 6.1 / PGIII
WGK Germany：3
Hazard Category Code： 36/37/38
Safety Instruction： 26-36
RTECS：TL6390000
Hazardous Material Identification：
HazardClass：6.1
PackingGroup：III
Storage Condition：Please store the product under the recommended conditions in the Certificate of Analysis.

Dexrazoxane Customs Data

HS CODE：2933599090
Customs Data：

China Customs Code:
2933599090

Overview:

2933599090. Other compounds with pyrimidine ring in structure(Including other compounds with piperazine ring on the structure. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

Declaration elements:

Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

Summary:

2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Dexrazoxane Pricemore >>

Related Categories	No.	Product Name	Cas No.	Purity	Specification	Price	update time
SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd.	D134376-100mg	Dexrazoxane	24584-09-6	97%	100mg	￥136.90	2023-09-03
SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd.	D134376-250mg	Dexrazoxane	24584-09-6	97%	250mg	￥235.90	2023-09-03
SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd.	D134376-25mg	Dexrazoxane	24584-09-6	97%	25mg	￥72.90	2023-09-03
SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd.	D134376-50mg	Dexrazoxane	24584-09-6	97%	50mg	￥85.90	2023-09-03
SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd.	D134376-5mg	Dexrazoxane	24584-09-6	97%	5mg	￥41.90	2023-09-03
S e l l e c k ZHONG GUO	S5651-25mg	Dexrazoxane	24584-09-6	99.95%	25mg	￥794.46	2023-09-15
S e l l e c k ZHONG GUO	S5651-100mg	Dexrazoxane	24584-09-6	99.95%	100mg	￥1392.44	2023-09-15
SHANG HAI YI EN HUA XUE JI SHU Co., Ltd.	R030586-5mg	Dexrazoxane	24584-09-6	98%	5mg	￥610	2024-05-24
SHANG HAI YI EN HUA XUE JI SHU Co., Ltd.	R030586-50mg	Dexrazoxane	24584-09-6	98%	50mg	￥84	2024-05-24
SHANG HAI YI EN HUA XUE JI SHU Co., Ltd.	R030586-250mg	Dexrazoxane	24584-09-6	98%	250mg	￥230	2024-05-24

Dexrazoxane Production Method

Dexrazoxane Suppliers

Tiancheng Chemical (Jiangsu) Co., Ltd

Gold Member

Audited Supplier

(CAS:24584-09-6)右雷佐生

Order Number:LE25856862;LE765

Stock Status:in Stock

Quantity:25KG,200KG,1000KG

Purity:99%

Pricing Information Last Updated:Friday, 20 June 2025 12:50

Price ($):discuss personally

Email:[email protected]

Dexrazoxane Related Literature

1. Synthesis and analysis of novel analogues of dexrazoxane and its open-ring hydrolysis product for protection against anthracycline cardiotoxicity in vitro and in vivo

Anna Jirkovská-Vávrová,Jaroslav Roh,Olga Len?ová-Popelová,Eduard Jirkovsky,Kate?ina Hru?ková,Eli?ka Pot??ková-Macková,Hana Jansová,Pavlína Ha?ková,Pavla Martinková,Tomá? Eisner,Marek Kratochvíl,Jan ??s,Miloslav Machá?ek,Lucie Vostatková-Tichotová,Vladimír Ger?l,Danuta S. Kalinowski,Mark T. Muller,Des R. Richardson,Kate?ina Vávrová,Martin ?těrba,Tomá? ?im?nek Toxicol. Res. 2015 4 1098
2. A dual-fluorescent whole-well imaging approach for screening active compounds against doxorubicin-induced cardiotoxicity from natural products

Yaqi Chen,Lijuan Sun,Yi Wang,Xiaoping Zhao RSC Adv. 2015 5 106431
3. Biodegradable porous polymeric drug as a drug delivery system: alleviation of doxorubicin-induced cardiotoxicity via passive targeted release

Qiuhong Jiao,Baoting Liu,Xiufeng Xu,Tao Huang,Bufan Cao,Lide Wang,Qingguo Wang,Ailing Du,Jingtian Li,Baolong Zhou,Tao Wang RSC Adv. 2023 13 5444
4. The role of iron in doxorubicin-induced cardiotoxicity: recent advances and implication for drug delivery

Yan Qin,Tao Guo,Zheng Wang,Yanjun Zhao J. Mater. Chem. B 2021 9 4793
5. Iron(iii)-binding of the anticancer agents doxorubicin and vosaroxin

Katja Dralle Mjos,Jacqueline F. Cawthray,Gene Jamieson,Judith A. Fox,Chris Orvig Dalton Trans. 2015 44 2348

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Cas no 24584-09-6 (Dexrazoxane)

Dexrazoxane Chemical and Physical Properties

Names and Identifiers

Computed Properties

Experimental Properties

Dexrazoxane Security Information

Dexrazoxane Customs Data

China Customs Code:

Overview:

Declaration elements:

Summary:

Dexrazoxane Pricemore >>

Dexrazoxane Production Method

Dexrazoxane Suppliers

Dexrazoxane Related Literature

24584-09-6 (Dexrazoxane) Related Products