Cas no 2446-62-0 (6H,7H,8H,9H,11H-pyrido2,1-bquinazolin-11-one)
6H,7H,8H,9H,11H-pyrido2,1-bquinazolin-11-one Chemical and Physical Properties
Names and Identifiers
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- 8,9-Dihydro-6H-pyrido[2,1-b]quinazolin-11(7H)-one
- 6,7,8,9-tetrahydropyrido[2,1-b]quinazolin-11-one
- 8,9-Dihydro-6H-pyrido[2,1-b]quizolin-11(7H)-one
- CS-0214984
- 2,3-tetramethylene-3,4-dihydroquinazol-4-one
- EN300-211116
- 6,7,8,9-tetrahydro-11H-pyrido[2,1-b]quinazolin-11-one
- DTXSID30335231
- STK099926
- LMDWOGWJYVSXEP-UHFFFAOYSA-N
- 11H-Pyrido[2,1-b]quinazolin-11-one, 6,7,8,9-tetrahydro
- Z1509566963
- 2,3-Butanoquinazoline-4(3H)-one
- 6, 7, 8, 9-tetrahydropyrido[2, 1-b]quinazolin-11-one
- CHEMBL1191898
- SCHEMBL5511965
- AKOS005396712
- 6H,7H,8H,9H,11H-pyrido[2,1-b]quinazolin-11-one
- CAA44662
- 2446-62-0
- DB-342051
- 6H,7H,8H,9H,11H-pyrido2,1-bquinazolin-11-one
-
- MDL: MFCD00661747
- Inchi: 1S/C12H12N2O/c15-12-9-5-1-2-6-10(9)13-11-7-3-4-8-14(11)12/h1-2,5-6H,3-4,7-8H2
- InChI Key: LMDWOGWJYVSXEP-UHFFFAOYSA-N
- SMILES: O=C1C2C=CC=CC=2N=C2CCCCN21
Computed Properties
- Exact Mass: 200.09506
- Monoisotopic Mass: 200.094963011g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 3
- Heavy Atom Count: 15
- Rotatable Bond Count: 0
- Complexity: 311
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 1.3
- Topological Polar Surface Area: 32.7?2
Experimental Properties
- PSA: 32.67
6H,7H,8H,9H,11H-pyrido2,1-bquinazolin-11-one Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Alichem | A029185792-1g |
8,9-Dihydro-6H-pyrido[2,1-b]quinazolin-11(7H)-one |
2446-62-0 | 95% | 1g |
$582.08 | 2023-09-02 | |
| TRC | H326225-5mg |
6H,7H,8H,9H,11H-pyrido[2,1-b]quinazolin-11-one |
2446-62-0 | 5mg |
$ 50.00 | 2022-06-04 | ||
| TRC | H326225-10mg |
6H,7H,8H,9H,11H-pyrido[2,1-b]quinazolin-11-one |
2446-62-0 | 10mg |
$ 70.00 | 2022-06-04 | ||
| TRC | H326225-50mg |
6H,7H,8H,9H,11H-pyrido[2,1-b]quinazolin-11-one |
2446-62-0 | 50mg |
$ 295.00 | 2022-06-04 | ||
| Ambeed | A521497-1g |
8,9-Dihydro-6H-pyrido[2,1-b]quinazolin-11(7H)-one |
2446-62-0 | 95+% | 1g |
$2450.0 | 2024-07-28 | |
| A2B Chem LLC | AF44070-50mg |
2,3-Butanoquinazoline-4(3H)-one |
2446-62-0 | 95% | 50mg |
$277.00 | 2024-04-20 | |
| A2B Chem LLC | AF44070-100mg |
2,3-Butanoquinazoline-4(3H)-one |
2446-62-0 | 95% | 100mg |
$395.00 | 2024-04-20 | |
| A2B Chem LLC | AF44070-250mg |
2,3-Butanoquinazoline-4(3H)-one |
2446-62-0 | 95% | 250mg |
$548.00 | 2024-04-20 | |
| A2B Chem LLC | AF44070-500mg |
2,3-Butanoquinazoline-4(3H)-one |
2446-62-0 | 95% | 500mg |
$844.00 | 2024-04-20 | |
| A2B Chem LLC | AF44070-1g |
2,3-Butanoquinazoline-4(3H)-one |
2446-62-0 | 95% | 1g |
$1073.00 | 2024-04-20 |
6H,7H,8H,9H,11H-pyrido2,1-bquinazolin-11-one Suppliers
6H,7H,8H,9H,11H-pyrido2,1-bquinazolin-11-one Related Literature
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Hongxia Li,Aikifa Raza,Qiaoyu Ge,Jin-You Lu,TieJun Zhang Soft Matter, 2020,16, 6841-6849
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Bin Han,Yasuo Shimizu,Gabriele Seguini,Celia Castro,Gérard Ben Assayag,Koji Inoue,Yasuyoshi Nagai,Sylvie Schamm-Chardon,Michele Perego RSC Adv., 2016,6, 3617-3622
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Eléonore Resongles,Corinne Casiot,Fran?oise Elbaz-Poulichet,Rémi Freydier,Odile Bruneel,Christine Piot,Sophie Delpoux,Aurélie Volant,Angélique Desoeuvre Environ. Sci.: Processes Impacts, 2013,15, 1536-1544
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Weili Dai,Guangjun Wu,Michael Hunger Chem. Commun., 2015,51, 13779-13782
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Qiao Song,Angela Bamesberger,Lingyun Yang,Haley Houtwed,Haishi Cao Analyst, 2014,139, 3588-3592
Additional information on 6H,7H,8H,9H,11H-pyrido2,1-bquinazolin-11-one
Exploring the Unique Properties and Applications of 6H,7H,8H,9H,11H-pyrido[2,1-b]quinazolin-11-one (CAS No. 2446-62-0)
In the realm of heterocyclic compounds, 6H,7H,8H,9H,11H-pyrido[2,1-b]quinazolin-11-one (CAS No. 2446-62-0) stands out as a fascinating molecule with a unique structure and promising applications. This compound, often referred to by its systematic name or simply as pyrido-quinazolinone, belongs to the class of nitrogen-containing heterocycles that have garnered significant attention in pharmaceutical and materials science research.
