Cas no 244246-71-7 (3-bromo-2-(trifluoromethyl)aniline)

3-Bromo-2-(trifluoromethyl)aniline is a halogenated aniline derivative featuring both bromine and trifluoromethyl functional groups. This compound is valuable in organic synthesis, particularly as a versatile intermediate for pharmaceuticals, agrochemicals, and specialty materials. The presence of the electron-withdrawing trifluoromethyl group enhances reactivity in electrophilic substitution and cross-coupling reactions, while the bromine substituent facilitates further functionalization via metal-catalyzed transformations. Its structural properties make it useful for constructing complex aromatic frameworks with precise regioselectivity. The compound is typically handled under inert conditions due to its sensitivity to air and moisture. High purity grades are available to meet rigorous research and industrial application requirements.
3-bromo-2-(trifluoromethyl)aniline structure
244246-71-7 structure
Product Name:3-bromo-2-(trifluoromethyl)aniline
CAS No:244246-71-7
MF:C7H5BrF3N
MW:240.020511388779
MDL:MFCD13194482
CID:2619072
PubChem ID:12158132
Update Time:2025-05-26

3-bromo-2-(trifluoromethyl)aniline Chemical and Physical Properties

Names and Identifiers

    • 3-Bromo-2-(trifluoromethyl)aniline
    • 3-Bromo-2-(trifluoromethyl}aniline
    • DAXMSIHFYZSWNH-UHFFFAOYSA-N
    • DB-378738
    • 3-Bromo-2-(trifluoromethyl)benzenamine
    • CL9358
    • 244246-71-7
    • SY259222
    • EN300-177993
    • MFCD13194482
    • Benzenamine, 3-bromo-2-(trifluoromethyl)-
    • 3-Bromo-2-trifluoromethylaniline
    • CS-0157220
    • AS-46308
    • AKOS027252688
    • SCHEMBL22660160
    • UJA24671
    • 811-533-0
    • 3-bromo-2-(trifluoromethyl)aniline
    • MDL: MFCD13194482
    • Inchi: 1S/C7H5BrF3N/c8-4-2-1-3-5(12)6(4)7(9,10)11/h1-3H,12H2
    • InChI Key: DAXMSIHFYZSWNH-UHFFFAOYSA-N
    • SMILES: BrC1=CC=CC(=C1C(F)(F)F)N

Computed Properties

  • Exact Mass: 238.95575g/mol
  • Monoisotopic Mass: 238.95575g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 1
  • Heavy Atom Count: 12
  • Rotatable Bond Count: 1
  • Complexity: 159
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 2.8
  • Topological Polar Surface Area: 26?2

3-bromo-2-(trifluoromethyl)aniline Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
TRC
B699213-100mg
3-Bromo-2-(trifluoromethyl)aniline
244246-71-7
100mg
$ 87.00 2023-04-18
TRC
B699213-250mg
3-Bromo-2-(trifluoromethyl)aniline
244246-71-7
250mg
$ 167.00 2023-04-18
TRC
B699213-500mg
3-Bromo-2-(trifluoromethyl)aniline
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500mg
$ 265.00 2023-04-18
TRC
B699213-1g
3-Bromo-2-(trifluoromethyl)aniline
244246-71-7
1g
$ 362.00 2023-04-18
Apollo Scientific
PC53158-1g
3-Bromo-2-(trifluoromethyl)aniline
244246-71-7 95%
1g
£289.00 2025-02-21
abcr
AB358799-1 g
3-Bromo-2-(trifluoromethyl)aniline; .
244246-71-7
1g
€329.10 2023-04-26
abcr
AB358799-5 g
3-Bromo-2-(trifluoromethyl)aniline; .
244246-71-7
5g
€880.60 2023-04-26
SHANG HAI XIAN DING Biotechnology Co., Ltd.
B-ZQ618-50mg
3-bromo-2-(trifluoromethyl)aniline
244246-71-7 95+%
50mg
195.0CNY 2021-07-10
SHANG HAI XIAN DING Biotechnology Co., Ltd.
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3-bromo-2-(trifluoromethyl)aniline
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1477.0CNY 2021-07-10
SHANG HAI XIAN DING Biotechnology Co., Ltd.
B-ZQ618-200mg
3-bromo-2-(trifluoromethyl)aniline
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483.0CNY 2021-07-10

Additional information on 3-bromo-2-(trifluoromethyl)aniline

Recent Advances in the Application of 244246-71-7 and 3-bromo-2-(trifluoromethyl)aniline in Chemical Biology and Pharmaceutical Research

The chemical compound with CAS number 244246-71-7 and the derivative 3-bromo-2-(trifluoromethyl)aniline have garnered significant attention in recent pharmaceutical and chemical biology research. These compounds serve as crucial intermediates in the synthesis of novel therapeutic agents and have demonstrated potential in various biomedical applications. This research briefing synthesizes the latest findings on their synthesis, mechanisms, and applications, providing a comprehensive overview for professionals in the field.

Recent studies have highlighted the role of 244246-71-7 as a versatile scaffold in drug discovery. Its unique chemical properties enable the development of targeted inhibitors for enzymes involved in inflammatory pathways. Meanwhile, 3-bromo-2-(trifluoromethyl)aniline has been extensively studied for its utility in constructing complex molecules, particularly in the synthesis of agrochemicals and pharmaceuticals. Advanced spectroscopic techniques and computational modeling have been employed to elucidate its reactivity and stability under various conditions.

One of the groundbreaking applications of these compounds is in the development of kinase inhibitors. Researchers have successfully incorporated 3-bromo-2-(trifluoromethyl)aniline into the core structure of several kinase inhibitors, enhancing their selectivity and potency. In vitro and in vivo studies have shown promising results, with reduced off-target effects compared to traditional inhibitors. These findings underscore the potential of these compounds in next-generation therapeutics.

Moreover, the environmental impact and safety profiles of these compounds have been a focal point of recent investigations. Studies utilizing high-performance liquid chromatography (HPLC) and mass spectrometry have confirmed their biodegradability and low toxicity, making them suitable candidates for large-scale pharmaceutical production. Regulatory assessments are currently underway to evaluate their compliance with international safety standards.

In conclusion, the ongoing research on 244246-71-7 and 3-bromo-2-(trifluoromethyl)aniline highlights their pivotal role in advancing chemical biology and pharmaceutical sciences. Their applications span from drug development to agrochemical innovation, supported by robust scientific evidence. Future studies are expected to explore their potential in emerging therapeutic areas, further solidifying their importance in the field.

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