The molecular structure of 6H,7H,8H,9H,11H-pyrido[2,1-b]quinazolin-11-one features a fused pyridine-quinazoline ring system, which contributes to its distinctive chemical properties. Researchers have been particularly interested in this compound due to its potential as a building block for more complex molecular architectures. The presence of multiple nitrogen atoms in its structure makes it an attractive candidate for hydrogen bonding interactions, a feature that is highly valued in drug design and supramolecular chemistry.
Recent studies have explored the biological activities of pyrido-quinazolinone derivatives, with particular focus on their potential as kinase inhibitors. The compound's rigid, planar structure allows for effective interaction with biological targets, making it a valuable scaffold in medicinal chemistry. While CAS 2446-62-0 itself may not be biologically active, its derivatives have shown promise in preliminary studies targeting various disease pathways.
In the field of materials science, 6H,7H,8H,9H,11H-pyrido[2,1-b]quinazolin-11-one has attracted attention for its potential applications in organic electronics. The extended π-conjugation system in its molecular structure suggests possible utility in organic light-emitting diodes (OLEDs) or as a component in organic semiconductors. Researchers are investigating how modifications to the core structure might tune its electronic properties for specific device applications.
The synthesis of pyrido[2,1-b]quinazolin-11-one typically involves multi-step organic reactions starting from readily available precursors. Recent advances in green chemistry have led to more efficient synthetic routes with improved yields and reduced environmental impact. These developments are particularly important as the scientific community seeks sustainable methods for producing valuable heterocyclic compounds.
Analytical characterization of CAS 2446-62-0 employs standard techniques including nuclear magnetic resonance (NMR) spectroscopy, mass spectrometry, and X-ray crystallography. These methods confirm the compound's structure and purity, which are crucial for its applications in research and development. The crystalline nature of this compound has facilitated detailed structural analysis, providing valuable insights into its molecular geometry and packing arrangements.
From a commercial perspective, 6H,7H,8H,9H,11H-pyrido[2,1-b]quinazolin-11-one is available from specialty chemical suppliers, typically in research quantities. The growing interest in nitrogen-rich heterocycles has led to increased demand for such compounds, particularly from pharmaceutical and academic research institutions. Suppliers often provide detailed technical data sheets and certificates of analysis to ensure researchers can properly evaluate the material for their specific needs.
Safety considerations for handling pyrido-quinazolinone derivatives follow standard laboratory protocols for organic compounds. While not classified as highly hazardous, proper personal protective equipment and good laboratory practices are recommended when working with this material. Researchers should consult the material safety data sheet (MSDS) for specific handling and storage recommendations.
The future research directions for 6H,7H,8H,9H,11H-pyrido[2,1-b]quinazolin-11-one are likely to focus on expanding its applications in drug discovery and materials science. With the increasing importance of heterocyclic compounds in these fields, this molecule serves as an important building block for developing new therapeutic agents and functional materials. Its structural features offer numerous opportunities for chemical modification, allowing researchers to tailor its properties for specific applications.
In conclusion, CAS No. 2446-62-0 represents an interesting and versatile heterocyclic compound with significant potential across multiple scientific disciplines. As research continues to uncover new applications for pyrido[2,1-b]quinazolin-11-one and its derivatives, this compound is likely to remain an important subject of investigation in both academic and industrial settings. Its unique structural features and the growing understanding of its chemical behavior make it a valuable addition to the toolkit of researchers working in medicinal chemistry, materials science, and related fields.
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